KEGG   Aspergillus fumigatus: AFUA_2G03700
Entry
AFUA_2G03700      CDS       T01017                                 
Name
(RefSeq) HMG-CoA reductase
  KO
K00021  hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
Organism
afm  Aspergillus fumigatus
Pathway
afm00900  Terpenoid backbone biosynthesis
afm01100  Metabolic pathways
afm01110  Biosynthesis of secondary metabolites
Module
afm_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:afm00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    AFUA_2G03700
Enzymes [BR:afm01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.34  hydroxymethylglutaryl-CoA reductase (NADPH)
     AFUA_2G03700
SSDB
Motif
Pfam: HMG-CoA_red HPIH Sterol-sensing Patched
Other DBs
NCBI-GeneID: 3506671
NCBI-ProteinID: XP_749502
UniProt: Q4WHZ1
Position
2:984934..988503
AA seq 1130 aa
MATSLITRKLRSAEATNDVEPGWLKRQVTGVLQSISSHACQHPIHTIVVIALLASTTYVG
LLEGSLFDSVRNSRNIAGQVDVDTLLQGSRNLRLGESTSWKWQVEDSLASQDYTGVNHLA
LTTFIFSDSLSKSSSIAPAATELPIPSNASAQPVPFTPNLFSPFSHDSSLAFTLPFDQVP
QFLKAVQEIPDTSSDEDDGEQKKWIMRAARGSAYGSGGAIKLWLADAWGSFVDLIKHAET
IDIVIMTLGYLSMHLSFVSLFFSMRRLGSNFWLAATVLFSGVFAFLFGLLVTTKLGVPIN
VLLLSEGLPFLVVTIGFEKPIILTRAVLTAAADNRGRAGQASSSTTKSIQDSIQTAIKEQ
GFEIIRDYCIEIAILIAGAASGVQGGLRQFCFLAAWILFFDCVLLFTFYTTILCIKLEIN
RIKRHITLRKALEEDGITHRVAENVASSNDWPLTESESSNKTSIFGRKLRSSSVRRFKIL
MVGGFVLVNVVNLSTIPFRDSSQGAGLPLLSRVSNVFAPTPIDPFKVAENGLDSIYVSAK
SQMMETVVTVIPPIKYKLEYPSVYYAALGESRTFDIEYTDQFLDAVGGRVIESLLKSIED
PIISKWIIAALTLSIILNGYLFNAARWSIKEPEVAPVPAAPTVAVVEAKKEYPKIDLNPD
TPKRSLEECEAFLKEKRAAYLSDEELIELSLRGKIPGYALEKTMENEDLMSRVDAFTRAV
KIRRAVVARTPATSAITGSLECSKLPYKDYNYTLVHGACCENVIGYLPLPLGVAGPLTID
GQSYFIPMATTEGVLVASTSRGAKAINAGGGAVTVLTGDGMTRGPCVGFPTLARAAAAKV
WIDSEEGRSILTAAFNSTSRFARLQHLKTALAGTYLYIRFKTTTGDAMGMNMISKGVEKA
LHVMATECGFDDMATISVSGNFCTDKKAAAINWIDGRGKSVVAEAIIPGDVVRSVLKSDV
NALVELNTSKNLIGSAMAGSVGGFNAHASNIVTAVFLATGQDPAQNVESSSCITTMRNLN
GNLQIAVSMPSIEVGTIGGGTILEAQSAMLDMLGVRGSHPTNPGDNARQLARIVAAAVLA
GELSLCSALAAGHLVRAHMAHNRSAATTRTSTPVSAAVSAARGLTMSSSE
NT seq 3393 nt   +upstreamnt  +downstreamnt
atggctacctctctgattacaaggaagcttcgttcggcagaagccacgaacgatgtcgaa
ccgggatggctaaagcgtcaggtcactggcgttttacagtccatctcgagtcacgcttgt
cagcaccctatacacaccattgtggttattgcattgctcgccagtacgacgtacgtcggt
ctccttgaagggagtttgttcgacagcgtcaggaattccaggaatattgcaggtcaagtg
gacgtcgatactctgcttcagggcagccggaatcttcggttgggtgagagtacatcttgg
aaatggcaggtggaggacagtttagcgagccaggactacacgggcgtcaaccatcttgcc
ttaacaaccttcatcttctcggattccctgtccaagtcatcttcaatcgctcctgccgca
acagaattaccgattccttccaatgcctctgctcaaccagtgccatttacacctaacttg
ttctcgcccttctcccatgactcttctcttgcattcaccttgccgtttgatcaggtccca
caatttctgaaagcggtgcaggagatcccggacacctcctccgatgaggacgacggggaa
caaaagaaatggatcatgcgggccgctcgtggctcggcttatggctctggtggtgctatc
aagctctggttggcagatgcgtggggttcattcgtggatttgatcaagcacgcggaaact
attgatattgtcatcatgaccctgggatacctttcgatgcaccttagcttcgtgtccctc
