| Entry |
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| Name |
acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming);
3-Carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating)
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| Definition |
alpha-Isopropylmalate + CoA <=> Acetyl-CoA + 3-Methyl-2-oxobutanoic acid + H2O
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| Equation |
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|
 |
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| RPair |
| C00010_C00024 main | | C00141_C02504 main | | C00024_C02504 main | | C00001_C02504 leave |
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| Enzyme |
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| Pathway |
| Valine, leucine and isoleucine biosynthesis | | Pyruvate metabolism | | Metabolic pathways | | Biosynthesis of secondary metabolites | | 2-Oxocarboxylic acid metabolism | | Biosynthesis of amino acids |
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| Orthology |
| 2-isopropylmalate synthase [EC: 2.3.3.13] |
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