KEGG   Ailuropoda melanoleuca (giant panda): 100465232Help
Entry
100465232         CDS       T01329                                 

Gene name
PLCB3
Definition
phospholipase C, beta 3 (phosphatidylinositol-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:aml00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:aml04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:aml04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:aml04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:aml04070]
Cellular Processes; Cell communication; Gap junction [PATH:aml04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:aml04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:aml04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:aml04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:aml04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:aml04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:aml04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:aml04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:aml04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:aml04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:aml04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:aml04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:aml04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:aml04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:aml04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:aml04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:aml04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:aml04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:aml04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:aml04720]
Organismal Systems; Nervous system; Long-term depression [PATH:aml04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:aml04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:aml04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:aml04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:aml05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:aml05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:aml05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:aml05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:aml05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1208 aa AA seqDB search
MGFEADEASSRNLVTLRVDSNGFFLYWTGPNMEVDTLDISSIRDTRTGRYARLPKDPKIR
EVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNFMAVQDDTAKVWTEELFKLAMNILAQNA
SRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFSADKKRVETALESCGLNFNRSESIRPDE
FSLEIFERFLNKLCLRPDIDKILLEIGAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPL
RPSQARLLIEKYEPNQQFLERDQMSMEGFSRYLGGEENGILPLEALDLSTDMTQPLSAYF
INSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEV
PLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIDPLDKYPL
APGVSLPSPQDLMGRILVKNKKRHRPSTGVPNSSVRKRPLEQSNSALSESSAATEPSSPQ
LGSPSSDSCPGLSNGEEVGPEKPSLEPQKSLGEDGLPRGPDALGSADREDEEEEEEEEEQ
TDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVKFKSFEAARKRNKCFEMSSFVETKAME
QLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNA
GVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRKVGIYV
EVDIFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVG
HRILPVSAIRSGYHYICLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVS
LMDQRAKQLAALIGESEAQASPETCQETQSQQLGSQLTPNPTPSPLDTSPRRPPGPATSP
TSPSLSSPGQRDDLIASLLSEVAPTPLDELRGHKALVKLRSRQERELRELHKKHQRKAVA
LTRRLLDGLAQARAEGRCRQRPGVLGSSYRSGENEKEEEEEVRRYQEFQKRQVQSLLELR
EAQADTEAERRLEHLRQAQQRLREIVLDFHTTQFKRLKEMNEREKKELQKILDRKRHNSI
SEAKTREKHKKEAELTEINRRHITESVNSIRRLEEAQKQRHERLVAGQQQVLQQLAEEEP
KLLAQLAQECQEQRARLPQEIRRSLLGDTPEGLGDGHLVACASNGHAPGSGGHLSGADSE
SQEENTKL
NT seq 3627 nt NT seq  +upstreamnt  +downstreamnt
