KEGG   ORTHOLOGY: K21058Help
Entry
K21058                      KO                                     

Name
bciC
Definition
chlorophyllide a hydrolase [EC:3.1.1.100]
Pathway
Porphyrin and chlorophyll metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    K21058  bciC; chlorophyllide a hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.100  chlorophyllide a hydrolase
     K21058  bciC; chlorophyllide a hydrolase
BRITE hierarchy
Other DBs
RN: 
Genes
CAU: 
CAG: 
CHL: 
CTM: 
CTE: 
CPC: 
CLZ: 
CCH: 
CPH: 
CPB: 
CLI: 
Clim_1212
PVI: 
Cvib_0856
PLT: 
Plut_1085
PPH: 
Ppha_1315
PAA: 
Paes_1150
PROC: 
Ptc2401_01155
CTS: 
Ctha_2200
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Liu Z, Bryant DA
  Title
Identification of a gene essential for the first committed step in the biosynthesis of bacteriochlorophyll c.
  Journal
J Biol Chem 286:22393-402 (2011)
DOI:10.1074/jbc.M111.249433
  Sequence
[cte:CT1077] [ctm:Cabther_B0081]
KEGG   ENZYME: 3.1.1.100Help
Entry
EC 3.1.1.100                Enzyme                                 

Name
chlorophyllide a hydrolase;
bciC (gene name)
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
chlorophyllide-a hydrolase
Reaction(IUBMB)
chlorophyllide a + H2O = 8-ethyl-12-methyl-3-vinyl-bacteriochlorophyllide d + methanol + CO2 [RN:R09061]
Reaction(KEGG)
Substrate
chlorophyllide a [CPD:C02139];
H2O [CPD:C00001]
Product
8-ethyl-12-methyl-3-vinyl-bacteriochlorophyllide d;
methanol [CPD:C00132];
CO2 [CPD:C00011]
Comment
This enzyme, found in green sulfur bacteria (Chlorobiaceae) and green filamentous bacteria (Chloroflexaceae), catalyses the first committed step in the biosynthesis of bacteriochlorophylls c, d, and e, the removal of the C-132-methylcarboxyl group from chlorophyllide a. The reaction is very similar to the conversion of pheophorbide a to pyropheophorbide a during chlorophyll a degradation, which is catalysed by EC 3.1.1.82, pheophorbidase.
History
EC 3.1.1.100 created 2016
Pathway
Porphyrin and chlorophyll metabolism
Biosynthesis of secondary metabolites
Orthology
K21058  
chlorophyllide a hydrolase
Genes
CAU: 
CAG: 
CHL: 
CTM: 
CTE: 
CPC: 
CLZ: 
CCH: 
CPH: 
CPB: 
CLI: 
Clim_1212
PVI: 
Cvib_0856
PLT: 
Plut_1085
PPH: 
Ppha_1315
PAA: 
Paes_1150
PROC: 
Ptc2401_01155
CTS: 
Ctha_2200
 » show all
Taxonomy
Reference
1  [PMID:21550979]
  Authors
Liu Z, Bryant DA
  Title
Identification of a gene essential for the first committed step in the biosynthesis of bacteriochlorophyll c.
  Journal
J. Biol. Chem. 286 (2011) 22393-402.
  Sequence
[cte:CT1077] [ctm:Cabther_B0081]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
KEGG   REACTION: R09061Help
Entry
R09061                      Reaction                               

Name
chlorophyllide-a hydrolase
Definition
Chlorophyllide + H2O <=> 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + Methanol + CO2
Equation
Reaction class
C02139_C18157
Enzyme
Pathway
Porphyrin and chlorophyll metabolism
Biosynthesis of secondary metabolites
Orthology
K21058  
chlorophyllide a hydrolase [EC:3.1.1.100]
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