KEGG   Alligator mississippiensis (American alligator): 102567829
Entry
102567829         CDS       T03087                                 
Symbol
DOT1L
Name
(RefSeq) DOT1 like histone lysine methyltransferase
  KO
K11427  [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
Organism
amj  Alligator mississippiensis (American alligator)
Pathway
amj00310  Lysine degradation
amj01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:amj00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    102567829 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:amj03036]
    102567829 (DOT1L)
Enzymes [BR:amj01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.360  [histone H3]-lysine79 N-trimethyltransferase
     102567829 (DOT1L)
Chromosome and associated proteins [BR:amj03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     102567829 (DOT1L)
   HMT complexes
    Dot1-containing complex
     102567829 (DOT1L)
SSDB
Motif
Pfam: DOT1
Other DBs
NCBI-GeneID: 102567829
NCBI-ProteinID: XP_014455278
UniProt: A0A151NGS8
Position
Un
AA seq 1546 aa
MGERLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVH
ENKDSGPEEEKAGANTIKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMNTANTDRKTKKN
QTALELLHAQTVSQTSSSSPQDAYKSPHSPYYQLPPKVQRHSSNQLLVTPTPPALQKLLD
SFKIQYMQFMAYMKTPQYKANLQQLLEQEKEKNVQLLGTAQQLFTHCQAQKEEIKRLFQQ
KLDELGVKALTYNDLIQAQKEISAHNQQLKEQTKQLEKDNSELRNQSLQLLKARCEELKL
DWSTLSLENLLKEKQALKNQISEKQKHCLELQISIVELEKSQRQQELMQLKSYTPSDESL
SIQLRNKNHLSREPEVDHGRFQLELECSKFPMTHINGMSPELSMNGHATPYEIHNTLSRP
SSKQNTPQYMTSHLDQEIVPCTPNHSSRQKADKTSSLSLPDYTRFSPAKIALRRHLNQDH
AVNGKATTNEIQRADHIKENGLTYPSPNISNGMKLSPQETRPSSPAALPIAGEKVLRERT
SASNGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRVEKVRSTPSPVHQNRDSSTLE
KQIGASSHNGISNAAGNKPLALATSGFSYSSGSVAVNGTLSNSPAQLNHSVDQAALDDSG
SLFNSVGSRSSTPQHPLLMMQSRNSGQNSPAHQHSTSPRLNGASQSLVGVLQYADAQKMF
AEGTKGDLQSDAAFSDPENEAKRRIIFTISPNTGNVKQSPSNKHSPLTSSIRLDCGQAYM
QDGKKRGRRKRSSTGNLSVSSGVSPKRKSLPTVAGLFTQPSGSPLNINSMVNNINQPLEI
TAISSPENSLKNSPVPYQDNDQPPVLKKEKPLIQTNGIHYSPLTSDEEQGSEDEHNSTRI
ERKIATISLESKSPQKTVENGGSLAGRKQAQTSENMNSSKWKSTFSPISDINLTKTTDSP
LQAVSSLSQNSLFAFRPSSEDGMAIDSKITAHARKNVTMPSSGTDGLSPNTNAANGFTYN
GGLTTDIGLHSFIDGASLPHKISDVTSLNSSLSFQSQRSKDLGVSETNPFLNKRQLEGLG
SMKGEDLNRSGVKSKEMSELNIRTGGSSEKSSLQHNGKASKGRDRDVEFKNGHNLFISAA
AVSSGGLLNGKSLSTAVSSAGNPASVQTHHSFLNTLTTGSQFPLGPMALPANLNSVTNSS
VLQSLFNTMPAAASLVHVSSAATRLTNSHTMGNFSSGVTGGTVGGN
NT seq 4641 nt   +upstreamnt  +downstreamnt
atgggcgagaggctggagctccggctgaagtcgcccgtgggcgccgagccggccgtctac
ccctggccgctgcccgtctacgacaaacaccatgatgctgctcatgaaatcattgagaca
attcggtgggtctgtgaagaaatcccagatctcaagcttgctatggaaaattatgtttta
attgactatgatacaaaaagctttgaaagcatgcagaggctttgtgacaaatacaaccga
gccattgatagcattcatcagttgtggaaaggaaccacccagcccatgaaactgaacact
cgtccttccaatggactcctccgtcatatcctgcagcaagtatataaccactcggtgacc
gacccagagaaactcaacaactatgaacccttttccccagaggtgtatggagaaacttcc
tttgatttagtggcccaaatgattgatgaaattaagatgacagaggatgacttgtttgtc
gatttgggcagtggtgtgggtcaggtggtgctccaagttgctgcagccacaaactgcaaa
catcactatggtgtggagaaagctgatattccagccaaatatgctgagacgatggacaga
gagttcagaaagtggatgaaatggtatgggaaaaaacatgcagaatacacactggaaaga
ggtgacttcctctcagaagaatggagagagcgaattgcaaacacaagtgttatttttgtg
aataattttgcctttggtcctgaggtggatcaccaactgaaggagcgatttgcgaacatg
aaggaaggtggcagaatcgtgtcctcaaaaccttttgcacctctgaattttagaataaat
agtcgaaacttgagtgatattggcactataatgagagttgtggaattatcaccactgaaa
gggtctgtttcatggacagggaaaccagtttcctactacctgcatactattgatcgaacc
atacttgaaaactatttttctagtctcaaaaatccaaaactcagggaggaacaagaggca
gctagacgtcgtcagcaaagagaaaacaagagcaacacaacaactccgacaaaggtgcac
gaaaacaaggattctggtcctgaagaggaaaaagctggggcaaacaccattaagaagcca
tctccctccaaagcacgcaagaagaagctgagtaaaaaaggaaggaaaatggcaggcagg
aaacgagggcgtcctaagaagatgaacactgcaaatacggaccgcaagaccaagaagaac
