KEGG   Ailuropoda melanoleuca (giant panda): 100474543Help
Entry
100474543         CDS       T01329                                 

Gene name
SYK
Definition
(RefSeq) spleen associated tyrosine kinase
  KO
K05855  
spleen tyrosine kinase [EC:2.7.10.2]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
NF-kappa B signaling pathway
Phospholipase D signaling pathway
PI3K-Akt signaling pathway
Osteoclast differentiation
Platelet activation
Natural killer cell mediated cytotoxicity
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Tuberculosis
Kaposi's sarcoma-associated herpesvirus infection
Epstein-Barr virus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:aml00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    100474543 (SYK)
   04072 Phospholipase D signaling pathway
    100474543 (SYK)
   04151 PI3K-Akt signaling pathway
    100474543 (SYK)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100474543 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    100474543 (SYK)
   04662 B cell receptor signaling pathway
    100474543 (SYK)
   04664 Fc epsilon RI signaling pathway
    100474543 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    100474543 (SYK)
  Development
   04380 Osteoclast differentiation
    100474543 (SYK)
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    100474543 (SYK)
  Infectious diseases
   05152 Tuberculosis
    100474543 (SYK)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    100474543 (SYK)
   05169 Epstein-Barr virus infection
    100474543 (SYK)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100474543 (SYK)
Protein kinases [BR:aml01001]
 Tyrosine protein kinases
  Syk family
   100474543 (SYK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 471 aa AA seqDB search
MPWFHGKISRVESEQIVMIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGK
LSIPDGKKFDTLWQLVEHYSYKPDGLLRVLTVPCQKIGGQAGNINFGARAPLPGAHPATW
SAGAIISRIKSYSFPKPGHRKASSSTGSRPESSVTFNPYEPDRGPWATDRDAQREAMPMD
TEVYESPYADPEEIRPKEVYLDRKLLTLEDSELGSGNFGTVKKGYYQMKKVVKTVAVKIL
KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR
HVKDKNIIELVHQVSMGMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN
YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAM
LEKGERMGCPAGCPREMYELMKLCWTYEVEKRPGFENVELRLRNYYYDVVN
NT seq 1416 nt NT seq  +upstreamnt  +downstreamnt
atgccctggttccacggaaaaatctcacgggttgaatctgagcaaattgtcatgatagga
tccaagacaaatggaaaatttttgatcagggacaggaacgacaacgggtcttacgccctg
tgcctgctgcacgaggggaaggtgttgcactatcgcatcgacaaggacaaaaccgggaag
ctctccatccccgatgggaagaagttcgacacgctctggcagctcgtggagcattactct
tacaaaccggacgggctgttgagagttcttacggttccgtgccagaaaattggcgggcag
gcaggaaacatcaactttggagcccgcgcgcccctgccaggcgcccaccctgcgacgtgg
tcagctggtgcgataatctccagaatcaaatcctactccttcccaaagcccggccacaga
aaggcctcctcgtccacagggagccggcccgagagctccgtgaccttcaatccttatgag
ccagaccgggggccctgggccacggacagagatgcgcagagagaagccatgcccatggac
accgaggtgtacgaaagcccctacgccgaccccgaggagatcaggcccaaggaggtctac
ctggaccgcaagctgctgaccctggaggacagtgagctgggctctgggaacttcgggacc
gtgaagaagggctactaccagatgaaaaaagtcgtgaagacagtggctgtgaagattttg
aagaacgaggccaatgaccctgctctcaaagatgagttattagcagaagcgaacgtcatg
cagcagctcgataacccttacatcgtgcgcatgatcgggatatgtgaagccgagtcctgg
atgctggtcatggagatggcagagctgggtccactcaataaatacttacagcagaacagg
cacgtcaaggataagaacatcatagagctggttcatcaggtttctatgggaatgaaatat
ctggaggagtgcaattttgtgcacagagatctggctgcaagaaatgtattgctggttact
caacattatgccaagattagtgatttcggactttccaaagcactccgtgctgacgaaaac
tactataaggcgcagacccacggaaagtggccggtgaagtggtacgctccggagtgcatt
aactactacaagttctccagcaagagcgacgtctggagcttcggtgtgctgatgtgggag
gcgttctcctacgggcagaagccctaccggggcatgaaaggaagtgaagtttcggctatg
ctggagaaaggggagaggatggggtgccccgcgggatgtccaagggagatgtacgagctg
atgaagctgtgctggacatatgaggtggagaagaggcccggcttcgaaaacgtggagctg
cggctgcgcaattactactacgacgtggtgaactaa

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