KEGG REACTION: R00575

REACTION: R00575

Entry

R00575 Reaction

Name

hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)

Definition

2 ATP + L-Glutamine + HCO3- + H2O <=> 2 ADP + Orthophosphate + L-Glutamate + Carbamoyl phosphate

Equation

2 C00002 + C00064 + C00288 + C00001 <=> 2 C00008 + C00009 + C00025 + C00169

Comment

two-step reaction (see R00575+R00256)

RPair

RP00003	C00002_C00008 ligase
RP00010	C00002_C00009 ligase
RP00024	C00025_C00064 main
RP03826	C00002_C00169 trans
RP05695	C00001_C00025 leave
RP06217	C00064_C00169 main
RP10992	C00169_C00288 leave

Enzyme

6.3.5.5

Pathway

rn00240	Pyrimidine metabolism
rn00250	Alanine, aspartate and glutamate metabolism
rn01100	Metabolic pathways

Orthology

K01954	carbamoyl-phosphate synthase [EC:6.3.5.5]
K01955	carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
K01956	carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
K11540	carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K11541	carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (568)   
   KEGG PATHWAY (6)   
   KEGG MODULE (562)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (15)   
   KEGG ENZYME (3)   
   KEGG REACTION (1)   
   KEGG RPAIR (7)   
   KEGG RCLASS (3)   
   SABIO-RK (1)   
Gene (5009)   
   KEGG ORTHOLOGY (5)   
   KEGG GENES (5004)   
All databases (5601)   

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