KEGG   Ailuropoda melanoleuca (giant panda): 100464991Help
Entry
100464991         CDS       T01329                                 

Gene name
PDGFRA
Definition
(RefSeq) platelet-derived growth factor receptor, alpha polypeptide
  KO
K04363  
platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Central carbon metabolism in cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100464991 (PDGFRA)
   04015 Rap1 signaling pathway
    100464991 (PDGFRA)
   04010 MAPK signaling pathway
    100464991 (PDGFRA)
   04020 Calcium signaling pathway
    100464991 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    100464991 (PDGFRA)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100464991 (PDGFRA)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    100464991 (PDGFRA)
  Cell motility
   04810 Regulation of actin cytoskeleton
    100464991 (PDGFRA)
  Cellular commiunity
   04510 Focal adhesion
    100464991 (PDGFRA)
   04540 Gap junction
    100464991 (PDGFRA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100464991 (PDGFRA)
   05230 Central carbon metabolism in cancer
    100464991 (PDGFRA)
   05231 Choline metabolism in cancer
    100464991 (PDGFRA)
   05206 MicroRNAs in cancer
    100464991 (PDGFRA)
   05214 Glioma
    100464991 (PDGFRA)
   05218 Melanoma
    100464991 (PDGFRA)
   05215 Prostate cancer
    100464991 (PDGFRA)
  Infectious diseases
   05166 HTLV-I infection
    100464991 (PDGFRA)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100464991 (PDGFRA)
Protein kinases [BR:aml01001]
 Tyrosine protein kinases
  PDGFR family [OT]
   100464991 (PDGFRA)
Enzyme-linked receptors [BR:aml01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   100464991 (PDGFRA)
Cytokine receptors [BR:aml04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   100464991 (PDGFRA)
Cellular antigens [BR:aml04090]
 Proteins
  100464991 (PDGFRA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
Un
AA seq 1090 aa AA seqDB search
MMRTSLLGFLILGCLLTGPSRIFCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQY
PMSEEENPNVEIRNEENNSGLFVAVLEVVNASAAHTGLYTCYYNHTQTEETDVEGRRIYI
YVPDPDVAFVPLGMTDYLVIVENDDSAIIPCRTTDPKTPVTLRSNDRVVHASYDSRQGFN
GTFSVGPYICEATVRGKKFQTIPFNIYSLKATSELDLEMEALKTVYKSGETIVVTCAVFN
NEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEV
KEMKKVTISVYEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIEN
LTEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILD
LVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWVILASNISNIITEVHPR
DRNTVEGRVTFTRVEETIAVRCLAKNLLGAQSRELKLVAPTLRSELTVAAAVLVLLVIVI
ISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRIL
GSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVN
LLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRS
YVILSFENNGDYMDMKQADATQYVPMLERKEAAKYSDVQRSLYDRPASSKKKSVLDSEVK
NLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGL
ARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGM
MVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYK
KSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYI
IPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGID
SSDLVEDSFL
NT seq 3273 nt NT seq  +upstreamnt  +downstreamnt
atgatgaggacttcccttctgggcttcctgatcttaggctgtctcctcacagggcccagc
cgaatcttctgccagctttcattaccctccatcctgccaaacgaaaatgaaaaggtcgtg
cagctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtac
cccatgtctgaagaagagaaccccaatgtggaaatcagaaacgaggagaacaacagtggc
ctttttgtggccgtgctggaagtggtcaacgcgtcggcggcacacacgggcttgtacact
tgctattacaaccacacgcagacggaggagaccgacgtcgagggccggcgtatctacatc
tatgtgccagacccggatgtagcctttgtgcctctgggaatgacagattatttagtcatc
gtggagaatgatgattctgccatcataccatgtcgcacgactgatcccaagactccggtc
accttgcgcagcaatgacagggtggtgcacgcctcctatgacagcagacagggcttcaat
gggaccttcagcgttgggccctatatctgtgaagccaccgtcaggggaaagaagttccag
accatcccatttaatatttattctttaaaagcaacgtcagaacttgatctagaaatggaa
gctcttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaac
aacgaggtggtcgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcacc
atgctggaggaaatcaaggtcccgtccatcaaattggtgtatactctgagggtccctgag
gccacggtgaaagatagtggagattatgagtgtgctgcccgccaggccaccaaggaggtc
aaagagatgaagaaagtcaccatttctgtctatgagaaagggttcattgaaatcaaaccc
aacttcagcccattggaagctgtcgacctgcatgaagtcaaacatttcgtggtggatgtg
caggcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaat
ctcacggagatcaccacggacatagaaaagattcaggaaataaggtatcggagcaaatta
aagctgatccgtgctaaggaggaagacagtggccattacacgattgtcgttcaaaatgaa
gatgacgtgaagagctacactttcgaactcttaacgcaagttccctcatctattctggac
ttggtggacgaccaccacggctccacggggggacagaccgtgagatgcaccgctgaaggg
acacctcttcctgatatcgagtggatgatttgcaaggatattaagaagtgtaataatgaa
acttcatgggtgattttggccagcaatatctcaaacatcatcacggaggtccacccccga
gacaggaacactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgtt
cgatgtctggccaagaatctccttggggcccagagccgcgagctcaagctggtggccccc
acgctgcgctctgagctcactgtggccgctgccgtcctcgtgctgctggtgattgtgatc
atctcccttatcgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctgg
agggtcattgaatccatcagcccggatggacatgaatatatttatgtggacccaatgcag
ctgccttatgactcgagatgggagtttccaagagatggactagtgcttggtcgtatcctg
ggatctggcgcgtttgggaaagtggttgaaggaactgcctatggattaagccgctcccag
cctgtcatgaaggtagcagtgaagatgctgaaacccacagccagatccagtgagaaacag
gctcttatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaac
ttgctgggagcctgtaccaagtcaggccctatttacatcatcactgagtactgcttctat
ggggatttggtcaactatttgcataagaatcgggatagcttcctgagccgccacccagag
aagccaaagaaagagctggacatttttggattgaaccctgccgacgacagcacacggagt
tacgtcattttatcttttgaaaacaatggtgactacatggacatgaagcaagctgacgcc
acccagtacgtccccatgctggaaaggaaagaggctgccaagtactcggacgtccagagg
tcgctgtatgatcgcccggcctcgtctaagaagaagtctgtgttagactcagaagtcaaa
aacctcctttcggatgataactcagaaggccttactttgttggatttgttgagctttacc
tatcaagttgcgcgaggaatggaatttttggcttcgaaaaattgtgtccaccgggacctg
gctgctcgaaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgacttcggcctg
gccagagatatcatgcacgattcgaactacgtgtcaaaaggcagtacctttctccccgtg
aagtggatggcccctgagagcatcttcgacaacctctacaccacactgagtgacgtctgg
tcttacggcattctgctctgggagatcttttccctcggcggcacaccctaccccggcatg
atggtggattctactttctacaataagattaagagtgggtaccggatggccaagcctgac
cacgccaccagtgaagtctacgagatcatggtgaaatgctggcacagtgagccggagaag
agaccctccttctaccacctgagtgagattgtggagaatctgctgcccggacagtataag
aagagttacgaaaagattcacctggacttcctgaagagcgaccaccccgccgtggcgcgc
atgcgcgtggactcagacaacgcctacattggcgttacctacaaaaacgaggaagacaag
ctgaaggactgggagggcagcctggacgagcagaggctgagtgcggacagcggctacatc
atccccctgcccgacatcgaccctgtccctgaggaggaggacctgggcaagaggaacaga
cacagctcgcagacctccgaagagagcgctatcgagacaggttcgagtagctccaccttc
atcaagagagaggacgagaccatcgaggacatcgacatgatggatgacattggcatagac
tcctcagacctggtagaggacagtttcctgtga

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