KEGG   Ailuropoda melanoleuca (giant panda): 100464991Help
Entry
100464991         CDS       T01329                                 

Gene name
PDGFRA
Definition
platelet-derived growth factor receptor, alpha polypeptide
Orthology
K04363  
platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Central carbon metabolism in cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100464991 (PDGFRA)
   04015 Rap1 signaling pathway
    100464991 (PDGFRA)
   04010 MAPK signaling pathway
    100464991 (PDGFRA)
   04020 Calcium signaling pathway
    100464991 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    100464991 (PDGFRA)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100464991 (PDGFRA)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    100464991 (PDGFRA)
  Cell motility
   04810 Regulation of actin cytoskeleton
    100464991 (PDGFRA)
  Cellular commiunity
   04510 Focal adhesion
    100464991 (PDGFRA)
   04540 Gap junction
    100464991 (PDGFRA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100464991 (PDGFRA)
   05230 Central carbon metabolism in cancer
    100464991 (PDGFRA)
   05231 Choline metabolism in cancer
    100464991 (PDGFRA)
   05206 MicroRNAs in cancer
    100464991 (PDGFRA)
   05214 Glioma
    100464991 (PDGFRA)
   05218 Melanoma
    100464991 (PDGFRA)
   05215 Prostate cancer
    100464991 (PDGFRA)
  Infectious diseases
   05166 HTLV-I infection
    100464991 (PDGFRA)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100464991 (PDGFRA)
Protein kinases [BR:aml01001]
 Tyrosine protein kinases
  PDGFR family [OT]
   100464991 (PDGFRA)
Enzyme-linked receptors [BR:aml01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   100464991 (PDGFRA)
Cytokine receptors [BR:aml04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   100464991 (PDGFRA)
Cellular antigens [BR:aml04090]
 Proteins
  100464991 (PDGFRA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
Un
AA seq 1089 aa AA seqDB search
MRTSLLGFLILGCLLTGPSRIFCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVAVLEVVNASAAHTGLYTCYYNHTQTEETDVEGRRIYIY
VPDPDVAFVPLGMTDYLVIVENDDSAIIPCRTTDPKTPVTLRSNDRVVHASYDSRQGFNG
TFSVGPYICEATVRGKKFQTIPFNIYSLKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEVK
EMKKVTISVYEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWVILASNISNIITEVHPRD
RNTVEGRVTFTRVEETIAVRCLAKNLLGAQSRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRSY
VILSFENNGDYMDMKQADATQYVPMLERKEAAKYSDVQRSLYDRPASSKKKSVLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq 3270 nt NT seq  +upstreamnt  +downstreamnt
atgaggacttcccttctgggcttcctgatcttaggctgtctcctcacagggcccagccga
atcttctgccagctttcattaccctccatcctgccaaacgaaaatgaaaaggtcgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagaaacgaggagaacaacagtggcctt
tttgtggccgtgctggaagtggtcaacgcgtcggcggcacacacgggcttgtacacttgc
tattacaaccacacgcagacggaggagaccgacgtcgagggccggcgtatctacatctat
gtgccagacccggatgtagcctttgtgcctctgggaatgacagattatttagtcatcgtg
gagaatgatgattctgccatcataccatgtcgcacgactgatcccaagactccggtcacc
ttgcgcagcaatgacagggtggtgcacgcctcctatgacagcagacagggcttcaatggg
accttcagcgttgggccctatatctgtgaagccaccgtcaggggaaagaagttccagacc
atcccatttaatatttattctttaaaagcaacgtcagaacttgatctagaaatggaagct
cttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggtcgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcaccatg
ctggaggaaatcaaggtcccgtccatcaaattggtgtatactctgagggtccctgaggcc
acggtgaaagatagtggagattatgagtgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttctgtctatgagaaagggttcattgaaatcaaacccaac
ttcagcccattggaagctgtcgacctgcatgaagtcaaacatttcgtggtggatgtgcag
gcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acggagatcaccacggacatagaaaagattcaggaaataaggtatcggagcaaattaaag
ctgatccgtgctaaggaggaagacagtggccattacacgattgtcgttcaaaatgaagat
gacgtgaagagctacactttcgaactcttaacgcaagttccctcatctattctggacttg
gtggacgaccaccacggctccacggggggacagaccgtgagatgcaccgctgaagggaca
cctcttcctgatatcgagtggatgatttgcaaggatattaagaagtgtaataatgaaact
tcatgggtgattttggccagcaatatctcaaacatcatcacggaggtccacccccgagac
aggaacactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgttcga
tgtctggccaagaatctccttggggcccagagccgcgagctcaagctggtggcccccacg
ctgcgctctgagctcactgtggccgctgccgtcctcgtgctgctggtgattgtgatcatc
tcccttatcgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctggagg
gtcattgaatccatcagcccggatggacatgaatatatttatgtggacccaatgcagctg
ccttatgactcgagatgggagtttccaagagatggactagtgcttggtcgtatcctggga
tctggcgcgtttgggaaagtggttgaaggaactgcctatggattaagccgctcccagcct
gtcatgaaggtagcagtgaagatgctgaaacccacagccagatccagtgagaaacaggct
cttatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaacttg
ctgggagcctgtaccaagtcaggccctatttacatcatcactgagtactgcttctatggg
gatttggtcaactatttgcataagaatcgggatagcttcctgagccgccacccagagaag
ccaaagaaagagctggacatttttggattgaaccctgccgacgacagcacacggagttac
gtcattttatcttttgaaaacaatggtgactacatggacatgaagcaagctgacgccacc
cagtacgtccccatgctggaaaggaaagaggctgccaagtactcggacgtccagaggtcg
ctgtatgatcgcccggcctcgtctaagaagaagtctgtgttagactcagaagtcaaaaac
ctcctttcggatgataactcagaaggccttactttgttggatttgttgagctttacctat
caagttgcgcgaggaatggaatttttggcttcgaaaaattgtgtccaccgggacctggct
gctcgaaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgacttcggcctggcc
agagatatcatgcacgattcgaactacgtgtcaaaaggcagtacctttctccccgtgaag
tggatggcccctgagagcatcttcgacaacctctacaccacactgagtgacgtctggtct
tacggcattctgctctgggagatcttttccctcggcggcacaccctaccccggcatgatg
gtggattctactttctacaataagattaagagtgggtaccggatggccaagcctgaccac
gccaccagtgaagtctacgagatcatggtgaaatgctggcacagtgagccggagaagaga
ccctccttctaccacctgagtgagattgtggagaatctgctgcccggacagtataagaag
agttacgaaaagattcacctggacttcctgaagagcgaccaccccgccgtggcgcgcatg
cgcgtggactcagacaacgcctacattggcgttacctacaaaaacgaggaagacaagctg
aaggactgggagggcagcctggacgagcagaggctgagtgcggacagcggctacatcatc
cccctgcccgacatcgaccctgtccctgaggaggaggacctgggcaagaggaacagacac
agctcgcagacctccgaagagagcgctatcgagacaggttcgagtagctccaccttcatc
aagagagaggacgagaccatcgaggacatcgacatgatggatgacattggcatagactcc
tcagacctggtagaggacagtttcctgtga

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