KEGG   Ailuropoda melanoleuca (giant panda): 100470322Help
Entry
100470322         CDS       T01329                                 

Gene name
PIK3CG
Definition
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
  KO
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100470322 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100470322 (PIK3CG)
   04015 Rap1 signaling pathway
    100470322 (PIK3CG)
   04012 ErbB signaling pathway
    100470322 (PIK3CG)
   04370 VEGF signaling pathway
    100470322 (PIK3CG)
   04630 Jak-STAT signaling pathway
    100470322 (PIK3CG)
   04668 TNF signaling pathway
    100470322 (PIK3CG)
   04066 HIF-1 signaling pathway
    100470322 (PIK3CG)
   04068 FoxO signaling pathway
    100470322 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    100470322 (PIK3CG)
   04071 Sphingolipid signaling pathway
    100470322 (PIK3CG)
   04024 cAMP signaling pathway
    100470322 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    100470322 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    100470322 (PIK3CG)
   04152 AMPK signaling pathway
    100470322 (PIK3CG)
   04150 mTOR signaling pathway
    100470322 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100470322 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    100470322 (PIK3CG)
  Cellular commiunity
   04510 Focal adhesion
    100470322 (PIK3CG)
   04550 Signaling pathways regulating pluripotency of stem cells
    100470322 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100470322 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    100470322 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    100470322 (PIK3CG)
   04660 T cell receptor signaling pathway
    100470322 (PIK3CG)
   04662 B cell receptor signaling pathway
    100470322 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    100470322 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    100470322 (PIK3CG)
   04670 Leukocyte transendothelial migration
    100470322 (PIK3CG)
   04062 Chemokine signaling pathway
    100470322 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    100470322 (PIK3CG)
   04923 Regulation of lipolysis in adipocyte
    100470322 (PIK3CG)
   04915 Estrogen signaling pathway
    100470322 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    100470322 (PIK3CG)
   04917 Prolactin signaling pathway
    100470322 (PIK3CG)
   04921 Oxytocin signaling pathway
    100470322 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    100470322 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100470322 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100470322 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100470322 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    100470322 (PIK3CG)
   04722 Neurotrophin signaling pathway
    100470322 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100470322 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    100470322 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100470322 (PIK3CG)
   05230 Central carbon metabolism in cancer
    100470322 (PIK3CG)
   05231 Choline metabolism in cancer
    100470322 (PIK3CG)
   05205 Proteoglycans in cancer
    100470322 (PIK3CG)
   05203 Viral carcinogenesis
    100470322 (PIK3CG)
   05210 Colorectal cancer
    100470322 (PIK3CG)
   05212 Pancreatic cancer
    100470322 (PIK3CG)
   05214 Glioma
    100470322 (PIK3CG)
   05221 Acute myeloid leukemia
    100470322 (PIK3CG)
   05220 Chronic myeloid leukemia
    100470322 (PIK3CG)
   05218 Melanoma
    100470322 (PIK3CG)
   05211 Renal cell carcinoma
    100470322 (PIK3CG)
   05215 Prostate cancer
    100470322 (PIK3CG)
   05213 Endometrial cancer
    100470322 (PIK3CG)
   05222 Small cell lung cancer
    100470322 (PIK3CG)
   05223 Non-small cell lung cancer
    100470322 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100470322 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100470322 (PIK3CG)
   04931 Insulin resistance
    100470322 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100470322 (PIK3CG)
   05166 HTLV-I infection
    100470322 (PIK3CG)
   05162 Measles
