| Entry |
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| Name |
cis-abienol synthase;
Z-abienol synthase;
CAS;
ABS
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
(13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate-lyase (cis-abienol forming)
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| Reaction(IUBMB) |
(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate = cis-abienol + diphosphate [RN: R10276]
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| Reaction(KEGG) |
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| Substrate |
(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate [CPD: C20270]
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| Product |
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| Comment |
Isolated from the plants Abies balsamea (balsam fir) [1] and Nicotiana tabacum (tobacco) [2].
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| History |
EC 4.2.3.140 created 2012
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| Pathway |
| Diterpenoid biosynthesis | | Biosynthesis of secondary metabolites |
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| Orthology |
| cis-abienol synthase | | copal-8-ol diphosphate hydratase / cis-abienol synthase |
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| Reference |
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| Authors |
Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J |
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| Title |
Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production. |
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| Journal |
J. Biol. Chem. 287 (2012) 12121-31. |
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| Sequence |
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| Reference |
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| Authors |
Sallaud C, Giacalone C, Topfer R, Goepfert S, Bakaher N, Rosti S, Tissier A |
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| Title |
Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes. |
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| Journal |
Plant. J. 72 (2012) 1-17. |
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| Sequence |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |
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