KEGG   Ailuropoda melanoleuca (giant panda): 100474396Help
Entry
100474396         CDS       T01329                                 

Gene name
SOS2
Definition
son of sevenless homolog 2 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100474396 (SOS2)
   04010 MAPK signaling pathway
    100474396 (SOS2)
   04012 ErbB signaling pathway
    100474396 (SOS2)
   04630 Jak-STAT signaling pathway
    100474396 (SOS2)
   04068 FoxO signaling pathway
    100474396 (SOS2)
   04151 PI3K-Akt signaling pathway
    100474396 (SOS2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100474396 (SOS2)
  Cell communication
   04510 Focal adhesion
    100474396 (SOS2)
   04540 Gap junction
    100474396 (SOS2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100474396 (SOS2)
   04660 T cell receptor signaling pathway
    100474396 (SOS2)
   04662 B cell receptor signaling pathway
    100474396 (SOS2)
   04664 Fc epsilon RI signaling pathway
    100474396 (SOS2)
   04062 Chemokine signaling pathway
    100474396 (SOS2)
  Endocrine system
   04910 Insulin signaling pathway
    100474396 (SOS2)
   04912 GnRH signaling pathway
    100474396 (SOS2)
   04915 Estrogen signaling pathway
    100474396 (SOS2)
   04917 Prolactin signaling pathway
    100474396 (SOS2)
  Nervous system
   04722 Neurotrophin signaling pathway
    100474396 (SOS2)
  Development
   04320 Dorso-ventral axis formation
    100474396 (SOS2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100474396 (SOS2)
   05206 MicroRNAs in cancer
    100474396 (SOS2)
   05205 Proteoglycans in cancer
    100474396 (SOS2)
   05214 Glioma
    100474396 (SOS2)
   05221 Acute myeloid leukemia
    100474396 (SOS2)
   05220 Chronic myeloid leukemia
    100474396 (SOS2)
   05211 Renal cell carcinoma
    100474396 (SOS2)
   05215 Prostate cancer
    100474396 (SOS2)
   05213 Endometrial cancer
    100474396 (SOS2)
   05223 Non-small cell lung cancer
    100474396 (SOS2)
  Substance dependence
   05034 Alcoholism
    100474396 (SOS2)
  Infectious diseases
   05160 Hepatitis C
    100474396 (SOS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1378 aa AA seqDB search
MDFVLESFRQATSAVGQFVVLRPELQIFHHFHNSFKEILPPLGQKRSHVFLENLVVEVLD
YLSFLLLSGLRKVQEQVHPNLSANEESLYYIEELIFQLLNKLCMAQPRTVQDVEERVQKT
FPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGYKVDYHVSLYIVAVLEYI
SADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDIGLVSLCEDEPRSSGEL
NYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDIDRIFSNISDIHELTVKL
LGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILSPKFNEHFSKLMARPA
VALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKACSEEQEDRECLNQAITA
LMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIGQ
CCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPGYSSAEYRLKEKFVMRKI
QICDKEDTCECKHAFELVSKDENSIVFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLL
KEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYA
DPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLAVEKGEQPISADLKRFRK
EYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIKR
KKQAQANGISHNITFESPPPPTEWHISRPGQFETFDLMTLHPIEIARQLTLLESDLYRKV
QPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAILSRIIEIL
QVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILDEAVELSQDHFKKYLVKL
KSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPY
CLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPG
IRPNTGRHGSTSGTLRGHPTPLEREPCKMSFSRIAETDIESTVSAPTSPNTPSTPPVSAS
SDLSVFLDVDLSSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFED
DASNSKGNTKSDDDPPAIPPRQPPPPKVKPRAPAPTGAFDGPLHSPPPPPPRDPLPDTPP
PVPLRPPEHFLNCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPNTPPSTPSPRVPRRCYVL
SSSHNHLAHPQAPPVPPRQSSSPHLPNLPKLPPKTYKRELSHPPSFRLPVLENAETPQ
NT seq 4137 nt NT seq  +upstreamnt  +downstreamnt
atggatttcgtgttggagtcgtttcgtcaggcaacttccgccgttggccaatttgttgtc
ctcaggccggagttacagattttccatcattttcataattctttcaaggagatattgcct
cccttgggccaaaaacgaagtcatgtttttttagagaacttggtggtggaggtcttagac
tatttaagttttctattactttctgggttaagaaaagttcaggagcaagtacatcccaat
