KEGG   Ailuropoda melanoleuca (giant panda): 100479318Help
Entry
100479318         CDS       T01329                                 

Gene name
PLCE1
Definition
phospholipase C, epsilon 1
Orthology
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Phosphatidylinositol signaling system
Thyroid hormone signaling pathway
Proteoglycans in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:aml00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100479318 (PLCE1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100479318 (PLCE1)
   04015 Rap1 signaling pathway
    100479318 (PLCE1)
   04020 Calcium signaling pathway
    100479318 (PLCE1)
   04070 Phosphatidylinositol signaling system
    100479318 (PLCE1)
   04024 cAMP signaling pathway
    100479318 (PLCE1)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100479318 (PLCE1)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    100479318 (PLCE1)
Enzymes [BR:aml01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100479318 (PLCE1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
Un
AA seq 2301 aa AA seqDB search
MTSEEMAASVLTPVTQRRVTSTPSAIDESSEKVLDVSVPKAHSVRQSRQTSTIPQMNKLK
EEPSGSNLPKILSIAREKTVSNENSSEKCWAESTPVSVKNLNINHNNILTNHQCVLPQSQ
CYDTCDSVMEEDPCSETGIPSSLERKAFPGIQLEIDGPPMDISPSGSQLAIVETGQAHPD
GNTAAFHFHYGVDKTVSDAVCTLSGNLILDDCGNCVQLPGVGGEQKKNYVAYTCKLMELA
ENCDNKNGQLQCDHCDTLDDKYLCLEGSCQRASVVCSSDSFCREDLTNSPPAKTFLSHFE
DFPDNCEDVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLGAY
SYIDQKRSGPLLPCGRVLERLSVVAIRQDGSQCLSEAQWYQIYNAVRRGEEIENTIGSRL
HVFTKLPASETTHERISVGPCLKQCVRDTICEYRATLQRTSISQYITGSLLEATTSLGAR
SGLLNTFGGSTGRMMLKERQPGISMANSSALPSSSAGISKELIDLQPLIQFPEEVASILM
EQEQNIYRRVLPVDYLCFLTRDLGTPECQTSLPCLKASISASILTSQNREHNALEDLVMR
FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYRKVITRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQIIRSCSRS
LEAEDEDSASEGNSSRKNSLRDKARWQFIIGDLLDSENDLCEQSKEWDSHGSEEPQKAFD
HGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTAS
PASAKAKLGVLSNTAEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQN
KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSTEKPSVQRNNTLG
ISTTKKKKKILIRGESGEAADDEMATRKAKMHRESRSRSGSDPQDMNEQEESEANAIMSL
PNTLPSRRAHSLTTAGSPNLSAGTSSPIRPVSSPVLSSSNKSPSSPWSSSSWHGRIKGGM
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRAGSESAPLYTNLTI
DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLG
IFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNF
ASKNDESQENIKDLQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI
FKTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN
EEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGL
STLNASGSSRGKERKSRKSIFGNNPGRMSPGETAAFNKASGKSSYEGMRQAWEESSSPLN
PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPN
PLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE
RDLDNMEPAIYSLTIVSGQNVCPSSSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW
NEQFLFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS
LFINSRRMEENSSSSAVPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQ
LLQQILTTEQDTKPIVTDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIMQILSSWFPE
EGYVGRIVLKTQQENLEERSILQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVST
AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDATKKSSTPKSSQRVLLDQECVFQA
QSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPSQVLASEGV
QSKEEKLVGSLPSSDTTDYRQ
NT seq 6906 nt NT seq  +upstreamnt  +downstreamnt
atgacatctgaagaaatggcagcttctgttctcacacctgtgactcagagaagagtgacg
tccactccatcagctatagatgaaagtagtgaaaaggtcttggatgtcagtgttcctaaa