caaactgcactggagcttctgcatgctcaaactgtgtcacagacatcctcatcctctcct
caggatgcatacaagtcacctcatagtccatattaccaactacctccgaaggtgcaacgg
cattcatctaaccagctgttggtgactcccaccccacctgcactacagaagctgctagac
tcttttaagatccaatacatgcagttcatggcgtacatgaaaactcctcagtacaaagca
aacctgcaacagttattggagcaggaaaaggaaaagaacgttcagttattggggacagcg
cagcagttgttcacccattgccaggcccaaaaagaggaaatcaagcgactgtttcaacaa
aagctcgatgagttgggagttaaggctctgacatataatgacctgattcaggctcagaag
gagatctctgctcacaaccagcagctgaaagaacagacgaagcagctggagaaagataac
agtgaactcaggaaccagagcttgcagctgcttaaggcacggtgtgaagaactgaaattg
gactggtcaactctttcacttgagaacttactgaaggaaaaacaggcgctgaagaatcag
atttcggagaaacaaaagcactgcttggaattgcagatcagcattgtggagcttgagaaa
agtcaaaggcagcaggagctcatgcagctgaaatcctatacgccgtccgatgagtccttg
tcaatacaactacgcaataaaaatcatctaagtcgtgaacctgaggttgatcatggcagg
ttccaacttgagcttgagtgttctaaatttcctatgacccatatcaatggcatgagtccc
gaactgtccatgaatggccatgctactccctatgaaatccataatactcttagccggccc
tcttccaagcaaaacacccctcagtatatgacctctcacctggaccaagaaatagttcca
tgtaccccaaaccacagcagtagacagaaggcggacaagacatccagcttgtccttacct
gattataccagattttcccctgctaagatagccctaaggaggcacttgaatcaggaccat
gcagtcaatggaaaagcaacaactaatgaaattcagagagctgaccacataaaagagaat
ggccttacatatccaagccctaatatttcaaatggcatgaagctgagtcctcaggaaact
cggccctcttccccagcggccttaccgattgcaggcgagaaggttttaagagagagaacc
tctgcaagtaatggagaaactatcaccagcctacctatcagtattcctctcagcacagtg
cagcccaataaactccctgttagtatccctctggccagcgtagtcctacctagccgtgtt
gagaaggtgagaagcacaccaagtccagttcatcagaatagagactcatcaacacttgaa
aagcagattggtgctagttctcataatggcataagcaatgctgctggaaacaagccactg
gctttggctacctcaggtttttcttattcttctggctccgtggcagtcaatggaactctt
tcaaacagcccagcccaacttaaccatagtgttgatcaggcagctctggacgactctggg
agtctgtttaactcggtagggtctcgcagttccactccacaacaccctttgctaatgatg
cagtcacggaactcggggcaaaactcccctgctcaccagcactcaacaagccccaggtta
aacggagcctcccagagcctggtaggggtattgcagtatgcagatgctcagaagatgttt
gctgaaggaacaaagggggatcttcagtctgatgcagcattttcagatcccgagaacgag
gccaagagaagaatcatctttacaatctctcctaatacaggaaatgtaaaacaatctcct
tccaacaagcacagtcccctgacctcgagcattcggctggactgtggtcaagcatacatg
caagatgggaagaaacgaggtcgaaggaagagatcttctactgggaatctcagcgtgagc
tctggggtgtcccccaaacgcaaatccttaccaacagtggctggactgtttactcagcct
tcagggtcaccactcaatattaactccatggtcaataacattaatcagcctttagaaata
acagccatttcctcccctgaaaactccctgaagaactctcctgttccctaccaggacaat
gaccagcccccagtgctgaaaaaggagaagcccctcattcagaccaatggcattcattac
tcgccgctgacatctgatgaagagcaggggtctgaagatgagcacaatagtaccagaatt
gagagaaaaattgcaacaatatcattggaaagcaaatctccacaaaagactgttgaaaat
ggtggcagtttagctggaagaaaacaagcgcaaaccagcgagaacatgaatagcagtaaa
tggaagtctaccttttcaccaatatctgacatcaacctgaccaaaactacagatagtccc
ttgcaggctgtttcatctctgagccagaattcactgtttgccttcaggccatcctctgag
gatggcatggccattgacagcaagatcacggcacatgcgagaaaaaatgtcaccatgccc
tcctctggaacagatggactcagccccaacacaaatgctgcaaatggattcacgtacaac
ggtggactgacgacagatattggtttacacagctttattgatggtgcttctcttcctcat
aagatttcagatgtgacttcccttaattcctctctgagttttcagtctcagcggagcaaa
gacttgggtgtctcagagacaaatccctttttgaacaagaggcagcttgaaggcctaggc
agcatgaaaggggaagacttaaatcggtcaggggtcaaaagcaaagagatgagcgaatta
aacattcgtacagggggctcttcagaaaaaagctctttgcagcataatggaaaggccagc
aaaggacgggaccgagatgtggagtttaaaaatggccacaaccttttcatttctgctgct
gctgtatcttcgggtggccttctaaatggcaaaagcctttccactgctgtttcctcagca
ggcaacccagcatctgttcagacacaccattctttcttaaacactttgaccactggatcg
cagttcccccttggccccatggccttgccagcaaacctcaactcggtgacgaactcttca
gtattgcagtctttatttaatacaatgccagctgctgccagtctggtccacgtgtcatca
gctgcaaccagactgactaattctcacactatggggaacttctcttctggggttacaggt
ggaacagttggaggtaactag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   RefSeq(pep) (8)   
DNA sequence (8)   
   RefSeq(nuc) (8)   
Protein domain (1)   
   Pfam (1)   
All databases (38)   

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