KEGG REACTION: R04854

REACTION: R04854

Entry

R04854 Reaction

Name

20alpha-Hydroxycholesterol:oxygen oxidoreductase (side-chain-cleaving)

Definition

20alpha-Hydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 20alpha,22beta-Dihydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin

Equation

C05500 + C00007 + 2 C00662 + 2 C00080 <=> C05501 + C00001 + 2 C00667

Comment

second step of R02724 (R01454+R04854+R03933)

RPair

RP00013	C00001_C00007 cofac
RP04469	C05500_C05501 main
RP12442	C00007_C05501 leave

Enzyme

1.14.15.6

Pathway

rn00140	Steroid hormone biosynthesis
rn01100	Metabolic pathways

Orthology

K00498

cytochrome P450, family 11, subfamily A (cholesterol monooxygenase (side-chain-cleaving)) [EC:1.14.15.6]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (27)   
   KEGG PATHWAY (4)   
   KEGG MODULE (23)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (9)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
   KEGG RPAIR (3)   
   KEGG RCLASS (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (23)   
All databases (68)   

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