KEGG   Aeromonas sp. CU5: CK911_03545
Entry
CK911_03545       CDS       T05327                                 
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
aem  Aeromonas sp. CU5
Pathway
aem00280  Valine, leucine and isoleucine degradation
aem00640  Propanoate metabolism
aem00785  Lipoic acid metabolism
aem01100  Metabolic pathways
aem01110  Biosynthesis of secondary metabolites
aem01210  2-Oxocarboxylic acid metabolism
Module
aem_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:aem00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    CK911_03545 (pdhA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    CK911_03545 (pdhA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    CK911_03545 (pdhA)
Enzymes [BR:aem01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     CK911_03545 (pdhA)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: ATL91970
UniProt: A0A291TFX5
Position
769569..770657
AA seq 362 aa
MTHVDIPFLRYLDAEGCPVATLPTWLDKAILHTFYRNMVMVRSYDKKAIALQRTGKLGTF
PSHLGAEAVGIGIGLAMQPQDVYVPYYRDMPTLYVRGVPMEKNLQYWGGDERGSYSLKPD
GTPSEDLPICVPIATQITHACGIASAFKLRNQPRVAVVTIGDGGTSKGDFLEGLNCAGVW
HLPMVIIVNNNQWAISVPRKLQSSAPTLAQKGIGAGVRSLQVDGNDVVAVYDAARSAVER
ARSGKGPTLIEAVSYRLGDHTTADDATRYRDGAEVEAAWAKEPVKRLRQFMHSKGWWDEE
QEQSLLAEATREVEQAVARYEAMAPQPPEAMLDYHYASLPAELLPQRERVIAKGMKQEVG
HE
NT seq 1089 nt   +upstreamnt  +downstreamnt
atgacccatgtcgacatccctttccttcgttatctcgatgcggaagggtgcccggtcgcc
accttaccgacctggctggacaaggcgatactgcacaccttctaccgcaatatggtgatg
gtgcgcagctatgacaaaaaagcgattgcgctgcaacgaaccggcaaactcggtactttt
ccctcccatctcggcgcagaagccgtggggattggcattggtctcgccatgcagccgcag
gatgtctacgttccctactatcgggacatgcccaccctctatgtgcggggcgtaccgatg
gagaagaacctgcaatattggggcggtgacgagcgggggagttattctctcaaacccgat
gggactccctctgaagatctccccatctgcgtccccatcgccacccagatcactcacgcc
tgcggcattgcgtctgccttcaaactgcgtaatcaaccgcgtgtcgccgtagtcactatc
ggcgatggcggcacctccaagggggattttctggaggggctcaactgcgccggtgtctgg
cacctgccgatggtcatcatcgtcaacaacaaccagtgggccatctcggtgccacgcaag
ctgcaatcgagcgctcctacgctggcccagaaggggattggcgccggggtgcgcagcctg
caagtggatggcaacgatgtggtcgcggtctacgatgctgcccgcagtgccgtcgaacgg
gcccgcagcggcaaggggccgaccctgatagaagcggtcagttatcgtctcggcgatcac
accacggccgacgatgccactcgctatcgagatggggccgaggtcgaggccgcttgggcg
aaagagccggtcaagcggctgcgccagtttatgcatagcaaaggctggtgggatgaagag
caggagcagagcctgctggcggaagccacccgggaggtagagcaggcggtcgcccgctat
gaggcgatggcgccccagccgccggaggcgatgctcgattatcactacgccagcctgccc
gccgaactcttgccccagcgcgagcgagtgattgccaaggggatgaagcaggaggttggc
catgagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (54)   

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