| Entry |
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| Name |
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| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
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| Sysname |
3,5-dibromo-4-hydroxybenzonitrile aminohydrolase
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| Reaction(IUBMB) |
3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH3 [RN: R04349]
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| Reaction(KEGG) |
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| Substrate |
3,5-dibromo-4-hydroxybenzonitrile [CPD: C04178];
H2O [CPD: C00001]
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| Product |
3,5-dibromo-4-hydroxybenzoate [CPD: C03925];
NH3 [CPD: C00014]
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| Comment |
Involved in the bacterial degradation of the herbicide bromoxynil. Highly specific.
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| History |
EC 3.5.5.6 created 1992
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| Pathway |
| Fluorobenzoate degradation | | Microbial metabolism in diverse environments |
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| Orthology |
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| Genes |
 |
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| Reference |
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| Authors |
Stalker DM, Malyj LD, McBride KE. |
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| Title |
Purification and properties of a nitrilase specific for the herbicide bromoxynil and corresponding nucleotide sequence analysis of the bxn gene. |
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| Journal |
J. Biol. Chem. 263 (1988) 6310-4. |
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| Sequence |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: UM-BBD (Biocatalysis/Biodegradation Database): BRENDA, the Enzyme Database: CAS: 157857-12-0 |
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