KEGG T04657: 106976449

Acinonyx jubatus (cheetah): 106976449

Entry

106976449         CDS       T04657

Name

(RefSeq) serine/threonine-protein kinase PAK 1

K04409

p21-activated kinase 1 [EC:2.7.11.1]

Organism

aju Acinonyx jubatus (cheetah)

Pathway

aju04010

MAPK signaling pathway

aju04012

ErbB signaling pathway

aju04014

Ras signaling pathway

aju04024

cAMP signaling pathway

aju04062

Chemokine signaling pathway

aju04360

Axon guidance

aju04392

Hippo signaling pathway - multiple species

aju04510

Focal adhesion

aju04625

C-type lectin receptor signaling pathway

aju04650

Natural killer cell mediated cytotoxicity

aju04660

T cell receptor signaling pathway

aju04666

Fc gamma R-mediated phagocytosis

aju04810

Regulation of actin cytoskeleton

aju05132

Salmonella infection

aju05170

Human immunodeficiency virus 1 infection

aju05205

Proteoglycans in cancer

aju05211

Renal cell carcinoma

Brite

KEGG Orthology (KO) [BR:aju00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106976449
   04012 ErbB signaling pathway
    106976449
   04014 Ras signaling pathway
    106976449
   04392 Hippo signaling pathway - multiple species
    106976449
   04024 cAMP signaling pathway
    106976449
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    106976449
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    106976449
09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    106976449
   04650 Natural killer cell mediated cytotoxicity
    106976449
   04660 T cell receptor signaling pathway
    106976449
   04666 Fc gamma R-mediated phagocytosis
    106976449
   04062 Chemokine signaling pathway
    106976449
  09158 Development and regeneration
   04360 Axon guidance
    106976449
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    106976449
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    106976449
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    106976449
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    106976449
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aju01001]
    106976449
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aju04131]
    106976449
   03036 Chromosome and associated proteins [BR:aju03036]
    106976449
Enzymes [BR:aju01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     106976449
Protein kinases [BR:aju01001]
Serine/threonine kinases: STE group
  STE20 family
   106976449
Membrane trafficking [BR:aju04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    106976449
Endocytosis
  Macropinocytosis
   Kinases
    106976449
Chromosome and associated proteins [BR:aju03036]
Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     106976449

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT Kdo YrbL-PhoP_reg

Other DBs

NCBI-GeneID:

106976449

NCBI-ProteinID:

XP_014929363

UniProt:

A0A6J1XS81

Position

D1:complement(59226990..59381540)

AA seq 544 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD
DDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTIPPDALTRNTEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAFFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH

NT seq 1635 nt +upstreamnt +downstreamnt
atgtcaaataacggcctagacattcaagacaaacctccagcccctccgatgagaaacacc
agcactatgattggagctggcagcaaagatgctggaaccctaaaccacggttccaaacct
ctgcctccaaacccagaggagaagaaaaagaaggaccgattttaccgatccatcttacct
ggagataaaacaaataaaaagaaggagaaggaacggccagagatttctcttccttcagat
tttgagcacacaattcacgttggttttgatgctgtcacaggggagtttacaggaatgcca
gagcagtgggctcgcttgcttcaaacatcaaatatcactaagtcagagcagaagaaaaac
ccacaagctgttctggatgtattggaattttataactcaaagaagacctccaacagccag
aagtacatgagctttacagataaatcagctgaagattataattcttctaacactttgaat
gtgaagacggtgtctgagactcctgcagtgccaccagtttcagaagatgaagatgatgat
gatgatgctacccctcctccagtgattgctccacgcccagagcacacaaaatctgtatac
acacggtctgtgattgaaccgcttcctgttactccaactcgggatgtggctacatctccc
atttcacctactgagaataataccattccaccagatgctctgacccggaatactgagaag
cagaagaagaagcctaaaatgtctgatgaggagatcttggagaaattacggagcatagtg
agtgtgggcgatcctaagaagaaatatacacggtttgagaagattggacaaggtgcttca
ggcactgtgtacactgcaatggatgtggccacaggacaggaggtggccattaagcagatg
aaccttcagcagcagccgaagaaagagctgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtcaactacttggacagttacctcgtgggagatgagctgtgg
gttgtcatggaatacttggctggaggctctttgacagatgtggtaacagaaacttgcatg
gatgaaggccagatcgcagctgtctgccgtgagtgcctgcaggctttggagtttctgcat
tcgaaccaggtcattcacagagacatcaagagtgacaatatcctgttgggaatggatggt
tctgtcaagctaactgactttggattctgtgcccagatcaccccagagcagagcaaacgg
agcaccatggtgggaaccccatactggatggcaccagaggttgtgacacggaaagcctat
gggcccaaggttgacatctggtccctgggcatcatggccattgaaatgattgaaggggag
cccccatacctcaatgaaaatcctcttagagccttgtacctcattgccaccaatgggacc
ccagagcttcagaacccagagaagctatcagcttttttccgggactttctgaaccgctgt
cttgagatggatgtggagaagagaggttcagctaaagagctgctgcagcatcagttcctg
aagattgccaagcccctttccagcctcactccactgattgctgcagcaaaggaggcaacc
aagaacaatcactaa

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