KEGG   Ailuropoda melanoleuca (giant panda): 100479318Help
Entry
100479318         CDS       T01329                                 
Gene name
PLCE1
Definition
phospholipase C, epsilon 1
Orthology
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Calcium signaling pathway
Phosphatidylinositol signaling system
Proteoglycans in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:aml00562]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:aml04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:aml04070]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:aml05205]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
Un
AA seq 2301 aa AA seqDB search
MTSEEMAASVLTPVTQRRVTSTPSAIDESSEKVLDVSVPKAHSVRQSRQTSTIPQMNKLK
EEPSGSNLPKILSIAREKTVSNENSSEKCWAESTPVSVKNLNINHNNILTNHQCVLPQSQ
CYDTCDSVMEEDPCSETGIPSSLERKAFPGIQLEIDGPPMDISPSGSQLAIVETGQAHPD
GNTAAFHFHYGVDKTVSDAVCTLSGNLILDDCGNCVQLPGVGGEQKKNYVAYTCKLMELA
ENCDNKNGQLQCDHCDTLDDKYLCLEGSCQRASVVCSSDSFCREDLTNSPPAKTFLSHFE
DFPDNCEDVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLGAY
SYIDQKRSGPLLPCGRVLERLSVVAIRQDGSQCLSEAQWYQIYNAVRRGEEIENTIGSRL
HVFTKLPASETTHERISVGPCLKQCVRDTICEYRATLQRTSISQYITGSLLEATTSLGAR
SGLLNTFGGSTGRMMLKERQPGISMANSSALPSSSAGISKELIDLQPLIQFPEEVASILM
EQEQNIYRRVLPVDYLCFLTRDLGTPECQTSLPCLKASISASILTSQNREHNALEDLVMR
FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYRKVITRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQIIRSCSRS
LEAEDEDSASEGNSSRKNSLRDKARWQFIIGDLLDSENDLCEQSKEWDSHGSEEPQKAFD
HGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTAS
PASAKAKLGVLSNTAEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQN
KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSTEKPSVQRNNTLG
ISTTKKKKKILIRGESGEAADDEMATRKAKMHRESRSRSGSDPQDMNEQEESEANAIMSL
PNTLPSRRAHSLTTAGSPNLSAGTSSPIRPVSSPVLSSSNKSPSSPWSSSSWHGRIKGGM
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRAGSESAPLYTNLTI
DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLG
IFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNF
ASKNDESQENIKDLQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI
FKTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN
EEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGL
STLNASGSSRGKERKSRKSIFGNNPGRMSPGETAAFNKASGKSSYEGMRQAWEESSSPLN
PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPN
PLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE
RDLDNMEPAIYSLTIVSGQNVCPSSSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW
NEQFLFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS
LFINSRRMEENSSSSAVPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQ
LLQQILTTEQDTKPIVTDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIMQILSSWFPE
EGYVGRIVLKTQQENLEERSILQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVST
AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDATKKSSTPKSSQRVLLDQECVFQA
QSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPSQVLASEGV
QSKEEKLVGSLPSSDTTDYRQ
NT seq 6906 nt NT seq  +upstreamnt  +downstreamnt
atgacatctgaagaaatggcagcttctgttctcacacctgtgactcagagaagagtgacg
tccactccatcagctatagatgaaagtagtgaaaaggtcttggatgtcagtgttcctaaa
gcacatagtgtcaggcagagcaggcagacttctaccatcccacagatgaacaagctcaaa
gaagaaccttctggaagcaacttgcccaagattctctccatagcaagggagaaaacagtg
agcaatgagaacagcagtgaaaagtgctgggcagaaagtacaccagtttctgtgaaaaac
cttaacattaaccacaacaacatactgacaaaccaccagtgtgtccttcctcagagccag
tgttatgacacgtgtgattctgtcatggaggaagacccatgttcggaaactggaatcccg
