KEGG   REACTION: R00709Help
Entry
R00709                      Reaction                               

Name
isocitrate:NAD+ oxidoreductase (decarboxylating)
Definition
Isocitrate + NAD+ <=> 2-Oxoglutarate + CO2 + NADH + H+
Equation
RPair
C00003_C00004 cofac [RC:RC00001]
C00026_C00311 main [RC:RC00114]
C00011_C00311 leave [RC:RC02801]
Enzyme
1.1.1.41        1.1.1.286
Pathway
Citrate cycle (TCA cycle)
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
Module
M00009  
Citrate cycle (TCA cycle, Krebs cycle)
M00010  
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Orthology
K00030  
isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
K17753  
isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]

DBGET integrated database retrieval system