    100470322 (PIK3CG)
   05164 Influenza A
    100470322 (PIK3CG)
   05161 Hepatitis B
    100470322 (PIK3CG)
   05160 Hepatitis C
    100470322 (PIK3CG)
   05169 Epstein-Barr virus infection
    100470322 (PIK3CG)
   05146 Amoebiasis
    100470322 (PIK3CG)
   05145 Toxoplasmosis
    100470322 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    100470322 (PIK3CG)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100470322 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
Un
AA seq 1102 aa AA seqDB search
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKISNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPSGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt
atggagctggagaactatgagcagcctgtggttctgagagaggacaaccgccgccggcgc
cggaggatgaagccgcgcagctccgcggccagcctgtcctccatggagctcatccccatc
gagttcgtgctgcccaccagccagcgccacagcaagacccccgagacggcgctgctgcac
gtggccggccacggcaatgtggagcagatgaaggcccaggtgtggctgcgcgcactggag
acgagcgtggcggccgacttctaccaccggctcggcccggaccacttcctcctgctctac
cagaagaagggccagtggtacgagatctacgacaagcaccaggtggtgcagaccctggac
tgcctgcgctactggcaggtgctgcaccggagcccgggccagatccacgtggtgcagagg
cgcgcgccgtccgacgagacgctggccttccagcgccagctcaccgccctgatcggctac
gacgtcaccgacgtcagcaacgtgcacgacaacgagctcgagttcacgcgccgccgcctg
gtcactccgcgcatggtcgaggtggccggccgcgaccccaagctctacgccatgcacccg
tgggtgacctccaagcctctcccggagtacctgctgaagaagattagcaacaactgcatc
ttcatcgtcattcaccgcagcaccaccagccagaccatcaaggtctcggccgacgacacc
ccgggcaccatcctccagagcttcttcaccaagatggccaagaagaagtctctgctggat
atccccgagagccaaaacgaacaggattttgtgctgcgcgtctgcggccgggacgagtac
ctggtaggcgaaacgcccatcaagaacttccagtgggtgaggcattgcctcaagaacgga
gaagagattcacctggtgctggactcgcctccagacccggccctggacgaggtgaggaaa
gaagagtggccgctggtagatgactgcacgggagtcaccggctaccacgagcagctgact
atccacgggaaggaccatgagagtgtgttcaccgtgtccctgtgggactgcgaccggaag
ttcagggtcaaaatcagaggcattgatatccctgtgctgccccggaacgctgacctcaca
gtttttgtggaggccaacatccagcacgggcagcaggtcctgtgccaaaggagaacgagc
cccaaacccttcacggaggaggtgctctggaacgtgtggcttgagttcagtatccaaatc
aaagacttacccaggggggctctgctgaacctccagatctactgcagcaaagctccggcg
ccgtccggcaagggctccgcggacactccgggctcggagggcaaaggcaaagcgcagctg
ctctattatgtgaacctgctgctgatcgaccaccggttcctgctgcgccacggggagtac
gtgctccacatgtggcagatctcgggaaagggagaagaccaggggagcttcagtgctgac
aagctcacgtcggcgaccaacccagacaaggagaactccatgtcaatctccattcttctg
gacaattactgtcacccaatcgccttgcccaagcatcggccaacccctgaccccgaaggg
gaccgggtgcgagcggagatgcccaatcagcttcggaagcaactggaggcgatcatagcc
acggatccacttaaccccctcacggcagaggacaaagaactgctctggcattttagatac
gaaagtcttaagcatccaaaggcctatcccaagctgtttagctccgtaaaatggggacag
caagaaattgtagccaaaacataccaactgttagccagacgggaggtctgggaccaaagt
gctttggatgttgggttaacgatgcaacttctggactgcaacttttcagatgaaaatgta
agagccatcgcagttcagaagctggagagcttggaggacgatgatgtcctgcattacctg
ctacagctggtccaggccgtgaaattcgagccatatcatgacagcgccctggcccgattt
ctgctgaaacgaggcttaaggaacaaaagaattggccatttcttgttttggttcttgaga
agcgagatagcccagtccaggcactatcagcagaggtttgccgtgctcctggaggcctat
ctgaggggctgcggcacggccatgctgcacgacttctcccaacaagttcacgtgatcgag
atgctgcagaaggtcaccattgatattaaatcactctctgcggaaaagtatgacgtcagt
tcccaagttatttcacaacttaagcaaaagctcgaaaacctgcagaattcgaatctcccg
aagagctttagagtgccgtacgatcctggactgaaggcaggagcactagtgattgaaaaa
tgtaaagtgatggcctccaagaaaaagcccctgtggcttgagtttaaatgtgctgaccct
acagccctatccaatgaaacaattggaattatctttaaacacggtgatgatctgcgccaa
gacatgctgattttacagattctgcgaatcatggaatccatttgggagactgaatctttg
gatctgtgcctcctgccatatggttgcatttcaactggggacaaaataggaatgatcgag
atcgtgaaagatgccacaacaattgccaaaattcagcaaagtacagtgggcaatacgggc
gcgttcaaagatgaagtcctgaatcactggctcaaagaaaaatgccctattgaagagaag
ttccaggcagcagtggagagatttgtttattcctgcgctggctactgtgtggctaccttt
gttcttggaataggcgacaggcacaatgacaatattatgatcacagagacaggaaaccta
tttcatattgactttggacacattcttgggaattacaaaagtttcctgggcattaataaa
gaaagagtgccgtttgtgctaaccccagacttcctgttcgtgatgggaacttctggaaag
aagacaagcctacacttccaaaaatttcaggacgtctgtgtcaaggcttacctagccctt
cgtcaccacacaaatctgctgatcatcctgttctccatgatgctaatgacgggaatgccc
cagttaacaagcaaagaagacatcgaatatattcgggatgccctaacagtggggaagaac
gaggaggaagctaagaagtattttcttgatcagatcgaagtttgcagggacaaaggatgg
actgtgcagtttaactggttcctgcaccttgttctgggcatcaaacaaggagagaaacat
tcagcctaa

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