KEGG   Aspergillus fumigatus: AFUA_3G08650
Entry
AFUA_3G08650      CDS       T01017                                 
Name
(RefSeq) C1 tetrahydrofolate synthase
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
afm  Aspergillus fumigatus
Pathway
afm00670  One carbon pool by folate
afm01100  Metabolic pathways
afm01240  Biosynthesis of cofactors
Module
afm_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:afm00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    AFUA_3G08650
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:afm04147]
    AFUA_3G08650
Enzymes [BR:afm01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     AFUA_3G08650
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     AFUA_3G08650
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     AFUA_3G08650
Exosome [BR:afm04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   AFUA_3G08650
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH OCD_Mu_crystall Adeno_VII
Other DBs
NCBI-GeneID: 3512153
NCBI-ProteinID: XP_754750
UniProt: Q4WX91
Position
3:2214642..2217724
AA seq 939 aa
MTATKIDGTAIAKSIREGLKAEIAKIQESNPRFKPSLVIFQVGNRSDSSTYVRMKLKAAE
EANILCKIVNFPESISQPEILQEITKANNDPSVHGILVQLPLPSHLSEHTVTSAVADEKD
VDGFGAINIGELAKRGGHPLFVPCTPLAVMDLLKASGVNPAGKEAVVLGRSDIVGSPVSY
LLKNADATVTVCHSKTPDIPRIVKNADIVVAAIGKAEFVKGDWLKPGAVVIDVGINYKPD
PSKKSGQRLVGDVDFEAAVEVASQITPVPGGVGPMTVAMLLKNVVTSAKAYFEKQRDRHV
TPLPLKLVRPVPSDIAISRAQYPKPITQVAAEVGIAPHELEPYGHTKAKISLSVLDRLAH
RRNGRYVLVCGITPTPLGEGKSTTTLGLTQALGAHLNRIVFANVRQPSQGPTFGIKGGAA
GGGYSQVIPMDEFNLHLTGDIHAITAANNLLAAAIETRMFHEATQKDAALYKRLVPVKKG
KREFQPIMFRRLKKLGITKTNPDDLTEEEIRRFARLDIDPQTITWRRVLDVNDRHLRGIT
VGQAPTERGLSRETGFDISVASECMAILALSNSLEDMRERLGRMVVATSKSGDPVTCDDI
GAGGALAALMKDAIKPNLMQSLEGTPVLVHAGPFANISIGASSIIADKLALKLAGTEPDE
DHEAKTGFVVTEAGFDFTMGGERFFNIKCRSSGLSPDCVVIVATVRALKVHGGGPEISPG
APLHEIYRTENTEILRKGCVNLKKHIQNAKMYGVPVVVAINRFETDTEAEIAIVREEAIA
AGAEDAIPANHWAEGGAGAVDLAKGVLAASSKPKDFKLLYDLEGSIQERIERIGKAMYGA
EKVEFSELAQKKVDTYTAQGFSNLPICIAKTQYSLSHDPALKGAPTGFTIPIRDVRLAVG
GGYLYALAADIQTIPGLPTAPGYLNVDIDTETGEIDGLF
NT seq 2820 nt   +upstreamnt  +downstreamnt
atgacggccacaaagatcgatggcacggccattgccaagagcattagagagggattgaaa
gccgagattgcaaagattcaggagtccaatcctcggttcaagccgagtttggtgatcttc
caggtcggcaatcgatcggattcgagcacatatgtgcgcatgaaattaaaggccgctgaa
gaggcgaacattctctgcaagattgtcaactttcctgaatcgatctctcagcctgagatc
cttcaggaaatcacaaaggctaacaacgatccctcggtgcacggcatcctcgtccaactt
cctcttcctagccacctgtccgaacatacagtcacatctgcagttgccgacgaaaaggat
gtcgatggtttcggcgcaataaatattggagagttggccaaacgaggtggccatcctctc