atggggtttgaggccgatgaggcctccagtcggaatctggtaaccctgcgtgtggactct
aatggcttctttctgtactggaccggacccaacatggaggtggacacactggacatcagt
tccatcagggacacgcggacggggcgttacgcccgcctgcccaaggaccccaagatccgg
gaggtgctgggctttgggggccctgacgctcggctggaggagaagttgatgacggtggtg
gccgggccagacccggtgaatacgacattcttgaacttcatggccgtgcaggatgacaca
gccaaggtctggactgaggagctgttcaagctggctatgaacatcctggctcagaatgcc
tcccggaacaccttcctgcgaaaagcgtacacaaagctgaaactgcaagtgaaccaggat
ggacggatcccggtgaagaatatcctgaagatgttttcagcagataaaaagcgagtagag
actgcactggaatcctgtggcctcaatttcaaccggagtgagtccatccggccagacgaa
ttttccttggaaatcttcgagcggttcctgaataagttgtgtctgcggccagacattgac
aagatcctgctggagataggcgccaagggcaagccgtacctgacgctggagcagctcatg
gacttcatcaaccagaagcaacgggacccgaggctcaacgaagtgctgtacccacccctg
cggccctcgcaggcccggctgctcattgagaagtatgagcccaaccagcagtttctggag
cgagaccagatgtccatggagggcttcagccgctacctgggaggtgaggagaatggcatc
ttgcctctggaggccctggatctgagcacagacatgacacagccgctgagcgcctacttc
atcaactcctcacacaacacctatctcacagcggggcagctggccgggacctcgtcggtg
gagatgtaccgccaggcgctgctgtggggctgccgctgcgtggagctggatgtgtggaaa
gggcggccgcctgaggaggagcccttcatcacccacggcttcaccatgaccaccgaggtg
ccgctgcgagatgtgctcgaggccatcgcggaaaccgccttcaagacctcgccctacccc
gtcatcctctccttcgagaaccacgtggactcggcaaagcagcaggccaagatggccgag
tactgccgttccatctttggggacgcgctgctcatcgacccgctggacaagtacccgctg
gcgccaggcgtctccctgcccagcccccaggacctgatgggccgcatcctggtgaagaac
aaaaagcgacaccggcccagcactggtgtccccaacagctctgtgcgtaagcggccgctg
gagcagagcaactcggctctgagcgagagctctgccgccaccgagccctcctcacctcag
ctcgggtcccccagttctgacagctgcccaggcctgagcaatggggaagaggtgggcccg
gagaagcccagcctggagcctcaaaagtctctgggtgaggacgggctaccgaggggccct
gatgctcttgggtctgctgaccgtgaggacgaggaggaagaggaggaagaggaggaacag
acagatcccaaaaagccgaccacagatgagggcactgccagcagtgaggtcaatgccacc
gaggaaatgtcaacactcgtcaactacatcgagcctgtcaagttcaagtcctttgaggct
gctcgaaaaaggaacaaatgcttcgagatgtcatcctttgtggaaaccaaggccatggag
cagctgaccaagagccccatggagtttgtggaatacaataagcagcagctcagccggatc
taccccaagggcacccgcgtggactcatccaactacatgccccagctcttctggaacgtc
ggctgccagcttgttgcgctcaacttccagaccctggacgtggcgatgcagcttaacgca
ggtgtgttcgagtacaacgggcgcagcggctacctgctcaagcccgagttcatgcggcgg
ccagacaagtcctttgatcccttcaccgaggtcatcgtggacggcatcgtggccaatgcc
ttgcgggtcaaggtgatctcggggcagttcctgtccgacaggaaggtgggcatctacgtg
gaggtggacatatttggcctccccgtggacacacggcgcaagtaccgcactcggacctct
caggggaactccttcaatcccgtgtgggacgaggagccctttgacttccccaaggtggtg
ctgcccacactggcttcgctgcgcatcgcggcctttgaggagggaggcaagtttgtgggg
catcggattctgcctgtctctgccatccgctcaggataccactacatctgtctgcggaac
gaggccaaccagccgctctgcctgccggccctgctcatctacaccgaagcctctgactac
atccctgacgaccaccaggactacgccgaggccttgatcaaccccatcaagcacgtcagc
ctgatggaccagagagccaagcagttggccgccctcattggggagagcgaggctcaggcc
agcccagagacctgccaggagactcagtctcagcagctggggtcccagctgaccccaaac
cccacacccagcccgctggacacctccccgcgccggcccccaggccctgccacgtcccct
accagcccctcgctcagcagtccagggcagcgggacgacctcatcgccagcctcctgtca
gaggtggccccgaccccgctggacgagctccgaggccacaaggccctggtgaagctccgg
agccggcaggagcgagagctgcgggagctgcacaagaagcaccagcggaaggccgtcgcc
ctcacgcgccggctcctcgacggcctggctcaggcgcgggcggagggcaggtgccgccag
cggccgggggtcctgggctcttcctacagaagcggggaaaacgagaaggaggaggaggaa
gaggtgaggcggtatcaagagttccagaagagacaggtgcagagtctgctggagctgagg
gaggcccaggcggatacagaggctgagcggaggctggagcacctgagacaggctcagcag
cggctcagggagattgtcctggattttcacacaactcagttcaagaggctgaaggagatg
aacgagagggagaagaaggaactgcagaagattctggacaggaagcgccacaacagtatc
tcagaggccaagacaagggagaaacataagaaggaggcggaactgacagagattaaccgg
cggcatatcaccgagtcggtcaactccatccgtcggctggaggaggcccagaagcagcgg
catgagcgccttgtggccgggcagcaacaggtcctacagcagctggcagaagaggagccc
aagctgctggcccagctggcccaggagtgtcaggagcagcgggcaaggctgccccaggag
atccgccggagcctgctgggcgacacgccggaggggctgggggacgggcatctggtggcc
tgtgccagcaacggtcatgcacccgggagcggcgggcacctgtctggtgctgactcggag
agccaagaggagaatacgaagctctga

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