tcctcactggaaagaaaggcattccctggaattcaactggaaatcgatggacctcccatg
gacattagtccctcaggaagtcagttggccattgtagagactggccaggcacaccctgat
ggcaacacagcagcatttcactttcattatggagttgacaaaacagtgtcagatgctgtc
tgtaccctgtcaggcaacttgattttggatgattgtggaaactgtgtgcaactacctggt
gttggtggggagcaaaagaaaaattatgtggcgtatacttgtaaactcatggaattggcc
gaaaactgtgataataagaatgggcagctgcagtgtgatcattgtgacaccttggatgac
aaatacttgtgcttggaaggttcttgccaaagggccagtgtggtatgttcaagtgacagc
ttttgcagggaggacttgactaacagtccacctgccaagacctttctgagccattttgag
gacttccctgacaattgtgaagatgtagaggaagatttttttaaaagcaaaaaggagagg
tccactttgttagttaggagattttgtaaaaatgacagggaagtaaagaaatctgtgtat
actgggacaagggcgatcgtgaggactctgccttctggtcacattgggctgggagcttat
agttatatcgatcagaagagaagtggtcccttgttgccctgtgggagagttctggaacgg
ctgtcagtggtggcgattaggcaggatgggagccagtgcctatcagaagcccagtggtat
cagatctacaatgcagtgcgaaggggagaagaaatagaaaatacaattggatctcgtctc
catgtcttcacaaagctcccagcctccgagacaacccatgaaaggattagcgttggtcct
tgcttaaagcagtgtgtccgagacaccatatgtgagtaccgtgccaccctgcagaggaca
tccatatctcagtacatcacgggttctctcctagaagcaaccacgtctttgggagcaaga
agtggcctactcaatacttttggaggctctactggacgaatgatgctgaaagaacgccaa
ccaggcatctccatggccaattccagtgccctcccttcaagttcagctgggatcagcaag
gagctgattgacctgcagcccctcattcagttcccagaggaagtcgccagcattctgatg
gagcaggaacagaacatttaccgaagggtcctgccagttgactacctttgcttcttgacc
cgggacttgggcactccggaatgccagacgtccctgccctgcctcaaagcatccatctca
gcttcaattcttacctcccagaacagagagcacaatgccctggaagatctggtgatgaga
tttaatgaggtgagctcctgggtgacgtggttgatcctcacggcgggctccatggaggag
aagcgagaagtcttctcctatttggtgcacgtggccaaatgctgctggaacatgggcaac
tacaatgctgtcatggagttcttggctggcctcaggtcaagaaaagttttgaaaatgtgg
cagtttatggaccagtctgacctggagaccatgaggagcctgaaggatgccatggctcag
cacgaatcttcctgcgagtacaggaaggtgatcacgcgggccctgcacatacccggctgt
aaggtggtcccattctgtggggtgtttctgaaggagctctgtgaagtactggacggagcc
tctggcctcatgaagctttgcccgaggtacaattctcaagaagaaactctagagtttgta
gccgattacagtggacaagataatttcttacaacgagtgggacataatggcttgaagaat
tcagagaaggagtccaccgtcaacagcatctttcagatcatcaggagctgcagccgaagt
ctggaggccgaggacgaggacagcgccagtgagggcaacagctctaggaaaaattcctta
agggataaagcgcggtggcagtttataattggagatttgctggattccgaaaatgacctc
tgtgagcagtcgaaagaatgggactctcatggatcagaagagccacagaaggcctttgac
cacgggacagagctgatcccgtggtacgtgctgtccatccgagctgatgtgcaccagttc
ctgctgcagggggccactgtcatccactacgaccaggacacgcacctgtcggcccgctgc
ttcctccagctccagcctgacaacagcaccttgacctgggtaaagcccaccactgcctcc
ccagccagtgctaaagcaaaacttggtgtgcttagtaacacggctgagcctggcaaattc
ccgttactgggcaatgctggattaagtggcctggcggagggggtcttggatctgttttca
gcaaaggctgtgtacatgggacaccctagcatcgatatacacactgtgtgtgttcagaac
aaactgggtagcatgtttctctcagagactggtgtgacactgctctatgggctgcagacc
acggacaataggttattgcactttgtggcacccaagcacaccgctaagatgctcttcagt
ggattgctagaactcacgagggccgtgaggaagatgaggaagttccctgaccagagacag
cagtggctgcggaaacagtacgtcagcctctatcaggaggatggacggtacgaaggccca
actttggctcacgccgtggagctgtttggtggccggcgatggagtacacgcaaccccagc
cctgggacatccgcgaagagtactgagaagcccagtgtgcagagaaacaacaccttgggc
ataagcaccaccaagaaaaagaagaaaatccttataaggggtgagagtggagaggcggct
gacgacgagatggccacgcggaaggccaaaatgcacagggagagtcgcagccggagtggt
tccgaccctcaagacatgaatgagcaagaagaatccgaggcgaatgccatcatgagcctt
cctaacactctgccttccagaagagcccactctttgaccacggctgggtcccctaacttg
tctgctgggacatcatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaac
aagagcccgtccagtccttggagcagcagcagctggcacgggaggatcaaaggaggaatg
aagggttttcagagcttcatggtttcagacagtaacatgagttttgttgaatttgttgag
