KEGG   Anolis carolinensis (green anole): 100562345Help
Entry
100562345         CDS       T01608                                 

Gene name
pik3ca
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
acs  Anolis carolinensis (green anole)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:acs00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100562345 (pik3ca)
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    100562345 (pik3ca)
   04370 VEGF signaling pathway
    100562345 (pik3ca)
   04630 Jak-STAT signaling pathway
    100562345 (pik3ca)
   04068 FoxO signaling pathway
    100562345 (pik3ca)
   04070 Phosphatidylinositol signaling system
    100562345 (pik3ca)
   04150 mTOR signaling pathway
    100562345 (pik3ca)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100562345 (pik3ca)
  Cell growth and death
   04210 Apoptosis
    100562345 (pik3ca)
  Cellular commiunity
   04510 Focal adhesion
    100562345 (pik3ca)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    100562345 (pik3ca)
  Endocrine system
   04910 Insulin signaling pathway
    100562345 (pik3ca)
   04914 Progesterone-mediated oocyte maturation
    100562345 (pik3ca)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100562345 (pik3ca)
Enzymes [BR:acs01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100562345 (pik3ca)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
3
AA seq 1068 aa AA seqDB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNIESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGESSAKSLWAINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMQVLDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEDHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLHAICTRDPL
SEITEQEKDFLWSHRHYCVNMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPPIKPELAME
LLDCNYPDPMVRSFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt NT seq  +upstreamnt  +downstreamnt
atgcctccaaggccatcatctggggaactatggggcatccacttaatgccaccaagaatc
ctagtggaatgtcttctaccaaatggtatgatcgtgactttagaatgcctccgtgaggcc
actttgttaaatattaaacatgaactctttaaagaagctagaaaataccccctctatcaa
ctccttcaagatgagtcttcttacatttttgtaagtgttacacaagaagcagaaagagaa
gaattttttgatgaaacacggcgactatgtgacttacggctcttccagccctttctaaaa
gttatagagccagtaggcaacagggaagagaagattcttaatcgtgagatcggttttgct
attggcatgcctgtctgtgaatttgacctggtgaaagatccagaagttcaagacttcaga
agaaacattcttaatgtttgtaaagaagcagtagatttgcgggatgttaatgcaccccat
agtagagcattgtacgtctgtcccccgaacatagaatcttcgcctgagttgcccaagcac
atatacagtaaacttgataaagggcaaataatagtggtgatatgggttattgtctcccct
aacaatgacaagcagaagtacaccttaaaaataaatcacgactatgtaccagaacaagta
attgctgaagcaatcaggaaaaaaacacgaagcatgttgctgtcgtcagaacagctaaag
ctctgtgtgttggagtaccaggggaagtatattttaaaagtatgcggttgtgatgaatat
ttgctagaaaaacaccccctgagtcagtataagtatattcggagctgcatcatgcttggt
cgaatgcccaacttgatgctgatggctaaggaaagtctttatacccaactgccattggat
accttcacaatgccatcttattctcgacgtatctctacagctacaccatacatgaatgga
gaatcttctgcaaaatctctctgggctattaacagtaatcttagaatcaagattctctgt
gccacttatgtaaatgtaaatattcgggacattgacaagatctatgtccggactggaata
tatcatggtggagaaccattgtgtgataatgtgaatacgcagagagtaccttgctccaat
cccagatggaatgaatggctgcaatatgaaatgcaagttcttgatctcccacgtgctgct
cggctttgcctttctatctgctctgtcaaaggcagaaagggagcaaaggaggagcactgc
ccattggcgtgggggaatattaacatgtttgattacacagacacgcttgtttctggcaaa
atggctctgaatctgtggcctgtacctcatgggttggaagacctgctcaatcccattgga
gtcactggatcaaatccaaataaggaaactccctgtttggagttagaatttgattggttt
agcagtcctgtaaagtttcctgacatgtcagtaattgaagaccatgccaattggactatc
tctcgagagctaggatttaactacagtcatgctggactgagtaatagactagctagagac
aatgaattaagagagagcgataaagagcaactccatgcaatctgcactcgagaccctctg
tctgaaataactgaacaagaaaaggactttctttggagccacaggcactattgtgtcaat
atgccagaaattcttcctaagctgcttttgtctgttaaatggaactcaagagatgaagta
gcccagatgtactgcttgataaaagactggcctcccatcaagcctgaactagcaatggag
cttttggattgtaattacccagatccaatggtgcgatcatttgcaattcggtgtttggag
aaatacttgacagatgacaaactctcacagtatttgattcagttggtacaggttctgaaa
tatgagcaatacttggataatctgttggtgaggtttttactcaagaaggcactgaccaat
cagagaatagggcacttcttcttttggcatctaaagtctgaaatgcacaataaaaatgtg
agccagaggtttggtctgcttttggagtcctactgccgtgcatgtgggatgtacctgaaa
cacctgagcagacaagtggaagctatggaaaaactgattaacctcacagacatccttaaa
caagagaaaaaggatgaaacacaaaaggtacagatgaaattccttgtggaacaaatgaag
cggccagacttcatggatgcattgcaaggctttatatcccctctcaatcccgctcatcag
cttggaactcttaggctggaggagtgcagaattatgtcctctgctaagagaccattatgg
cttaattgggaaaacccagatattatgtctgagctgctgtttcagaacaatgagatcatc
tttaaaaatggggatgatctacgtcaggatatgctcacacttcaaataattcgaattatg
gaaaacatttggcaaaatcaaggccttgatcttaggatgttgccttatggttgtttatct
attggtgactgtgtgggactcattgaggtagtaagaaattcacatacaatcatgcagatc
caatgcaaaggtggtcttaaaggtgcactgcagttcaacagtcatacattacatcagtgg
ctcaaagataagaacaagggggaaatgtatgatcctgctattgatttgtttacacgctct
tgtgctggctattgtgtagctactttcatattgggaattggagatcgccacaatagcaat
attatggtgaaagatgatgggcagctgtttcatatcgattttggacacttcttggatcac
aaaaagaagaagtttggctacaaacgagagcgtgtgccatttgtcttaacacaagatttc
ttgatagtgattagtaaaggagcccaagaatgtactaaaacaagggaatttgagagattt
caagaaatgtgctacaaggcatatctagcaattcggcagcacgccaatcttttcataaac
ctcttctccatgatgcttggatcggggatgccagaactgcagtcttttgatgacattgca
tatattcgcaaaactcttgctttagacaaaactgaacaggaagcacttgagtatttcatg
aaacagatgaatgatgctcatcatggcggatggacaacaaaaatggactggatcttccac
acaatcaaacaacatgccttgaactga

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