KEGG   Ailuropoda melanoleuca (giant panda): 100474779Help
Entry
100474779         CDS       T01329                                 

Gene name
PLCB2
Definition
phospholipase C, beta 2
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:aml00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100474779 (PLCB2)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100474779 (PLCB2)
   04310 Wnt signaling pathway
    100474779 (PLCB2)
   04020 Calcium signaling pathway
    100474779 (PLCB2)
   04070 Phosphatidylinositol signaling system
    100474779 (PLCB2)
   04022 cGMP - PKG signaling pathway
    100474779 (PLCB2)
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    100474779 (PLCB2)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100474779 (PLCB2)
   04062 Chemokine signaling pathway
    100474779 (PLCB2)
  Endocrine system
   04911 Insulin secretion
    100474779 (PLCB2)
   04912 GnRH signaling pathway
    100474779 (PLCB2)
   04915 Estrogen signaling pathway
    100474779 (PLCB2)
   04921 Oxytocin signaling pathway
    100474779 (PLCB2)
   04918 Thyroid hormone synthesis
    100474779 (PLCB2)
   04919 Thyroid hormone signaling pathway
    100474779 (PLCB2)
   04916 Melanogenesis
    100474779 (PLCB2)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100474779 (PLCB2)
   04270 Vascular smooth muscle contraction
    100474779 (PLCB2)
  Digestive system
   04970 Salivary secretion
    100474779 (PLCB2)
   04971 Gastric acid secretion
    100474779 (PLCB2)
   04972 Pancreatic secretion
    100474779 (PLCB2)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100474779 (PLCB2)
  Nervous system
   04724 Glutamatergic synapse
    100474779 (PLCB2)
   04725 Cholinergic synapse
    100474779 (PLCB2)
   04728 Dopaminergic synapse
    100474779 (PLCB2)
   04726 Serotonergic synapse
    100474779 (PLCB2)
   04720 Long-term potentiation
    100474779 (PLCB2)
   04730 Long-term depression
    100474779 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    100474779 (PLCB2)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100474779 (PLCB2)
  Environmental adaptation
   04713 Circadian entrainment
    100474779 (PLCB2)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100474779 (PLCB2)
   05016 Huntington's disease
    100474779 (PLCB2)
  Infectious diseases
   05146 Amoebiasis
    100474779 (PLCB2)
   05142 Chagas disease (American trypanosomiasis)
    100474779 (PLCB2)
   05143 African trypanosomiasis
    100474779 (PLCB2)
Enzymes [BR:aml01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100474779 (PLCB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
Un
AA seq 1100 aa AA seqDB search
MSLLNPVLLPPKVKAYLSQGERFIKWDDETTIASPVILRVDPKGYYLYWTYQSKEMEFLD
ITSIRDTRFGKFAKIPKSQKLRDVFNMDFPDNNFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVGQNWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKR
VEAALSACHLPKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEH
LTKFINQKQRDPRLNSLLFPPARPDQVRGLIDKYEPSGINVQRGQLSPEGMVWFLCGPEN
SVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDC
WKGKPPDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKM
AEYCRMMFGDMLLTEPLEKFPLKPGIPLPSPEALRGKILIKNKKNQFSGPAAPSEEPGEE
AEGNCPPNASVGEDTVWAGEEGAEPEEEEEEEEEEEEESGNLDEEEIKKMQSDEGTAGLE
VTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYVISSFTELKAYELLSKASVQFVDYNKRQ
MSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHE
FMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSDRSVRTYVEVELFGLPGDPKRRYR
TKLSPSANSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHH
LCLHSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKFFSAHDKKSVKLKEAMGG
LPEKPFPLGSPVVGPVNGTLAPTSNGSAAAGARAKQEATKEGAEPRTXXXXXXXXXVVKL
