KEGG T01329: 100477081

Ailuropoda melanoleuca (giant panda): 100477081

Entry

100477081 CDS T01329

Gene name

ARHGEF1

Definition

Rho guanine nucleotide exchange factor (GEF) 1

Orthology

K12330

Rho guanine nucleotide exchange factor 1

Organism

aml Ailuropoda melanoleuca (giant panda)

Pathway

aml04270	Vascular smooth muscle contraction
aml04810	Regulation of actin cytoskeleton
aml05205	Proteoglycans in cancer

Class

Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:aml04810]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:aml04270]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:aml05205]

SSDB

Motif

Pfam:

RGS-like RhoGEF PH_5

Other DBs

NCBI-GI:

301777147

NCBI-GeneID:

100477081

Position

AA seq 911 aa
MEAEDVARGLAPGPPRPGLVPVSIIGAEDEDFENELETNAEEQNSQFQSLEQVKRRPAHL
MALLQHVALQFEPGPLLCCLHADMLASLGPKEAKKAFLDFYHSFLDKTAVLRVQVPPTVA
FELDRTRPDLLSEDVQRQFVQEVVQSQQAAVSRLLEDFRSKRLMGMTPWEHDLTQLEAWV
GRDRASFEARERHLAERLLSHPDLEEMQHTISTDEEKSAAVVNAISLYMRHLGVRTKSGD
KKSGRNFFRKKMMGNRRSDEPTKSKKGLSIFLDAARWNRGEPQAPDFRHLKVEADAEKPG
LTEKRGGLGVPSRDRNFGAPGQDVPGVSLHPLSGDSPDREPGLDATPELGDPPPQGPASL
EPLVPPESTEEGADTESPEPGDEGDPGRSGLELEPEEPPGWRELVPVGTLHSLPKSQVKR
QEVISELLVTEAAHVRMLRVLHDLFYQPMAEGGFFSQEELQNIFPSLDELIEVHSLFLDR
LMKRRQDSGYLIEEIGDVLLARFDGAEGKWFQKISSRFCSRQSFALEQLKVKQRKEPRFC
AFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPVERERVELAAECCRE
ILHHVNQAVRDMEDLLRLKDYQKRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWR
VTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTRE
VATDHKAFYVIFTWDQEAQIYELVAQTVSERKNWCSLITDTAGSLKVPAPASRPKSRPSP
SSTREPLLSSSENGNGGGREIPPGDGRMERILSALLPYCRPVPEGQLAAKALEKVLSLKQ
LLFPSEEDSGAGPPREGDGVPGGGSQSPTQTQEIREKLLSLEEQEVEEEFCRLRLLLSQL
GENSVQQPGCT

NT seq 2736 nt +upstreamnt +downstreamnt
atggaggcagaggacgtcgcccgcgggctggccccaggaccaccgcggcctggcctggtg
ccagtcagcatcatcggggctgaggatgaggattttgagaatgagctggagacgaacgca
gaggagcaaaacagccagttccagagcctggagcaggtgaagcggcggcctgcccacctc
atggcgctcctgcagcacgttgccctgcagtttgaaccgggacccctgctctgctgcctt
cacgcggatatgctggcttccctgggccccaaggaggccaagaaggccttcctcgacttc
taccatagctttctggacaagaccgcggttttgcgggtacaagtccctcccactgtcgcc
tttgaacttgaccgcacgcggcccgacctcctctctgaggacgtccagcggcagttcgtg
caggaggtggtgcagagccagcaggccgccgtcagccggctgctggaggacttccgctcc
aagcggctcatgggcatgacgccctgggagcatgacctgacccagctggaggcctgggtt
gggcgggaccgggccagctttgaggcgcgggagcggcacttggccgagcggctgctgagc
cacccagacctagaggagatgcaacacaccatctctaccgatgaggaaaagagtgccgct
gtggtcaacgcgatcagcctgtacatgcgccaccttggggtgcggaccaagagcggggac
aagaagtcggggaggaatttcttccgaaaaaagatgatgggcaatcgacggtcagatgag
ccaaccaagagcaagaaaggcctgagcatcttcctggacgctgcccgctggaaccgggga
gagcctcaggccccagatttccgacacctcaaagtcgaggctgatgctgagaagccaggc
cttacggaaaagaggggaggcctgggggtgccctcccgggaccggaactttggggctcct
gggcaggatgtccctggagtttctctgcaccctctatctggagatagccctgaccgggaa
ccaggtcttgatgccacaccagagctgggggacccgcccccacagggcccggccagcctg
gagcccctggtacccccggagagcaccgaggagggtgctgacacagagagccctgagcct
ggagacgaaggggacccgggacggtcaggactagagctggaaccagaagagccccctggc
tggcgggagctcgtcccagttggcaccctgcacagcctgcctaagagccaggtgaagcgg
caggaggtcatcagcgagctgctggtgacagaggccgcccacgtgcgcatgctccgggtg
ctgcatgacctcttctaccagcccatggcagaagggggcttcttctcccaggaggagcta
cagaacatctttcccagcctggacgagctcatcgaggtgcattccctgttcctcgatcgg
ctgatgaagcggaggcaggatagtggctacctcattgaggagatcggagacgtactgctg
gcccggtttgatggtgccgaaggcaaatggttccagaaaatctcctcccgcttctgcagc
cgccagtcgtttgccttagagcagctcaaagtcaagcagcgcaaggagcctcggttctgt
gccttcgtgcaggaggcggagagccgcccgcggtgccgccgcctgcagctgaaggatatg
atccccacggagatgcagcggctgaccaagtaccccctgctcctgcagagcatcgggcag
aacacagaagagccggtggaacgggagagagtggaactggcagccgagtgctgccgggag
attctgcaccatgtgaaccaagccgtgcgtgacatggaggacctgctgcggctcaaggat
tatcagaagcgcctggacttgtcccacctgcggcagagcagcgaccccatgctgagcgag
ttcaagaacctggacatcaccaagaagaagctggtgcacgagggcccgctgacgtggcgg
gtgacgaaggacaaggctgtagaggtccacgtgctgctgctggacgacctgctgctgctg
ctccagcgccaagacgagcggctgctgctcaagtcccacagccggacgctgacgcccacg
cccgatggcaagaccatgctgcggcccgtgctgcggctcacgtccgccatgacccgcgag
gtggctaccgatcacaaagccttctatgtcatttttacgtgggaccaagaagcccagata
tatgaactggtggcccagaccgtgtcggaacgaaaaaactggtgttccctcatcaccgac
actgctggatccttgaaggtccctgctcccgcctctcgccccaaatcccggcccagccct
agcagcacacgagaacccctgctcagcagctcggagaatggcaacgggggtggccgagag
atacccccaggggacggccgaatggagagaatcctcagcgccctcctgccctactgcagg
cccgtccccgagggccagcttgctgccaaggcccttgagaaagtgctatccctgaagcag
ctcctgtttccctcggaggaagacagtggggcagggcctccccgtgaaggggatggggtc
ccagggggtggctcccagagcccgacccagacccaggagattcgggagaagctgctcagc
ctggaggagcaggaggtggaggaggaattttgtcgcctgcggctcctcctgtctcagctt
ggggagaacagcgtccagcagcctggctgtacctga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (13)   

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