KEGG T00424: AHA

Aeromonas hydrophila subsp. hydrophila ATCC 7966: AHA_2722

Entry

AHA_2722 CDS T00424

Gene name

leuA-2

Definition

2-isopropylmalate synthase (EC:2.3.3.13)

Orthology

K01649

2-isopropylmalate synthase [EC:2.3.3.13]

Organism

aha Aeromonas hydrophila subsp. hydrophila ATCC 7966

Pathway

aha00290	Valine, leucine and isoleucine biosynthesis
aha00620	Pyruvate metabolism
aha01100	Metabolic pathways
aha01110	Biosynthesis of secondary metabolites
aha01210	2-Oxocarboxylic acid metabolism
aha01230	Biosynthesis of amino acids

Module

aha_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Class

Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:aha00620]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine biosynthesis [PATH:aha00290]

SSDB

Motif

Pfam:

HMGL-like LeuA_dimer

Other DBs

NCBI-GI:

NCBI-GeneID:

JCVI-CMR:

UniProt:

Position

complement(3058555..3060213)

AA seq 552 aa
MSFDHRKYRRAPVINLADRQWPNRVLERAPLWCAVDLRDGNQALVEPMTVAQKLQMWALM
VHIGFKHIEVGFPAASQPDFDFVRELIDRNLIPDDVTIQVLVQAREDLIARTFEALKGAK
RAIVHVYNSVNPTQRNYVFNSGREGVKAIAVQGARWVREYAARNSGTEWSFQYSPESFSC
TEVEFAVEVCDAVIDQWRPAARPMILNLPATVEVSTPNVFADQVEWFCRHLKARPEVSIS
IHTHNDRGCGVAAAELAVLAGADRIEGTLLGNGERTGNMDIVTMAMNLYSQGIDPELNLA
DMDAIVATVGACTQIALHPRHPYAGELVYTAFSGSHQDAIRKSLAAEKPDHYWDVAYLPI
DPADLGRSYEAVIRINSQSGKGGVTYLLERDLGLQLPRWLQIDFSRRVQAEAEASSSEIS
PEQIRSLFERHYLEPAHGYRIGRFQLGRDSQESLRLELQTPTGSLQLSGEGEGAITALVN
GWQRQTGMHIDVLDYSEHALSAGTESRAAAYVLLSVDGTRTCGVAIGRDVVSASLQAVIN
GAAQIEALRQSA

NT seq 1659 nt +upstreamnt +downstreamnt
atgagcttcgatcatcgcaaataccgccgtgcccccgtcatcaatctggcggatcgccag
tggcccaaccgggtgctggagcgggcgccgctctggtgcgccgtggatctgcgcgacggc
aaccaggcgctggtcgagccgatgacggtggcgcagaagctgcagatgtgggcgctgatg
gtgcacatcggcttcaagcacatcgaggtgggctttccggccgcctctcagcccgatttt
gacttcgtgcgcgagcttatcgatcgcaatctcattccggacgacgtcaccatccaggtg
ttggtacaggcgcgcgaagatctgatagcccgcaccttcgaggccctcaagggggccaag
cgggccatcgtccacgtctacaactcggtcaacccgacccagcgcaactatgtgttcaac
tcagggcgcgaaggggtcaaggccatcgccgtgcagggggcgcgttgggtgcgggagtat
gcggcccgcaattcgggcaccgagtggagttttcagtactcgccggagagtttcagctgc
accgaggtggagttcgccgtcgaggtgtgtgacgcggtgatcgaccagtggcgcccggcg
gcccgcccgatgatcctgaacctgcccgccaccgtggaggtgagcacccccaacgtgttt
gccgatcaggtggagtggttctgccgccacctcaaggcgcgccccgaggtgagtatctcc
atccatacccacaacgatcggggctgcggggtggccgccgccgagttggcggtgttggcg
ggggcggatcgcatcgagggcaccctgctcggcaacggtgagcgcaccggcaacatggac
atcgtcaccatggccatgaacctctacagccaggggatcgaccccgagctcaacctggcg
gacatggatgccatcgtcgccaccgtgggagcctgcacccagattgccctgcacccgcgc
cacccctatgccggcgagctggtctacacggcgttttccggcagccaccaggacgccatc
cgcaaatccctggcggcggagaagccggatcactactgggacgtggcttacctgcccatc
gatcctgccgatctcggtcgcagctacgaggcggtgatccgcatcaacagccagtccggc
aaggggggcgttacctacctgctggagcgcgatcttggtctgcaactgccgcgttggctg
caaattgacttcagccgccgggtacaagccgaggctgaggcgagcagcagcgagataagt
ccggagcagatccgctccctgttcgagcgtcactatctcgaacccgcccacggctatcgc
atcggtcgcttccagctcggtcgcgacagccaggagagcctgcgcctcgaactgcagacc
ccgaccggctcgctgcagttgagcggtgaaggggagggggccatcacggcgctggtcaac
ggctggcagcgtcagaccgggatgcacatcgacgtgctggattactccgagcatgcctta
agcgccggcaccgagtcccgcgccgccgcctacgtgctgctgagtgtcgacgggacccgc
acctgcggggtggccatcggccgcgatgtggtcagcgcctccctgcaggcggtgatcaat
ggcgccgcccagatagaggcgctgcgccagagcgcctga

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   JCVI-CMR (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (24)   

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