KEGG   Ailuropoda melanoleuca (giant panda): 100477081Help
Entry
100477081         CDS       T01329                                 

Gene name
ARHGEF1
Definition
(RefSeq) Rho guanine nucleotide exchange factor (GEF) 1
  KO
K12330  
Rho guanine nucleotide exchange factor 1
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Vascular smooth muscle contraction
Platelet activation
Regulation of actin cytoskeleton
Pathways in cancer
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100477081 (ARHGEF1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100477081 (ARHGEF1)
  Circulatory system
   04270 Vascular smooth muscle contraction
    100477081 (ARHGEF1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100477081 (ARHGEF1)
   05205 Proteoglycans in cancer
    100477081 (ARHGEF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
Un
AA seq 985 aa AA seqDB search
MPSTLLSASPVEPMEAEDVARGLAPGPPRPGLVPVSIIGAEDEDFENELETNAEEQNSQF
QSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLASLGPKEAKKAFLDFYHSFLDK
TAVLRVQVPPTVAFELDRTRPDLLSEDVQRQFVQEVVQSQQAAVSRLLEDFRSKRLMGMT
PWEHDLTQLEAWVGRDRASFEARERHLAERLLSHPDLEEMQHTISTDEEKSAAVVNAISL
YMRHLGVRTKSGDKKSGRNFFRKKMMGNRRSDEPTKSKKGLSIFLDAARWNRGEPQAPDF
RHLKVEADAEKPGLTEKRGGLGVPSRDRNFGAPGQDVPGVSLHPLSGDSPDREPGLDATP
ELGDPPPQGPASLEPLVPPESTEEGADTERRWKRLSGRLGRSESLRVSDRRRPSRGSLGA
KGRGGGRSRSDVDMDPSSATAVLGPARRATPEPGDEGDPGRSGLELEPEEPPGWRELVPV
GTLHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFYQPMAEGGFFSQEELQNIFPSL
DELIEVHSLFLDRLMKRRQDSGYLIEEIGDVLLARFDGAEGKWFQKISSRFCSRQSFALE
QLKVKQRKEPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPVE
RERVELAAECCREILHHVNQAVRDMEDLLRLKDYQKRLDLSHLRQSSDPMLSEFKNLDIT
KKKLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTML
RPVLRLTSAMTREVATDHKAFYVIFTWDQEAQIYELVAQTVSERKNWCSLITDTAGSLKV
PAPASRPKSRPSPSSTREPLLSSSENGNGGGREIPPGDGRMERILSALLPYCRPVPEGQL
AAKALEKVLSLKQLLFPSEEDSGAGPPREGDGVPGGGSQSPTQTQEIREKLLSLEEMEEV
EEEFCRLRLLLSQLGENSVQQPGCT
NT seq 2958 nt NT seq  +upstreamnt  +downstreamnt
atgcctagcacactgttaagtgctagccctgtggagcccatggaggcagaggacgtcgcc
cgcgggctggccccaggaccaccgcggcctggcctggtgccagtcagcatcatcggggct
gaggatgaggattttgagaatgagctggagacgaacgcagaggagcaaaacagccagttc
cagagcctggagcaggtgaagcggcggcctgcccacctcatggcgctcctgcagcacgtt
gccctgcagtttgaaccgggacccctgctctgctgccttcacgcggatatgctggcttcc
ctgggccccaaggaggccaagaaggccttcctcgacttctaccatagctttctggacaag
accgcggttttgcgggtacaagtccctcccactgtcgcctttgaacttgaccgcacgcgg
cccgacctcctctctgaggacgtccagcggcagttcgtgcaggaggtggtgcagagccag
caggccgccgtcagccggctgctggaggacttccgctccaagcggctcatgggcatgacg