gcacatagtgtcaggcagagcaggcagacttctaccatcccacagatgaacaagctcaaa
gaagaaccttctggaagcaacttgcccaagattctctccatagcaagggagaaaacagtg
agcaatgagaacagcagtgaaaagtgctgggcagaaagtacaccagtttctgtgaaaaac
cttaacattaaccacaacaacatactgacaaaccaccagtgtgtccttcctcagagccag
tgttatgacacgtgtgattctgtcatggaggaagacccatgttcggaaactggaatcccg
tcctcactggaaagaaaggcattccctggaattcaactggaaatcgatggacctcccatg
gacattagtccctcaggaagtcagttggccattgtagagactggccaggcacaccctgat
ggcaacacagcagcatttcactttcattatggagttgacaaaacagtgtcagatgctgtc
tgtaccctgtcaggcaacttgattttggatgattgtggaaactgtgtgcaactacctggt
gttggtggggagcaaaagaaaaattatgtggcgtatacttgtaaactcatggaattggcc
gaaaactgtgataataagaatgggcagctgcagtgtgatcattgtgacaccttggatgac
aaatacttgtgcttggaaggttcttgccaaagggccagtgtggtatgttcaagtgacagc
ttttgcagggaggacttgactaacagtccacctgccaagacctttctgagccattttgag
gacttccctgacaattgtgaagatgtagaggaagatttttttaaaagcaaaaaggagagg
tccactttgttagttaggagattttgtaaaaatgacagggaagtaaagaaatctgtgtat
actgggacaagggcgatcgtgaggactctgccttctggtcacattgggctgggagcttat
agttatatcgatcagaagagaagtggtcccttgttgccctgtgggagagttctggaacgg
ctgtcagtggtggcgattaggcaggatgggagccagtgcctatcagaagcccagtggtat
cagatctacaatgcagtgcgaaggggagaagaaatagaaaatacaattggatctcgtctc
catgtcttcacaaagctcccagcctccgagacaacccatgaaaggattagcgttggtcct
tgcttaaagcagtgtgtccgagacaccatatgtgagtaccgtgccaccctgcagaggaca
tccatatctcagtacatcacgggttctctcctagaagcaaccacgtctttgggagcaaga
agtggcctactcaatacttttggaggctctactggacgaatgatgctgaaagaacgccaa
ccaggcatctccatggccaattccagtgccctcccttcaagttcagctgggatcagcaag
gagctgattgacctgcagcccctcattcagttcccagaggaagtcgccagcattctgatg
gagcaggaacagaacatttaccgaagggtcctgccagttgactacctttgcttcttgacc
cgggacttgggcactccggaatgccagacgtccctgccctgcctcaaagcatccatctca
gcttcaattcttacctcccagaacagagagcacaatgccctggaagatctggtgatgaga
tttaatgaggtgagctcctgggtgacgtggttgatcctcacggcgggctccatggaggag
aagcgagaagtcttctcctatttggtgcacgtggccaaatgctgctggaacatgggcaac
tacaatgctgtcatggagttcttggctggcctcaggtcaagaaaagttttgaaaatgtgg
cagtttatggaccagtctgacctggagaccatgaggagcctgaaggatgccatggctcag
cacgaatcttcctgcgagtacaggaaggtgatcacgcgggccctgcacatacccggctgt
aaggtggtcccattctgtggggtgtttctgaaggagctctgtgaagtactggacggagcc
tctggcctcatgaagctttgcccgaggtacaattctcaagaagaaactctagagtttgta
gccgattacagtggacaagataatttcttacaacgagtgggacataatggcttgaagaat
tcagagaaggagtccaccgtcaacagcatctttcagatcatcaggagctgcagccgaagt
ctggaggccgaggacgaggacagcgccagtgagggcaacagctctaggaaaaattcctta
agggataaagcgcggtggcagtttataattggagatttgctggattccgaaaatgacctc
tgtgagcagtcgaaagaatgggactctcatggatcagaagagccacagaaggcctttgac
cacgggacagagctgatcccgtggtacgtgctgtccatccgagctgatgtgcaccagttc
ctgctgcagggggccactgtcatccactacgaccaggacacgcacctgtcggcccgctgc
ttcctccagctccagcctgacaacagcaccttgacctgggtaaagcccaccactgcctcc
ccagccagtgctaaagcaaaacttggtgtgcttagtaacacggctgagcctggcaaattc
ccgttactgggcaatgctggattaagtggcctggcggagggggtcttggatctgttttca
gcaaaggctgtgtacatgggacaccctagcatcgatatacacactgtgtgtgttcagaac
aaactgggtagcatgtttctctcagagactggtgtgacactgctctatgggctgcagacc
acggacaataggttattgcactttgtggcacccaagcacaccgctaagatgctcttcagt
ggattgctagaactcacgagggccgtgaggaagatgaggaagttccctgaccagagacag
cagtggctgcggaaacagtacgtcagcctctatcaggaggatggacggtacgaaggccca
actttggctcacgccgtggagctgtttggtggccggcgatggagtacacgcaaccccagc
cctgggacatccgcgaagagtactgagaagcccagtgtgcagagaaacaacaccttgggc
ataagcaccaccaagaaaaagaagaaaatccttataaggggtgagagtggagaggcggct
gacgacgagatggccacgcggaaggccaaaatgcacagggagagtcgcagccggagtggt
tccgaccctcaagacatgaatgagcaagaagaatccgaggcgaatgccatcatgagcctt
cctaacactctgccttccagaagagcccactctttgaccacggctgggtcccctaacttg
tctgctgggacatcatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaac
