KEGG   REACTION: R01454Help
Entry
R01454                      Reaction                               

Name
Cholesterol:oxygen oxidoreductase (side-chain-cleaving)
Definition
Cholesterol + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 20alpha-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
Equation
Comment
first step of R02724 (R01454+R04854+R03933)
RPair
C00001_C00007 cofac
C00187_C05500 main [RC:RC00521]
C00007_C05500 leave
Enzyme
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Module
M00107  
Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
Orthology
K00498  
cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]

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