QRRHEKELRDLERRGARRWEELLQRGAQIAKMMELAREKQAAELKTLKETLETDTKEMKK
KLEAKRLERIQAMVKVTSDKMAQERLKREINNSHIQEVVQVIKQMTENLEKHQEKLEEKQ
AACLEQIREMEKQFQQEALAEYEARMKGLEAEVKESVKACLRDCLPSEAKDDPERPCEAF
RELCEQDPLTVKTGAQESRL
NT seq 3303 nt NT seq  +upstreamnt  +downstreamnt
atgtctctgctcaacccggtcctgctgccccccaaggtgaaggcttatctgagccaaggg
gagcgcttcatcaaatgggacgatgaaactacaatagcctccccggttatcctccgtgtg
gatcccaagggctactacttatattggacatatcagagtaaggagatggagtttctggat
atcaccagcatcagggatacccgctttgggaagtttgccaagatacccaagagccagaag
ctccgggatgtcttcaacatggacttccctgacaacaacttcctgctgaagacgctcact
gtggtgtccggccctgacatggtggacctcaccttccacaacttcgtctcctacaaggag
aatgtgggccagaactgggccgaagatgtgctggctctggtcaagcacccgctgacagcc
aatgcctcccgcagcaccttcttggacaaaatcctggtaaagctcaagatgcagctcaac
cccgaagggaagattcctgtgaaaaattttttccagatgtttcctgctgaccgcaagcgg
gtggaagctgccctcagcgcctgccacctcccaaaaggcaagaatgatgccatcaatcct
gaggacttcccagaatccgtctacaagagtttcctcatgagcctctgtcctcggccagaa
atagacgagatcttcacttcctaccatgccaaggccaaaccctacatgaccaaggagcac
ttgaccaagttcatcaaccagaaacagagggacccccgtctcaactctttgctgtttcca
ccggcacggcctgaccaggtgcggggcctcatcgacaagtatgagcccagtggcatcaac
gtgcagaggggccagctctccccagagggcatggtgtggtttctctgcgggcccgagaac
agcgtgctggcccaggacaagctgctgctccaccacgacatgactcagccactcaaccat
tacttcatcaactcctcacacaacacctacctgacagccggccagttctctggcctttcc
tcggccgagatgtaccgccaggtgctgctcgctggctgccgctgtgtggagctggactgc
tggaagggcaagccccctgacgaggagcccattatcacccacggcttcaccatgaccacg
gacatctacttcaaggaagcaattgaagccatcgcagaaagtgcctttaagacctccccc
tatcctgtcatcctatcatttgaaaaccatgtggactcaccccgccaacaggccaagatg
gctgaatactgccggatgatgtttggggatatgctgctcacagagcccctggaaaagttc
ccgttgaaaccaggcatccccctgccaagccctgaggctctccgaggcaagatcctcatc
aagaacaaaaagaaccagttttctggcccagcagcccccagcgaggagccgggagaggag
gctgagggcaactgcccacccaacgcctctgtgggggaggacacagtgtgggctggcgag
gaaggggcagagccggaggaggaagaggaggaagaggaggaggaggaggaagagtcggga
aacctggatgaggaggagatcaagaagatgcagtcggatgagggtacagcgggcctggag
gtgacagcttatgaggagatgtccagcctagtgaattacatccagcccaccaagttcatc
tcctttgagttctctgcccagaagaaccgaagttatgtcatctcgtccttcacagagctc
aaggcctatgagctgctctccaaggcctcagtgcagtttgtggactacaacaagcgccag
atgagccgcatttaccctaagggcacccgcatggactcctccaactacatgccccagatg
ttctggaacgccggttgccagatggttgccctcaacttccagacgatggacctgcccatg
cagcagaacatggcgctgtttgagttcaatgggcagagtggctacctcctcaagcatgag
ttcatgcggcggccagacaagcagttcaaccccttctccgtggaccgcatcgacgtggtg
gtagccaccaccctttccatcacggtgatctctgggcagttcctgtcggatcgcagtgtg
cgcacgtatgtggaagtggaactgtttggccttcctggggaccccaagaggcgctatcgc
accaagctgtcacccagcgccaactccatcaatcctgtctggaaggaggagccttttgtc
tttgagaagatcttgatgcccgagctggcctccctcagggtggctgtaatggaagaaggc
aacaaatttcttggacaccgcattatccccattaacgccctgaattctggctaccaccac
ctgtgcctgcacagcgagagcaacatgccccttaccatgcctgcactttttgtcttcctg
gagatgaaggactatgtgcctgacacctgggcagatctcaccgtagctctcgccaatccc
atcaagttcttcagtgcccatgataagaagtctgtgaagctcaaggaagccatgggaggt
ctgcctgagaaacccttcccacttgggagtccagttgtcggcccggtcaacgggacattg
gccccgacgagcaacgggtctgcagcagccggggccagggccaagcaggaggccacgaaa
gaaggtgcggagccgcggaccnnnnnnnnnnnnnnnnnnnnnnnnngcgtcgtgaagctg
cagcggcggcacgagaaggagctgcgggacctggagcggcgcggcgcgcggcgctgggag
gagctgctgcagaggggcgcgcaaatcgccaagatgatggagctggccagagagaagcag
gctgcagagctgaagaccctcaaggagaccttggagactgacaccaaagagatgaagaaa
aagctggaggccaagaggctggagcggattcaggccatggtcaaagtcacctcagacaag
atggctcaggaaaggctgaagagagagattaacaactctcacatccaggaggtggtgcaa
gtcattaagcagatgacagagaacctggaaaagcaccaggagaagctagaggagaagcag
gcagcctgcctggaacagatccgggagatggaaaagcagttccagcaggaggcgctggca
gagtacgaggccaggatgaagggcctggaggctgaggtgaaggagtcagtgaaggcctgc
ctcagggactgcttaccctctgaggccaaggacgatcctgagaggccctgtgaggccttc
agggagctgtgtgagcaggacccactcacagtaaagacgggcgcccaggagagccgcctc
tga

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