aagagcccgtccagtccttggagcagcagcagctggcacgggaggatcaaaggaggaatg
aagggttttcagagcttcatggtttcagacagtaacatgagttttgttgaatttgttgag
ctgttcaaatcattcagcgtgaggagccgcaaggacctgaaggatctcttcgacgtctac
gccgtgccctgcaaccgagccggctccgagtcagcccccctctacaccaacctaaccatt
gacgaaaacaccagcgaccttcagcctgacctagatttattgaccagaaatgtctcagac
ttggggttgttcattaagagtaaacagcagctgtcagacaaccagaggcagatatctgat
gccattgctgctgcaagtatcgtgacaaatggcactggggtcgagagcacatctctgggc
atctttggggttggcatactccagctcaatgacttcctcgtcaactgccagggagagcac
tgcacttatgatgaaatcctcagcatcatccagaagttcgagcctagcgttagtatgtgt
catcagggcctactgtcatttgagggatttgcaaggtttctgatggataaagataatttt
gcctccaaaaatgacgagtcgcaggaaaacattaaagacttgcagctgcccctctcctac
tattacattgaatcttcacacaatacctacctcacagggcaccagctcaaaggagagtcc
tcagtggaactctacagccaggtcctcctgcaaggctgcagaagcgtagagttggactgc
tgggacggagatgatgggatgcccattatctaccacggacacacactgacaaccaagatc
cccttcaaggaggtggttgaagccattgaccgcagtgccttcatcaactctgacctgccc
atcatcatatcaattgagaaccactgctcattgcctcagcaacgaaaaatggcagaaatt
ttcaagactgtgtttggagaaaaactggtggctaaattcctgtttgagagcgatttctca
gatgatccaatgcttccctcacctgaccaacttaggaggaaagtgcttcttaaaaataag
aagctcaaagcccaccagacaccagtggatatcttaaagcaaaaggctcatcagttagca
tccatgcaagctcaggcttataatggggggaatgccaaccccccacctgccaataacgag
gaagaggaggatgaagaagacgaatatgattatgactatgaatccctgtctgatgacaat
attctagaagacagacctgaaaataaatcatgtaatgacaagcttcagttcgagtataat
gaagaaatccccaagaggataaagaaagccgataactctgcttgcaacaaaggaaaggtt
tatgacatggaactgggagaagaattttatcttcctcagaataaaaaggaaagtagacag
attgcaccagagctttctgaccttgtcatctattgccaagcggtaaaatttccaggcctg
tcaactctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatt
tttggcaacaatccgggcagaatgagccctggggagacagcagcgtttaacaaagcatct
ggaaaaagttcctatgaaggaatgcgacaggcctgggaggaatcttcttcccccctcaac
ccaaccacatccctcagcgctatcattagaactcccaaatgttaccatatttcatcgctg
aatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacacc
gcctgtcagctgctgaggacttacccggctgccacccgcatcgactcctccaaccccaat
cccctcatgttctggctccatgggatacagctcgtggcgctcaactaccagacagatgat
ctccccttacatttaaatgctgccatgtttgaggccaacggtggctgtggttatgttctg
aaacccccagttctgtgggacaagaactgtcccatgtatcagaagttttcacccttggaa
agagacctggacaacatggagcctgccatctattccttaactattgtctctggtcaaaac
gtgtgtccgagcagcagcacggggagcccgtgtatcgaagtcgacgtgctgggcatgccc
ttggacagctgccacttccgcacaaagcccatccaccggaacactctgaaccccatgtgg
aatgaacagtttctcttccgggtgcactttgaagacctcatatttcttcgttttgcagtc
gtggaaaacaacagctcagccgtaaccgctcagagaatcatcccgctcaaggctttgaaa
cgaggatatcggcatcttcagctacgaaacctccacaatgaagtcttggaaatctccagt
ttattcataaacagcagaaggatggaagaaaattcctccagcagtgccgtgccggcctct
ttgatgtttaatacagaagaaagaaaatgtttgcagactcacagagttacagtgcatggg
gtcccaggtccagagccgtttactgttttctccataaacgggggcaccaaggcaaagcag
cttctccaacaaattctgactactgaacaggacaccaaacctattgtcacagactatttt
ttgatggaagaaaaatattttatatctaaagaaaagaatgaatgcaggaaacaaccattc
cagagagtcatcggtccagaagaagagatcatgcagattttaagcagctggtttcccgag
gaaggatatgttggcaggattgtcttaaaaacccagcaggaaaacctagaagagagaagc
attcttcaagatgacaaagaggtgatcttgagctcagaggaggagagtttctttgttcaa
gttcacgacgtttctccagagcaacctcgaacagtcatcaaagcgccccgtgtcagcacc
gcgcaggacgtcattcagcagaccttatgcaaagccaaatattcctatagcatcctgagc
aaccccaacccgagtgactatgtgcttctggaggaggtggtgaaagatgctaccaagaag
tcttccaccccgaagtcctcccagcgagtccttttggatcaggagtgtgtgtttcaagcc
caaagcaagtggaagggcgcaggaaaattcatccttaagctaaaggagcaggtacaggca
tcccgagaagacaaaaggaaaggcatttcttttgcaagtgaattcaagaagttcactaag
tcaactaaacagccccgaggactcacgtcaccttctcaggtcttggcctcagaaggtgtc
caaagcaaggaggagaaactggtgggcagcttgccttccagtgacaccacagactaccga
caataa

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