ctctcagctaatgaagagtctctctattatattgaagagctgatttttcagctgcttaat
aaattatgcatggctcaaccaaggactgttcaagatgtggaggaacgtgttcaaaagacc
tttcctcatccaattgataaatgggctattgctgatgcacaatctgccatagaaaaacga
aaacgaagaaatcctctcttacttcctgtggacaaaatccatccttcattgaaggaagtt
ttagggtacaaagtggactatcatgtatccctatatattgtggctgtgctagagtatatc
tcagctgatattttgaagttggctggtaattatgtttttaatatccgacattatgaaata
tctcagcaggacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgat
caggatgacataggtttggtttctctctgtgaagacgaacctcgttcttcaggcgaatta
aactactatgaccttgtcagaaccgaaattgcggaagaaaggcagtatctacgggaactc
aatatgatcattaaagtgtttcgagaagcctttctttctgacagaaagctgtttaaacct
tctgatattgacaggattttcagtaacatttcagatatacatgaattaactgtgaaactt
ttaggtttgattgaagacacagttgaaatgactgatgaaagcagtcctcatccgttagcg
ggcagctgttttgaagatttggcagaagagcaagcatttgatccttatgaaacattatca
caggacattctttctccaaaatttaatgaacattttagtaagttgatggccagacctgcg
gtggctctacactttcagtccattgctgatggttttaaagaggcagttcgttatgtcctt
ccacgccttatgctggtgcctgtttatcattgttggcactattttgaattattaaagcaa
ttgaaagcatgtagtgaagagcaggaagacagagaatgtttgaaccaagctattaccgct
cttatgaatctccaaggtagtatggaccggatttacaagcagtattcacctagacgccga
cctggggatcctgtttgccctttttataatcgtcagttaagaagcaagcatctggctatt
aaaaaaatgaatgaaattcagaaaaacatagatggatgggaagggaaagatattggacag
tgttgtaatgaattcattatggaaggcccattgacacgaattggtgctaaacatgaacga
catatttttctcttcgatggcttaatgattagctgtaaacccaatcatagtcagtcacgc
cttccaggttatagtagtgcagaatacagattaaaagagaaatttgtcatgaggaaaata
caaatatgtgataaagaagatacttgtgagtgcaaacatgcttttgagttggtatccaaa
gatgaaaacagcatagtatttgctgctaagtctgccgaagagaaaaacaattggatggcc
gcacttatttctcttcactatcgtagtacactagatcgaatgctagattcagtgttattg
aaagaagaaaatgagcaaccattgagattaccaagtcctgaagtgtatcgttttgtggta
aaagactctgaggaaaacattgtttttgaagacaacctgcaaagtagaagtggaatcccc
attattaaaggaggaactgtagtgaaattaattgaaaggttaacatatcatatgtatgca
gatcccaattttgttcgtacttttcttactacataccgttcattttgtaaaccacaggaa
ttgctaagcttactgattgaacgatttgaaattccagagccagaacctactgaagcagat
aaattggccgtagagaaaggcgaacagccgatcagcgcagaccttaaaaggtttcgcaag
gaatatgtgcaaccagtacagcttaggatcttaaatgtgtttcggcactgggttgaacac
catttttatgactttgaaagggatttggagttgcttgaaagactagaatccttcatttca
agtgtaagagggaaagctatgaagaagtgggtagagtcaattgctaagatcatcaagaga
aagaaacaagctcaggcaaatggaataagccataatattacctttgaaagtccacctcca
ccaactgaatggcatatcagcagaccagggcagtttgaaacatttgacctcatgaccctt
catccaatagaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagtc
caaccttctgaactagtagggagtgtatggacgaaagaagataaagaaataaattctcca
aatttgttaaaaatgattcgccataccacaaacctcaccttatggtttgaaaagtgtatt
gtggaagcagaaaattttgaggaacgggtggcaatactaagtagaattatagaaattctg
caagtttttcaagatttgaataacttcaatggtgtattggagatagtcagtgcagtaaat
tcagtgtcggtatacagactagaccatacttttgaggcattgcaggaaagaaaaaggaga
attttggatgaagctgtggaattaagtcaagatcactttaaaaaatacctggtaaaactt
aagtcaatcaatccaccttgcgtgcctttttttggaatatatttaacaaatattctgaaa
actgaagaagggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagt
aagaggaggaaagtagctgaaattactggagaaattcagcagtatcagaatcaaccttac
tgtttacggatagaaccagaaatgaggaggttctttgaaaaccttaaccccatgggaagt
gcttctgaaaaggagtttacggattatttgttcaacaaatcactagaaattgaaccccga
aactgcaaacagccacctcgatttcctaggaaatcaactttctctttaaaatctcctgga
atacggcctaatacaggccgacatggctctacctcaggcactttacgaggtcatccaacg
ccattagaaagagaaccatgtaaaatgagctttagtcggattgctgaaactgatattgaa
tcaacggtgtcagcaccgacctctccaaatacaccatctactccaccagtatctgcttct
tcagaccttagtgtgtttttggatgtggatctcagcagttcctgtggcagcaatagcatc
tttgctccagtcctcttgccacattcaaaatctttcttcagctcctgtggtagtttacat
aaactgagtgaagagccgctgatcccccctccgcttcctcctcgaaaaaagtttgaggac
gatgcttcaaactccaagggaaatacgaaatctgatgatgacccccctgctattccacca
agacagcctcctcctccaaaggtaaaacccagagctcctgctcctactggtgcatttgac
gggcctctgcacagtccacctccaccgccaccaagagaccctcttcctgatacccctcca
ccagttccccttcggcctccagagcactttctaaactgcccgtttaatcttcagccacct
ccactaggacatctgcacagagacccagactggttcagagatgttagtacctgcccaaac
tcgccaaatactcctcctagcacaccctctccgagagtaccacgtcgatgctacgtgctc
agttctagtcacaaccaccttgctcatcctcaagctccccctgttccaccgaggcagagt
tcaagccctcacctgccaaacctaccaaaactgccaccaaagacttacaaacgggagctt
tcgcaccctccgtcattcagactgcctgtgctagaaaatgcggaaactcctcagtga

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