KEGG   Amycolatopsis mediterranei U32: AMED_0482Help
Entry
AMED_0482         CDS       T01269                                 

Gene name
hemD
Definition
uroporphyrinogen-III synthase
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
amd  Amycolatopsis mediterranei U32
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
Heme biosynthesis, glutamate => protoheme/siroheme
Brite
KEGG Orthology (KO) [BR:amd00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    AMED_0482 (hemD)
Enzymes [BR:amd01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     AMED_0482 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     AMED_0482 (hemD)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
486415..487947
Genome map
AA seq 510 aa AA seqDB search
MTPARKTTGRVAFVGSGPGDAGLLTVRAQELLTKAEVVVTDPDVPQSVLAMAAEGAEVRP
AVGEATEVAKDLTTEAKAGRLVLRLVAGDPLTTPAVVAEVQAVARTSAVFDVIPGVSPAA
AVPAYAGVALGGTHTEVDVRGDVDWAALAAAPGPLVLHATSAHLAEAASALTGNGVPAST
PVAVTANGTINTQRTLDTTLEKVANDAGELVGPLIVTIGQAAGQRSKLSWWESRSLYGWK
VLVPRTKEQAGEMAERLRGHGATSHEVPTISVEPPRSPAQMERSVKGLVDGRYQWIVFTS
TNAVRAVWEKFEEFGLDARAFSGVKIACVGESTAAKVRSFGIIPELIPSGEQSSEGLLAE
FPPYDDVLDPVDRVLLPRADIATETLSAGLRERGWEIDDVTAYRTVRAAPPPAETREMIK
TGGFDAVCFTSSSTVRNLVGIAGKPHTRTLVACIGPKTAETAVEFGLRVDVQPEKADVPH
LVDALAEHAARLRAEGALPPPRKAKRARRS
NT seq 1533 nt NT seq  +upstreamnt  +downstreamnt
atgacccccgcgcgaaagaccaccgggcgcgtagcgttcgtgggctccggccccggcgac
gccggcctgctcacggtccgtgcccaggagctgctgaccaaggccgaagtggtggtgacc
gatcccgacgtgccgcagtccgtgctggccatggccgccgaaggcgccgaggtccggccc
gccgtcggcgaggccaccgaggtcgccaaggacctgaccaccgaggccaaggccggccgg
ctggtgctgcggctggtcgcgggcgacccgctgaccaccccggccgtggtggccgaggtc
caggcggtcgcgcgcacgagtgccgtgttcgacgtcatcccgggtgtctccccggccgcg
gccgtcccggcgtacgcgggcgtcgcgctgggcggcacgcacaccgaggtcgacgtccgc
ggtgacgtcgactgggcggccctggccgccgcgcccggcccgctggtgctgcacgcgacg
tcggcgcacctggccgaggccgcgtcggcgctgaccggcaacggcgtcccggcgtcgacc
ccggtcgcggtcaccgcgaacggcaccatcaacacccagcgcaccctcgacaccacgctc
gagaaggtcgccaacgacgccggcgagctcgtcgggccgctgatcgtcacgatcggccag
gccgccgggcagcgctcgaagctgtcgtggtgggagtcgcggtcgctctacggctggaag
gtcctggtgccgcgcaccaaggagcaggccggcgagatggccgagcgcctgcgcggccac
ggcgcgacgtcgcacgaggtgccgaccatctcggtcgagccgccccgcagcccggcgcag
atggagcggtcggtcaagggcctggtcgacggccgctaccagtggatcgtcttcacctcc
accaacgcggtccgcgcggtgtgggagaagttcgaggagttcggcctggacgcccgcgcg
ttctccggcgtgaagatcgcctgtgtgggtgagtcgaccgcggcgaaggtgcgctcgttc
ggcatcatcccggagctgatcccctcgggcgagcagtcgtccgaaggcctgctggccgag
ttcccgccgtacgacgacgtgctggacccggtcgaccgcgtgctgctgccgcgggccgac
atcgccaccgagacgctgtcggccggcctgcgcgaacgcggctgggagatcgacgacgtg
acggcctaccggaccgtccgggcggcgccgccgcccgccgagacccgcgagatgatcaag
accggcggcttcgacgcggtctgcttcacctcgtcctcgaccgtgcggaacctggtcggc
atcgccggcaagccgcacacccgcacgctggtcgcgtgcatcggcccgaagaccgccgag
accgcggtggagttcgggctccgggtcgacgtccagccggagaaggcggacgtcccgcac
ctggtggacgcgctggccgagcacgccgcgcggcttcgcgcggaaggtgcactgccgccg
ccgcggaaggcgaagcgggcccgccgctcctga

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