KEGG   Amycolatopsis mediterranei U32: AMED_7571
Entry
AMED_7571         CDS       T01269                                 
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase E1 component subunit alpha
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
amd  Amycolatopsis mediterranei U32
Pathway
amd00280  Valine, leucine and isoleucine degradation
amd00640  Propanoate metabolism
amd00785  Lipoic acid metabolism
amd01100  Metabolic pathways
amd01110  Biosynthesis of secondary metabolites
amd01210  2-Oxocarboxylic acid metabolism
Module
amd_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:amd00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    AMED_7571 (pdhA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    AMED_7571 (pdhA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    AMED_7571 (pdhA)
Enzymes [BR:amd01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     AMED_7571 (pdhA)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N Transketolase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: ADJ49284
UniProt: A0A0H3DHZ9
Position
complement(8362870..8363955)
AA seq 361 aa
MAVMSSETLLPSATPVRFVAEDGSRADEHGGYGEPTGDRLKEAYRLMVLGRRFDVQATAL
TKQGRLAVYPSSAGQEACQVAAALTLETRDWLFPTYRDSVALVARGLKPGEVLTLLRGDA
HCGYNPVETRVAPQCTPLATQTLHAAGLAHAMQRRGEDAVALALIGDGATSEGDFHEALN
FAAVFKAPVVFFVQNNRFAISVPFEKQSAAAALAYKGVGYGMRSEQVDGNDAVAVLAVLD
DAVKHAREGKGPVLVEAHTYRIDAHTNADDATRYRDAEEVAKWREADPLKRLETFLKSRN
LLQDTEIERFAAAAEVFAQSVRDTLNTEPELDPLSLFDHVYAEPTPQLRRQRAALEAELE
A
NT seq 1086 nt   +upstreamnt  +downstreamnt
atggctgtgatgtcttcggagaccctgctgccgtccgctaccccggtgcggttcgtcgcc
gaagacgggagccgggccgatgagcacggtgggtacggcgagcccaccggagaccggctc
aaggaggcctaccggctgatggtcctgggccgccggttcgacgtgcaggcgaccgcgctc
accaagcagggcaggctcgccgtctacccctccagcgccggccaggaggcctgccaggtc
gccgcggcgctcaccctcgaaacccgggactggctcttcccgacctaccgcgactccgtc
gccctcgtcgcccgcggcctgaagcccggcgaagtcctgacgctgcttcgcggcgacgcg
cactgcggctacaacccggtcgagacgcgcgtagcgcctcagtgcactccgctggcgacg
cagactctgcacgccgccgggctggcgcacgcgatgcagcgacgcggcgaagacgctgtc
gcgctcgcgctcattggggacggcgccaccagcgaaggcgacttccacgaagcgctcaac
ttcgcggccgtcttcaaggcgcccgtcgtgttcttcgtgcagaacaaccgcttcgccatc
tcggtgcccttcgagaagcagagcgccgcggccgcgctggcgtacaagggcgtcggctac
ggcatgcgctcggagcaggtcgacggcaacgacgccgtcgccgtcctggccgttctcgac
gacgcggtgaagcacgcgcgcgaaggcaagggaccggtcctcgtcgaggcccacacctac
cgcatcgacgcccacaccaacgccgacgacgccacccgttaccgcgacgccgaagaagtc
gcgaagtggcgcgaagcggacccgctcaagcggctcgagaccttcctcaagagccggaac
ctgctgcaggacaccgaaatcgagcggttcgcggccgccgccgaggtgttcgcccagtcc
gtccgcgacacgctcaacaccgagcccgagctcgacccgctgtcgctgttcgaccacgtc
tacgccgaacccaccccccagctgcggcggcagcgggcggccctcgaagccgaactggag
gcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (57)   

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