ttcgttccctgcaccccgctggctgttatggacctcctcaaggcaagtggagtaaatccc
gccggcaaagaggcagtggttcttggccgtagtgacatcgtcggaagccctgtcagctac
ctgttgaaaaatgcagacgccaccgtgactgtctgccactccaagacgccggacatcccc
cgcatcgtgaagaacgccgacattgttgttgcagccattgggaaggcagagttcgtcaag
ggcgactggctgaagcctggtgccgttgttatcgatgttggcattaactacaagcctgat
ccttcgaagaagtcgggacagcgtctcgtcggagatgtcgattttgaggccgccgtagag
gtagcttcgcagatcactccagttcctggaggtgttggtcccatgacagttgccatgctg
ctaaagaacgtcgttacttcggccaaggcatactttgaaaagcagcgggacaggcatgtt
acgccgcttcccctcaagctggtccggcctgttccttccgacattgccatctcccgtgct
cagtaccccaagcccattactcaagtcgccgcggaggttggcattgctccccacgagctg
gagccgtacggccacaccaaggctaagatcagtttgagtgttctcgaccgcttggctcac
cgccgtaatggacgttatgtcctggtgtgcggtattactcctacgcctcttggagagggc
aagtccacgactacactcggtcttactcaagcgctgggcgcacacctgaaccggatcgtg
tttgccaatgtccggcaaccgagtcagggtcccacatttggtatcaagggtggcgctgcc
ggtggaggctacagccaggtcattcccatggacgagttcaacctccatctgaccggtgac
attcacgcgattactgctgccaacaaccttctggctgccgccattgaaactcgcatgttc
catgaagccacccagaaggatgctgctctttacaagcgactggtccctgtcaaaaagggc
aagcgcgaattccagcccatcatgttcagaagactcaagaagcttggcattactaaaacg
aaccctgacgatctcaccgaggaagaaatccgccgttttgcgcgccttgacattgatccg
cagacaatcacctggcgccgtgtgttggatgtcaatgatcgccatctccgaggcattacc
gtcggacaggcccctactgaaaggggtctgtcacgcgagacgggctttgacatctccgtg
gccagtgaatgtatggccatccttgcgttgagcaacagtctcgaagacatgcgcgagaga
ttgggacgcatggttgttgccacctctaagagcggggaccccgtgacttgtgacgatatc
ggcgctggaggagccttggccgccttgatgaaggatgctatcaagcccaacctgatgcag
agcttggagggaactccagtgctggtccacgccgggcccttcgccaacatcagtattggt
gccagttctatcatcgctgataaattggcgctgaagcttgccggtactgaacctgatgag
gatcacgaggctaagactggtttcgtagttactgaggccggtttcgacttcaccatggga
ggtgagcgtttctttaacatcaagtgccggtcatctggtctctccccagactgtgtggtc
attgttgccaccgtccgggctctgaaggttcacggtggtgggccagagatcagccctgga
gcgccgctccacgagatttatcgcactgaaaacaccgagattctccgcaagggctgtgtg
aacctcaagaagcacatccagaacgccaagatgtacggagtgccggtggttgtagccatc
aatcggtttgagacggacacggaagccgaaattgctatcgtccgcgaggaggctattgct
gccggtgcggaggatgctattcctgccaatcactgggccgagggaggtgccggagccgtt
gaccttgccaagggagtgttggcagctagctccaagcccaaggacttcaagctcctgtat
gacttagaaggtagcatccaggagcgcattgagcgcattggaaaggccatgtacggtgcg
gagaaggttgagttcagcgagctggcgcagaagaaggtcgacacctacacagcacaaggc
ttctccaatcttccgatctgcatcgccaagacccagtactcattgagtcatgatcccgcg
ctcaagggggccccaacaggctttacaattcccatccgtgatgttcggctagctgttgga
ggtggatatctttacgcacttgcggcagacatccagaccattcccggattgccgactgct
ccgggttatctgaacgttgacatcgacaccgaaaccggggagattgacggcctattctag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (38)   

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