KEGG   Acanthamoeba castellanii: ACA1_253160
Entry
ACA1_253160       CDS       T02667                                 
Name
(RefSeq) leucine rich repeat domain containing protein
  KO
K08844  leucine-rich repeat kinase 2 [EC:2.7.11.1]
Organism
acan  Acanthamoeba castellanii
Brite
KEGG Orthology (KO) [BR:acan00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:acan01001]
    ACA1_253160
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:acan04131]
    ACA1_253160
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:acan04147]
    ACA1_253160
Enzymes [BR:acan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     ACA1_253160
Protein kinases [BR:acan01001]
 Serine/threonine kinases: TKL group
  LRRK family
   ACA1_253160
Membrane trafficking [BR:acan04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    ACA1_253160
Exosome [BR:acan04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   ACA1_253160
SSDB
Motif
Pfam: Myotub-related PK_Tyr_Ser-Thr COR Pkinase LRR_4 LRR_8 Roc LRR_1 PH Ras PH_11 LRR_9 MMR_HSR1 Ndufs5 FeoB_N
Other DBs
NCBI-GeneID: 14923273
NCBI-ProteinID: XP_004367596
UniProt: L8HAV9
Position
Unknown
AA seq 2402 aa
MKRNSPFLNFSHLTRLVWAEQKEVLAEGFLQKHSPNKALVSRWQTRHFVLTPSTLAYYKK
QSDATPKGVVELSQVCNVVLKTASRALRESPGQETGSGSSSPGKKAVFEVVTLSGRTYVL
AADTIDGARRWVEVLLFTIGELNNRAPVVSAPTFRTTATTKSPGDGMPESEEQESESSNA
AKRSAAEWTLLSGERLLTKQENVLMSHHSLSEGRWGQLHMTLYRFIFSTKDQTDSVPLGL
VMRAEPAKHEERGLSGYLVVCKDFRTISLFFLHPEALETMSSLFKHVLFPPKIRGLYAFH
NKEKYSLRSEVVGWPLYQINQEYERQQLDDNAWRVTHFNKTNSLAHLPNQFIVPAAISDD
MIGQLGDGQLKWQRWVIALCWSNTKSMARGCLLRCSEFMMGPGSGVATAASLLEGREAGG
TTSKRIAAGGGPQGGKQSMLEHVLTLYHAAEALHVYSTTSLRKKLFVLGSETSAGTTELV
QVDAGTISFHTTKLLSPAAIENSLQKLANLVSSFDTSRFERAQHDDTITNSGGCSSAPAT
SGADKVTLQQMKTAWRESLDDTQWLKGVRLLLETTSEIVNLIIDGEPVLVQSADGGDAVP
QVVSLAQVCLDPYFRTTAGFCFLIEKEWMACAHKWGQQQKAKYQPKQYSHMFVQFIDAVW
QLWDSAPTAFEFDSSLLLFLLESVYSARFGSFLVDRQRDRLKGKLLLSSNTISVWSYIDA
NARAFAHDRYNRLDATVMIPLLPRPDQVKLWTGQPAQDEPTTRLSLRNRALHCVPSMVMT
PAFARLASLDLAHNFISTVPLSLSALTGLESLDLSHNLMAGSLPAQLAEALSLLTQLVHL
NLAHNALCDLSALPSQQLQALEELDVSHNGLTAIPAHVVHLTRLRRLSLAGNAFNGEGKK
GQLEVVHSLTSLTSLNLAENEIASLSPRFFNLTRLEHLDLAGCGLTKLPMGIGHLAKLRV
LRISNNPDLRGFPSDFWTLSSLEELYARNCLGWGDASTPEAAAGGILPQLPLNLARRKRA
TTKFPASPDKLDAMMAILPAQFGQLTQLKCLDLSHNGISGIPAVCFMGLTQLEKLWLGGN