ccctgggagcatgacctgacccagctggaggcctgggttgggcgggaccgggccagcttt
gaggcgcgggagcggcacttggccgagcggctgctgagccacccagacctagaggagatg
caacacaccatctctaccgatgaggaaaagagtgccgctgtggtcaacgcgatcagcctg
tacatgcgccaccttggggtgcggaccaagagcggggacaagaagtcggggaggaatttc
ttccgaaaaaagatgatgggcaatcgacggtcagatgagccaaccaagagcaagaaaggc
ctgagcatcttcctggacgctgcccgctggaaccggggagagcctcaggccccagatttc
cgacacctcaaagtcgaggctgatgctgagaagccaggccttacggaaaagaggggaggc
ctgggggtgccctcccgggaccggaactttggggctcctgggcaggatgtccctggagtt
tctctgcaccctctatctggagatagccctgaccgggaaccaggtcttgatgccacacca
gagctgggggacccgcccccacagggcccggccagcctggagcccctggtacccccggag
agcaccgaggagggtgctgacacagagagaaggtggaagaggctatcggggcgtctgggg
cgctcggagagcctgcgggtgagtgaccgccgccggccttcccggggcagcctcggggct
aagggccggggtgggggccgctcccggagtgacgtggacatggaccccagctctgccacg
gccgtgcttggccctgcccgacgagccacccctgagcctggagacgaaggggacccggga
cggtcaggactagagctggaaccagaagagccccctggctggcgggagctcgtcccagtt
ggcaccctgcacagcctgcctaagagccaggtgaagcggcaggaggtcatcagcgagctg
ctggtgacagaggccgcccacgtgcgcatgctccgggtgctgcatgacctcttctaccag
cccatggcagaagggggcttcttctcccaggaggagctacagaacatctttcccagcctg
gacgagctcatcgaggtgcattccctgttcctcgatcggctgatgaagcggaggcaggat
agtggctacctcattgaggagatcggagacgtactgctggcccggtttgatggtgccgaa
ggcaaatggttccagaaaatctcctcccgcttctgcagccgccagtcgtttgccttagag
cagctcaaagtcaagcagcgcaaggagcctcggttctgtgccttcgtgcaggaggcggag
agccgcccgcggtgccgccgcctgcagctgaaggatatgatccccacggagatgcagcgg
ctgaccaagtaccccctgctcctgcagagcatcgggcagaacacagaagagccggtggaa
cgggagagagtggaactggcagccgagtgctgccgggagattctgcaccatgtgaaccaa
gccgtgcgtgacatggaggacctgctgcggctcaaggattatcagaagcgcctggacttg
tcccacctgcggcagagcagcgaccccatgctgagcgagttcaagaacctggacatcacc
aagaagaagctggtgcacgagggcccgctgacgtggcgggtgacgaaggacaaggctgta
gaggtccacgtgctgctgctggacgacctgctgctgctgctccagcgccaagacgagcgg
ctgctgctcaagtcccacagccggacgctgacgcccacgcccgatggcaagaccatgctg
cggcccgtgctgcggctcacgtccgccatgacccgcgaggtggctaccgatcacaaagcc
ttctatgtcatttttacgtgggaccaagaagcccagatatatgaactggtggcccagacc
gtgtcggaacgaaaaaactggtgttccctcatcaccgacactgctggatccttgaaggtc
cctgctcccgcctctcgccccaaatcccggcccagccctagcagcacacgagaacccctg
ctcagcagctcggagaatggcaacgggggtggccgagagatacccccaggggacggccga
atggagagaatcctcagcgccctcctgccctactgcaggcccgtccccgagggccagctt
gctgccaaggcccttgagaaagtgctatccctgaagcagctcctgtttccctcggaggaa
gacagtggggcagggcctccccgtgaaggggatggggtcccagggggtggctcccagagc
ccgacccagacccaggagattcgggagaagctgctcagcctggaggagatggaggaggtg
gaggaggaattttgtcgcctgcggctcctcctgtctcagcttggggagaacagcgtccag
cagcctggctgtacctga

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