ttcttctcgatgcggcgtctcggctctaacttctggttggctgccacagtcctcttctcg
ggcgtttttgcatttttgtttggtcttctggtcacaacgaagcttggcgtcccgatcaat
gtccttttgctgtccgagggccttccattccttgttgtcactatcggtttcgagaagcca
atcattcttaccagggctgttctcactgcggcagcggacaacaggggcagagctggtcaa
gcttcgtcaagcaccacaaagtccattcaggactctattcagaccgcgatcaaggaacaa
ggttttgagattatccgcgattactgcatcgagatcgccattcttattgccggggccgct
tctggagtccagggtgggttgcgacaattctgttttctcgcggcgtggatcttgtttttc
gactgcgttctacttttcactttctacaccaccatcctctgcatcaaactcgaaattaac
cggatcaagcgccacatcactcttcgcaaagctctggaagaagatggtatcacccatcgg
gtggccgagaatgtcgcttccagtaatgattggcctctgaccgaatctgagagcagcaac
aagactagcatctttgggagaaagctccgctccagcagtgttcgcagattcaagattttg
atggtaggaggttttgtcttggtcaatgtggtgaatctatccaccatcccattccgggac
tcaagccagggtgctggcctacctctactgtctcgtgtctctaatgtgtttgcgcctacg
cccattgaccctttcaaggtcgcagaaaatgggcttgactcaatctatgtctctgcaaag
agccagatgatggagacggttgtgacagtcatccctccaatcaagtacaagcttgaatat
ccttctgtatactacgccgctttgggtgaaagccgcactttcgatatcgagtacaccgat
cagttcctcgacgccgttggcgggcgtgtcatcgagagtcttctcaagagtatcgaagat
cctatcatcagcaagtggatcattgctgctctgaccctgagcattatcttgaacggctac
ttgttcaatgccgctcgctggagcattaaggagcccgaagttgcccctgtccctgccgcc
cccacggtggctgtggtggaagcgaagaaggaataccctaagatcgacttgaaccccgac
actcccaagaggagtttagaagaatgtgaggccttcttgaaagagaagcgagccgcttac
ttgagcgatgaagaattgattgaactttccctgcgaggcaagattcctggctatgcgttg
gaaaagaccatggagaacgaggacctcatgagccgtgtggatgcgttcactagagcggtc
aagatccgtcgagctgttgttgctcgaactcctgccacttccgctatcacaggctctttg
gaatgttcaaagctcccatacaaggattacaactatacccttgtgcacggtgcctgctgt
gagaatgtcattggatatctgccattgcctttgggagtggctggccccttgaccattgat
ggccagagctactttattcccatggctaccacggaaggtgtgctggtggccagcacaagt
cgaggcgccaaggcgattaacgcaggtggtggcgcggtcactgtcctgactggcgacggc
atgactcgtggcccttgtgtcggtttccctactcttgcacgcgcggcggctgctaaggtc
tggattgattcagaagagggtcgaagcattttgactgcggcttttaactctaccagtcgg
tttgcccgccttcaacatcttaagacggctctcgctggcacttatctttacatccggttc
aagaccacaacaggtgacgccatggggatgaatatgatctctaaaggtgtcgaaaaggcg
ctccacgttatggcgactgagtgcggctttgacgacatggctaccatttccgtttctggt
aacttctgtactgacaaaaaggctgctgctattaactggattgacggtcgtggcaagtcc
gtggtggctgaggccatcattcctggtgatgttgtccggagcgtgctcaagagtgacgta
aatgccctggtcgagctcaataccagtaagaacttgattggaagtgctatggccggaagc
gtgggtgggttcaacgctcacgcatcgaacattgtcactgctgttttcttggcaacgggt
caggatcctgcgcagaatgtcgagagcagcagctgtatcacgaccatgagaaacctcaat
ggcaacctccagatcgctgtgtctatgccttccatcgaagttggcacaatcggcggtggc
acgattctcgaagcacaatctgccatgcttgatatgctaggtgtccgtggttcccaccct
accaatccaggtgacaacgctcggcaacttgctcgaattgtcgctgccgctgttcttgcg
ggagagctgagcttgtgctctgcacttgccgccggccaccttgtcagagcgcacatggcg
cacaaccgcagtgctgctacgacacggacttctacccccgtctcagcagccgtgagtgct
gctcggggattgacgatgtcctcctcggagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (28)   

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