TLISLGVDIGAMLSLRELHLSHNRLTALPPEIASLKQLKVLNVEDNALVELPAHLSTIPI
VAMGSSSILAYLGQLLNGQQACYRMKLMFVGQENVGKTSLLNALKRREKRKLAGSKLLRL
GDDDTGAAPLSTDGIDINTWHMTMPWGSSAPQVELSAWDFAGQEIYYATHRFFLSEHSLY
LAVFNLLTSDQSHIDYWLQSIRTAAGDSPVLIIGTHAEDERCTDEYLTQTHNQLARRYGE
RFPNVLGIHFVSCTTGKGLDQLLTNLQSIIAKQEHVGQAVPSNYLELEKVLASQAKERVP
PIVAWSEYRTLARLCLIEHEHDLLTATSLLHNFGSLVHFPNDDKLKEVVILEPQWLMNVM
STVVSTKHNYCRNGVMAHSALPHIWKAPDFPSEVHPFILSLMERFELSFPVGAHIHKLGG
YASSLRPSAGSGAESPTSADEGLYLIPSLLPEARPAQFTDHWPPHTYVGESLFGRVYHFE
FIPKGFMGRLIIRLLAFPLAAQLYWRHGVLAQIGKEKILLELIPDSLQLQITVRTELKGE
QMSNLSWLIFAAVDALVKEWYNLNAKVLVPCSHCMSLGLKSPFMFPMEKCQQAATTPGQS
ILLCPKGTYLGEPVAIKELKSAEIDGFDTLGLNVDAESRRLTFEEFRHEVWIMSGLAHPN
LVGLKGFCMQPPCIVTELVEAGSLFDFLSDPAKNKVLDWALRLKIAKDIAKGCAFLHNTS
PPVMHRDLKSPNILLADLTPEAAVVAKLCDFGVSLSADTTAGRKVDCPVWLAPEILEKKP
YSEKADVYSLGVIFWELLTKEQFFGEVKFMALLEDMVKEGKRPPIPDSCIPSYRQLIEQC
WAQDPNQRPSCKEIVERIEGIIRGVYDASAETDFKARRSAEAARRQQREQRLDSTKKEKM
RAMQMVSIRSMMSAEPKKKLLTQSIKDMAVSRCSKTDIIEFMEEFLKLRKESLLLAAAVK
DNDDADGNYHLKAEVDNNKAEQERAWIDHFLARLNDDKAHAMPPPPLRVSTDAAPAHHHH
QPSKPPMASATSAQASDTAGIETSVSAGATSAEATASAGATSAQDVEAEEAAAVAEKRGL
MVSQVLRDRVNSPSQPRVRSFHAAAPPPLQHRSRTSSGGGNEWRKSTRVSSGASPQLPQQ
MTESSPGSRRSFLGQAALTSSAPSLPTHTPLASPSSPLQPQSPLAAAASLSAPSSPSWGA
VPAARARPAKKAVAASEPSSSEADSPQWGRAPKFAAASADGDRQSEKEARREKKQKEKRA
KKKKEKKEEQKRKEEEEEEEEEEERVQKAKRSDTVAGMRKTLITIEKDLADVLADFEKEL
NS
NT seq 7209 nt   +upstreamnt  +downstreamnt
atgaagagaaactcgcctttcctcaacttttctcaccttacgcgacttgtgtgggctgag
cagaaggaggtgctcgccgagggcttcctgcagaaacactcccccaacaaagcactcgtc
tcgcgatggcagacgcggcactttgtcctcacaccctccacactcgcctactacaaaaag
caaagcgacgcaacgcccaagggcgtggtcgagctgagccaggtctgcaacgtggtgctt
aagacggccagccgcgcgctacgagagagcccaggacaggagacgggctccggcagcagc
agtccgggcaagaaggcggtgtttgaggtggtgacgctgagcggccgcacctacgtgctg
gcggcggacaccatcgacggcgcgcgacggtgggtcgaggtgctcctcttcaccatcggc
gagctcaacaatcgagcaccggtcgtctctgcgcccaccttccgcaccaccgccaccacc
aagtctccgggcgatggaatgcctgagagcgaggagcaagagagcgagagcagcaacgcc
gcaaagaggagcgctgccgagtggacgctgctgtcgggcgagcgattgctgaccaagcag
gagaacgtgctcatgtcgcaccactcgctgagcgaaggccgctggggccagttgcacatg
accctctaccgcttcatattctccaccaaggaccaaaccgattcggtgccgctggggctg
gtcatgcgagccgagccggccaagcacgaggagagaggcctgtcgggctacctggttgtt
tgcaaggacttccgcaccatctcgctcttcttcctccacccggaggcgctcgagaccatg