ctgttcaaatcattcagcgtgaggagccgcaaggacctgaaggatctcttcgacgtctac
gccgtgccctgcaaccgagccggctccgagtcagcccccctctacaccaacctaaccatt
gacgaaaacaccagcgaccttcagcctgacctagatttattgaccagaaatgtctcagac
ttggggttgttcattaagagtaaacagcagctgtcagacaaccagaggcagatatctgat
gccattgctgctgcaagtatcgtgacaaatggcactggggtcgagagcacatctctgggc
atctttggggttggcatactccagctcaatgacttcctcgtcaactgccagggagagcac
tgcacttatgatgaaatcctcagcatcatccagaagttcgagcctagcgttagtatgtgt
catcagggcctactgtcatttgagggatttgcaaggtttctgatggataaagataatttt
gcctccaaaaatgacgagtcgcaggaaaacattaaagacttgcagctgcccctctcctac
tattacattgaatcttcacacaatacctacctcacagggcaccagctcaaaggagagtcc
tcagtggaactctacagccaggtcctcctgcaaggctgcagaagcgtagagttggactgc
tgggacggagatgatgggatgcccattatctaccacggacacacactgacaaccaagatc
cccttcaaggaggtggttgaagccattgaccgcagtgccttcatcaactctgacctgccc
atcatcatatcaattgagaaccactgctcattgcctcagcaacgaaaaatggcagaaatt
ttcaagactgtgtttggagaaaaactggtggctaaattcctgtttgagagcgatttctca
gatgatccaatgcttccctcacctgaccaacttaggaggaaagtgcttcttaaaaataag
aagctcaaagcccaccagacaccagtggatatcttaaagcaaaaggctcatcagttagca
tccatgcaagctcaggcttataatggggggaatgccaaccccccacctgccaataacgag
gaagaggaggatgaagaagacgaatatgattatgactatgaatccctgtctgatgacaat
attctagaagacagacctgaaaataaatcatgtaatgacaagcttcagttcgagtataat
gaagaaatccccaagaggataaagaaagccgataactctgcttgcaacaaaggaaaggtt
tatgacatggaactgggagaagaattttatcttcctcagaataaaaaggaaagtagacag
attgcaccagagctttctgaccttgtcatctattgccaagcggtaaaatttccaggcctg
tcaactctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatt
tttggcaacaatccgggcagaatgagccctggggagacagcagcgtttaacaaagcatct
ggaaaaagttcctatgaaggaatgcgacaggcctgggaggaatcttcttcccccctcaac
ccaaccacatccctcagcgctatcattagaactcccaaatgttaccatatttcatcgctg
aatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacacc
gcctgtcagctgctgaggacttacccggctgccacccgcatcgactcctccaaccccaat
cccctcatgttctggctccatgggatacagctcgtggcgctcaactaccagacagatgat
ctccccttacatttaaatgctgccatgtttgaggccaacggtggctgtggttatgttctg
aaacccccagttctgtgggacaagaactgtcccatgtatcagaagttttcacccttggaa
agagacctggacaacatggagcctgccatctattccttaactattgtctctggtcaaaac
gtgtgtccgagcagcagcacggggagcccgtgtatcgaagtcgacgtgctgggcatgccc
ttggacagctgccacttccgcacaaagcccatccaccggaacactctgaaccccatgtgg
aatgaacagtttctcttccgggtgcactttgaagacctcatatttcttcgttttgcagtc
gtggaaaacaacagctcagccgtaaccgctcagagaatcatcccgctcaaggctttgaaa
cgaggatatcggcatcttcagctacgaaacctccacaatgaagtcttggaaatctccagt
ttattcataaacagcagaaggatggaagaaaattcctccagcagtgccgtgccggcctct
ttgatgtttaatacagaagaaagaaaatgtttgcagactcacagagttacagtgcatggg
gtcccaggtccagagccgtttactgttttctccataaacgggggcaccaaggcaaagcag
cttctccaacaaattctgactactgaacaggacaccaaacctattgtcacagactatttt
ttgatggaagaaaaatattttatatctaaagaaaagaatgaatgcaggaaacaaccattc
cagagagtcatcggtccagaagaagagatcatgcagattttaagcagctggtttcccgag
gaaggatatgttggcaggattgtcttaaaaacccagcaggaaaacctagaagagagaagc
attcttcaagatgacaaagaggtgatcttgagctcagaggaggagagtttctttgttcaa
gttcacgacgtttctccagagcaacctcgaacagtcatcaaagcgccccgtgtcagcacc
gcgcaggacgtcattcagcagaccttatgcaaagccaaatattcctatagcatcctgagc
aaccccaacccgagtgactatgtgcttctggaggaggtggtgaaagatgctaccaagaag
tcttccaccccgaagtcctcccagcgagtccttttggatcaggagtgtgtgtttcaagcc
caaagcaagtggaagggcgcaggaaaattcatccttaagctaaaggagcaggtacaggca
tcccgagaagacaaaaggaaaggcatttcttttgcaagtgaattcaagaagttcactaag
tcaactaaacagccccgaggactcacgtcaccttctcaggtcttggcctcagaaggtgtc
caaagcaaggaggagaaactggtgggcagcttgccttccagtgacaccacagactaccga
caataa
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