KEGG   REACTION: R03933Help
Entry
R03933                      Reaction                               

Name
20alpha,22beta-Dihydroxycholesterol,ferredoxin:oxygen oxidoreductase (side-chain-cleaving)
Definition
20alpha,22beta-Dihydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 4-Methylpentanal + Pregnenolone + 2 H2O + 2 Oxidized adrenal ferredoxin
Equation
C05501 + C00007 + 2 C00662 + 2 C00080 <=> C02373 + C01953 + 2 C00001 + 2 C00667
Comment
RPair
C00001_C00007 cofac
C01953_C05501 main [RC:RC01029]
C02373_C05501 main [RC:RC01030]
Enzyme
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Module
M00107  
Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
Orthology
K00498  
cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]

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