agctcgctcttcaagcacgtcctcttcccgcccaagatcaggggcctgtacgcgtttcac
aacaaggagaagtattcgctccggtcagaggtggtgggctggccgctgtaccagatcaac
caggaatacgaacggcagcagctcgacgacaatgcctggcgggtcacacacttcaacaag
accaacagcttggcccacctgcccaaccagttcatcgtacccgccgccatttccgatgac
atgattggccaattgggcgatgggcaacttaagtggcagcggtgggtgatcgccctgtgc
tggagcaacaccaagtccatggcgcgcggctgcctgctccgctgctcggagttcatgatg
ggtcccggcagcggtgtagcgacggcggcgtcgcttttggagggccgtgaggcgggtggc
acgaccagcaagcgcatcgctgcgggcggcggcccgcagggcggcaagcagagcatgctg
gagcacgtgctgacgctctatcacgccgccgaggccctgcacgtctacagcaccacctct
ctgcggaagaagctgttcgtgctcggctccgagacgtcggccggcacgactgaactcgtg
caagttgatgcgggcacgatctcatttcacacgacgaagctcctctcacccgcggcgatc
gagaacagcctgcagaagctggccaacctcgtgagctcgttcgatacgtcgcgcttcgag
cgcgcacaacacgacgacaccatcacaaacagcggcggttgcagcagtgcgcctgcaacc
agcggcgcggataaggtcacactgcagcagatgaagaccgcgtggcgggagtcgctcgac
gacacccagtggctcaagggcgtccggctgcttctcgaaaccacgtccgagatcgtcaac
ctgatcatcgacggagagccagttctcgttcagagcgccgatggtggtgacgccgtgccg
caggtggtcagtctcgctcaggtgtgcctggacccgtacttccgtaccacggccggcttc
tgcttcctgatcgagaaggagtggatggcctgcgcgcacaagtggggccagcagcagaag
gccaagtaccagccgaagcagtactcgcacatgtttgtgcagttcatcgacgcagtgtgg
caattgtgggattcggcgcccactgcgtttgagttcgactcgtcgctgctcctcttcctg
ctcgagtccgtgtacagcgctcgcttcggctcgttcctggtcgacagacagcgcgaccgc
ttgaagggaaagctgctcctctcgtccaacaccatctctgtgtggtcctacatcgacgcc
aacgcgcgcgcgttcgctcatgaccgctacaaccgcctcgatgccaccgtcatgatcccc
ctgctgccacgacccgatcaagtgaagctttggactggccaaccggcgcaagacgaaccg
acgacgaggctgagcttgcgcaaccgcgccctccattgcgttccgtcgatggtcatgacg
ccggccttcgccaggcttgcgtcgctcgacctcgcgcacaacttcatcagcacggtcccg
ctcagcctctccgcgttgacgggcctcgagtcgctcgacctctcgcacaacctgatggcc
ggcagcctgcccgcacagctggccgaagcgctgtcactgctcacccagctcgtccacctc
aacctggcccacaacgcgctgtgcgacctgtcggcgctgccctcgcagcaactccaggcc
ctcgaggagctggacgtgtcgcacaatgggctgaccgccatccccgcccacgtagtgcac
ctcacccgactgcgccgcctttccctggccggcaacgccttcaatggcgaaggcaagaaa
ggtcagctggaggtggtccattcgctgacatcgctcacgtcgctcaacttggcggagaac
gagattgcctcgctgtcgccgcgcttcttcaacctgacccgcctcgagcatctggacctc
gccggctgcgggctcaccaagctcccgatgggcatcggccacctggccaagcttcgcgtc
ctgcgcatctccaacaatcccgacctgcgcggcttcccgagcgacttttggaccctatcc
tccttggaggagctctacgcacggaactgcctaggctggggcgatgcgagtacgccggaa
gcggccgccggaggcattttgcctcagcttccgctcaacctcgcacgacgcaagcgagcc
