KEGG   Ailuropoda melanoleuca (giant panda): 100473675Help
Entry
100473675         CDS       T01329                                 

Gene name
PRF1
Definition
perforin 1 (pore forming protein)
Orthology
K07818  
perforin 1
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Natural killer cell mediated cytotoxicity
Type I diabetes mellitus
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:aml00001]
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100473675 (PRF1)
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    100473675 (PRF1)
   05330 Allograft rejection
    100473675 (PRF1)
   05332 Graft-versus-host disease
    100473675 (PRF1)
  Cardiovascular diseases
   05416 Viral myocarditis
    100473675 (PRF1)
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    100473675 (PRF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
Un
AA seq 554 aa AA seqDB search
MGARLFLPGLLLLLPTPTPAPCRTATRNECRSNRVFVPGTALAGEGVDVTTLKRSGSFPV
DTESFLRPDGTCTLCQNALQEDALQRLPLALTGWRAQGSGCQRQVVRAKASSTEGVAREA
ASNIRNDWRVGLDVSPKPSVNVQVTVAGSHSKMANFAAHKTHQDQYRFTTDLVECRFYSF
HLVHSPPLHPNFQRALSDLPPNFNTSTEADYLRLISSYGTHFIRSMELGGQISALTALRT
CELALDGLTASEVEDCLAVEAQVSISGRASSSSEFKACEEKKQQHKMETSFHQSYQERFS
QIVGGHHTSMGDLLFGTQAGPEQFSAWMNSLLDRPGLVDYTLEPLHVLVESKDPRREALR
QAVSKYVMDRARWKDCSRPCPPGQRKSPHNPCQCVCHSSATTNQDCCPRQRGLARLEVMN
FQATGLWGDNFTPTDAYLKVFFGGQELRTNTVWNNNHPKWMTRLDFGDVLLSMGGPLRVQ
VWDQDNGWDDDLLGTCDQKAQTGSHEVRCHLNHGHLRFSYQAKCLPHLEGPTCLQYAPHG
LLGAPPGNRSGPVW
NT seq 1665 nt NT seq  +upstreamnt  +downstreamnt
atgggcgcccgcctgttcctcccgggcctcctcctgctgctgcccacgcccaccccggcg
ccctgccgcacggccacccgcaatgagtgccggagcaaccgcgtgttcgtacccggcaca
gcgctggccggggagggcgtggacgtgaccaccctcaagcgctcgggctccttcccggtg
gacacagagagcttcctgcgccccgatggcacctgcaccctctgccagaatgccctgcag
gaggacgccctccaacgcctgcccctggcactgaccggctggcgcgcccagggctcaggc
tgccagcgccaagtggtcagggccaaggccagctccaccgaaggcgtggccagggaggcg
gccagcaacatccgcaacgactggcgggtggggctggatgtgtctcccaaacccagcgtc
aatgtgcaggtgaccgtggctggctcgcactccaagatggccaacttcgctgcccacaag
acccaccaggaccagtatcggttcaccactgacttggtggagtgtcgcttctacagtttt
cacctggtacactctcccccgctccaccccaacttccagagggccctcagcgacctgccc
cccaacttcaacacctccacagaggctgactacctcaggctcatctccagctacggcacc
cacttcatccggtccatggagctgggaggccagatctcggccctcactgccctgcgcacc
tgtgagctggccctggacgggctcacggccagcgaggtggaggactgcctggccgtcgag
gcccaggtcagcataagcggccgcgccagctcttcatcagaattcaaggcctgtgaggag
aagaagcagcagcacaagatggagacctccttccaccagtcctaccaggaacgcttttcc
caaatagttgggggccaccacacctccatgggcgacctgctgtttgggacacaggccggg
ccggagcagttctcagcctggatgaactcactgctggacagacccggcctggtggactat
accctggagcccctgcacgtgctcgtggagagcaaagacccccggcgggaggcgctgagg
caggccgtgagcaagtacgtgatggaccgggcccgctggaaggactgcagcaggccctgc
cccccggggcagcggaagagcccccacaacccatgccagtgcgtgtgccacagctcggca
accaccaaccaggactgctgcccccggcagaggggcctggcccgcttggaggttatgaac
ttccaggcgacaggcctgtggggagacaacttcacccccacagacgcctatctgaaagtc
ttctttggaggccaggagctgagaaccaacacggtgtggaacaataaccaccccaagtgg
atgacgcggctggacttcggggacgtgctcctgtccatgggggggcccctgagggtgcag
gtctgggaccaagacaatggctgggacgatgacctccttggcacctgtgaccagaaagca
cagactggctcccatgaggtgagatgccacctgaaccacggtcacctgagattctcctac
caggccaagtgcttgcctcacctggaggggcctacctgcctgcagtatgccccccacggt
cttttgggggcacctccaggaaaccggagcgggccagtgtggtga

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