KEGG   Ailuropoda melanoleuca (giant panda): 100468252Help
Entry
100468252         CDS       T01329                                 

Gene name
PRKACA
Definition
(RefSeq) protein kinase, cAMP-dependent, catalytic, alpha
  KO
K04345  
protein kinase A [EC:2.7.11.11]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Regulation of lipolysis in adipocytes
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Module
cAMP signaling
Brite
KEGG Orthology (KO) [BR:aml00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100468252 (PRKACA)
   04010 MAPK signaling pathway
    100468252 (PRKACA)
   04310 Wnt signaling pathway
    100468252 (PRKACA)
   04340 Hedgehog signaling pathway
    100468252 (PRKACA)
   04020 Calcium signaling pathway
    100468252 (PRKACA)
   04024 cAMP signaling pathway
    100468252 (PRKACA)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    100468252 (PRKACA)
   04210 Apoptosis
    100468252 (PRKACA)
  Cellular commiunity
   04540 Gap junction
    100468252 (PRKACA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100468252 (PRKACA)
   04062 Chemokine signaling pathway
    100468252 (PRKACA)
  Endocrine system
   04911 Insulin secretion
    100468252 (PRKACA)
   04910 Insulin signaling pathway
    100468252 (PRKACA)
   04922 Glucagon signaling pathway
    100468252 (PRKACA)
   04923 Regulation of lipolysis in adipocyte
    100468252 (PRKACA)
   04912 GnRH signaling pathway
    100468252 (PRKACA)
   04913 Ovarian Steroidogenesis
    100468252 (PRKACA)
   04915 Estrogen signaling pathway
    100468252 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    100468252 (PRKACA)
   04921 Oxytocin signaling pathway
    100468252 (PRKACA)
   04918 Thyroid hormone synthesis
    100468252 (PRKACA)
   04919 Thyroid hormone signaling pathway
    100468252 (PRKACA)
   04916 Melanogenesis
    100468252 (PRKACA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100468252 (PRKACA)
   04270 Vascular smooth muscle contraction
    100468252 (PRKACA)
  Digestive system
   04970 Salivary secretion
    100468252 (PRKACA)
   04971 Gastric acid secretion
    100468252 (PRKACA)
   04976 Bile secretion
    100468252 (PRKACA)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    100468252 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100468252 (PRKACA)
  Nervous system
   04724 Glutamatergic synapse
    100468252 (PRKACA)
   04727 GABAergic synapse
    100468252 (PRKACA)
   04725 Cholinergic synapse
    100468252 (PRKACA)
   04728 Dopaminergic synapse
    100468252 (PRKACA)
   04726 Serotonergic synapse
    100468252 (PRKACA)
   04720 Long-term potentiation
    100468252 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    100468252 (PRKACA)
  Sensory system
   04740 Olfactory transduction
    100468252 (PRKACA)
   04742 Taste transduction
    100468252 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    100468252 (PRKACA)
  Environmental adaptation
   04713 Circadian entrainment
    100468252 (PRKACA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100468252 (PRKACA)
   05205 Proteoglycans in cancer
    100468252 (PRKACA)
   05203 Viral carcinogenesis
    100468252 (PRKACA)
  Neurodegenerative diseases
   05012 Parkinson's disease
    100468252 (PRKACA)
   05020 Prion diseases
    100468252 (PRKACA)
  Substance dependence
   05030 Cocaine addiction
    100468252 (PRKACA)
   05031 Amphetamine addiction
    100468252 (PRKACA)
   05032 Morphine addiction
    100468252 (PRKACA)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    100468252 (PRKACA)
  Infectious diseases
   05166 HTLV-I infection
    100468252 (PRKACA)
   05169 Epstein-Barr virus infection
    100468252 (PRKACA)
   05146 Amoebiasis
    100468252 (PRKACA)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100468252 (PRKACA)
Protein kinases [BR:aml01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   100468252 (PRKACA)
Messenger RNA biogenesis [BR:aml03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     100468252 (PRKACA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
Un
AA seq 343 aa AA seqDB search
MASNPNHVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGN
HFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGE
MFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGF
AKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY
EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQ
RKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
NT seq 1032 nt NT seq  +upstreamnt  +downstreamnt
atggcttccaaccccaaccatgtgaaagagttcttagccaaagccaaagaagattttctt
aaaaaatgggaaaatcctgctcagaatacagcccatttggatcagtttgaacgaatcaag
accctcggcacgggctcctttgggcgggtgatgctggtaaagcacaaggagaccgggaac
cactttgccatgaagatcctcgacaaacagaaggtggtgaaactgaaacagatcgagcat
accctgaacgaaaagcgcatcctgcaagcggtcaactttccgttcctcgtcaaactcgag
ttctccttcaaggacaactcgaatttatacatggtcatggagtacgtgcctggcggggag
atgttctcgcacctgcggcggattggaaggttcagtgaaccacatgcccgcttctatgcg
gcccagatcgtcctgaccttcgagtacctgcactcacttgacctcatctaccgggacctg
aagccggagaacctcctcattgaccagcagggctacattcaggtgacagacttcggtttt
gccaagcgtgtaaaaggccgcacctggaccttatgcgggacccctgagtacctggccccg
gagatcattctgagcaaaggctacaacaaggctgtggactggtgggccctgggagttctc
atctacgagatggctgctggctacccgcccttcttcgctgaccagcccatccagatctat
gagaagattgtctctgggaaggtgcggttcccatcccacttcagctccgacctgaaggat
ctgctgcggaacctgctgcaggtggacctcaccaaacgcttcgggaacctcaagaatggg
gtcaatgatatcaagaaccacaagtggtttgccacaactgactggatcgccatctaccag
aggaaggtggaagctcccttcataccaaagttcaaaggccctggggacacgagtaatttt
gacgactatgaggaggaagagatccgagtctccatcaatgagaagtgtggcaaggagttt
actgagttttag

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