accaccaaattccctgcctcgcctgacaagctcgatgcgatgatggcgattctgcccgcg
caattcggccagctcacgcagctcaagtgcctcgacctctcgcacaacggcatctcggga
attccggcggtgtgcttcatgggcctgacccagctcgagaagctgtggctgggcggcaac
acgctcatctcgctcggcgttgacatcggcgccatgttgtcgctccgcgagctccacctg
agccacaaccggctcaccgcgctgccgccggagatcgccagcctgaagcagctcaaggtg
ctcaacgtcgaggacaacgcgctggtcgagctgccggcccatctgagcaccatcccgatt
gtggccatgggctcgtcgagcatcctggcgtacctggggcagctgctgaatggccagcag
gcgtgttaccgcatgaagctcatgtttgtcggtcaggagaacgttgggaaaacgtcgctc
ctcaacgcgctcaagaggagggagaagcgaaagctcgccggttccaagctgctgcgactg
ggcgatgacgacactggcgctgctccgctgtctaccgacggcatcgacatcaacacgtgg
cacatgaccatgccctggggctccagcgctcctcaggtcgagctctcagcttgggacttt
gcgggccaggagatctactatgccacgcatcggttcttcctctccgagcactcgctgtat
ctggccgtgttcaacctcctcacttccgaccaatcgcacatcgactactggctgcagtcc
atacgtacggccgccggagactcgccggtgctcatcatcggcacgcacgccgaggacgaa
cgatgtaccgacgaatacctgacccagacgcacaaccagttggcgcggcgatacggcgag
cgatttccgaacgtgctgggcatccactttgtgagctgcacgacgggcaagggcctggac
cagctcctgaccaacctccagtccatcatcgccaagcaggagcacgtgggccaggccgtg
ccgtccaattacctcgagctggagaaggtcctggcgagccaggccaaggagcgcgtaccg
cccatcgtcgcctggagcgagtaccgcacgctggcgcggctgtgcctcattgagcacgag
cacgacctgctcaccgccacctcgctcctccacaacttcggatcgctcgtgcatttcccg
aacgacgacaagctgaaggaggtggtcatccttgagccccagtggctcatgaacgtcatg
tccaccgtcgtctccaccaaacacaactattgccggaatggcgtgatggcccattcggcg
ctgccccacatatggaaggcgccggactttccgtccgaggtccaccccttcattctctcg
ctgatggagcggttcgagctctcgttcccggtcggcgcgcacatccacaagctcggcggc
tacgcctcttccctccgaccctcggccggctccggcgccgagagcccgacatccgccgac
gagggcctctacctcatcccctcgctgctgcccgaagcgcggccagcccagttcaccgac
cattggccaccgcacacatatgtgggcgagtccctctttggtcgcgtttaccactttgag
ttcatccccaagggattcatgggacggctgatcatccggcttcttgcgttccctctcgcg
gcgcagctctactggcgtcacggcgtgctggcccagatcggaaaggagaaaatcctgctg
gagctgataccggacagcctgcagctgcagatcacggtgaggaccgagctcaagggcgaa
cagatgtcgaacctgtcgtggctcatcttcgccgctgtggacgccctcgtcaaggagtgg
tacaacctcaacgccaaggtgttggtgccgtgctcgcactgcatgagcctcggcctcaag
agccccttcatgttcccgatggagaagtgccagcaggccgccaccacgcccggccaatcg
atccttctctgtcccaaaggtacctacctgggcgaaccggtggccatcaaggagctcaag
agcgccgagatcgacggcttcgatacgttgggtctcaacgtcgacgccgaatcgcgacgg
ctcacctttgaagagtttcgacacgaagtctggatcatgagtggactggcccatcccaat
ctggtgggcttgaaggggttctgcatgcagccgccctgcatcgtgacggagctggtggag
