KEGG   MODULE: M00307Help
Entry
M00307            Pathway   Module                                 
Name
Pyruvate oxidation, pyruvate => acetyl-CoA
Definition
(((K00163,K00161+K00162)+K00627+K00382),K00169+K00170+K00171+K00172)
Module map
M00307

Orthology
pyruvate dehydrogenase complex [EC:1.2.4.1 2.3.1.12 1.8.1.4] [RN:R00209]
pyruvate:ferredoxin oxidoreductase [EC:1.2.7.1] [RN:R01196]
Ortholog tableTaxonomy
Class
Pathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
BRITE hierarchy
Pathway
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pyruvate metabolism
Reaction
Compound
C00022  
Pyruvate
C00024  
Acetyl-CoA
Comment
The oxidative decarboxylation of pyruvate to acetyl-CoA is catalyzed by the pyruvate dehydrogenase complex as part of aerobic respiration or by pyruvate:ferredoxin oxidoreductase [EC:1.2.7.1].
Other DBs
BSID: 
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