gccggctccctgtttgacttcctctccgatcccgccaagaacaaggtcctcgactgggcc
ctccgcctcaagatcgccaaagacatcgccaagggatgtgcgttcctacacaacacatcg
ccgccggtgatgcaccgtgacctgaagagccccaacatcctgttggcggaccttactccc
gaggcggcggtggtggccaagctgtgcgactttggcgtctcgctctccgccgataccaca
gccggccgcaaagtcgactgccctgtgtggcttgctccggagattctggagaagaagccc
tactcggagaaggccgacgtctactcgctcggggtgatcttctgggagctgctcaccaag
gagcagttcttcggcgaagtcaagttcatggccctcctcgaggacatggtgaaggaggga
aagcgtccgcccattccggactcgtgcatcccttcgtaccgtcagctcatcgaacagtgc
tgggctcaggacccgaaccagcggccgtcgtgcaaggagatcgtggagcggatcgaaggg
atcatccggggcgtgtacgacgccagcgccgagaccgacttcaaagcccgccggtcggcc
gaggccgcacggcgacaacagcgcgagcagcggctcgactccaccaagaaggaaaaaatg
cgagcaatgcagatggtcagcattcggtcgatgatgtcagccgagcccaagaagaagctg
ctgacccagtcgatcaaggacatggccgtctcgcggtgctccaagaccgacatcatcgag
ttcatggaggagttcctcaagctgcgcaaggagagcctcctcctggctgccgccgtcaag
gacaacgacgacgctgacggcaactaccaccttaaggccgaggtcgataacaacaaggcc
gagcaggagcgggcgtggatcgaccacttcctggcgcggctcaacgacgacaaggcccac
gccatgcccccgccgcccctgcgcgtcagcaccgatgccgcgccggcccaccatcaccac
cagccatcgaagccgcccatggccagtgccacgtcagcacaggcaagtgacacggctggt
atcgagaccagtgtcagtgccggcgccacgtcagcagaggccacggccagcgctggtgcc
acgtcagcacaagacgtggaggcggaggaggcggcggcagtggcggagaagagagggctg
atggtgagccaggtgctgcgggatcgcgtcaactcgcccagccaaccgcgggtgcggagc
ttccacgcggccgcgccgccaccccttcaacatcgctcgcgcaccagctccgggggcggc
aacgaatggcgcaagagcacccgagtcagcagcggtgcgtcgccgcagctgccgcagcag
atgactgaatcttcgcccggctcccgccgctcgttcctcggccaggccgccctcacctcc
tccgcgccctccctgcccacccacacgccgctggcctcgccgtcgtcgccgttgcagccg
caatcaccgttggcggcggcggcgtcgctgtcggccccgtcgtcgccgtcgtggggtgcg
gtaccggcggcccgggcaaggccggccaagaaggcggtggcggccagcgagccgtcgtcg
tcggaggctgactcaccgcagtggggccgcgcgcccaagttcgccgcagccagcgccgac
ggcgaccgccagagcgaaaaggaggcgcgccgggagaagaaacagaaggagaagcgagcg
aagaagaagaaagagaaaaaggaggagcagaagaggaaggaggaagaagaagaggaggag
gaggaggaggaacgggtgcagaaggcgaagaggagcgatacggtggcgggcatgcgaaag
acgctgatcaccatcgagaaggatctggccgacgtcctcgccgacttcgagaaagaactc
aacagctga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (99)   
   KEGG ORTHOLOGY (1)   
   RefGene (95)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (15)   
   Pfam (15)   
All databases (124)   

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