KEGG   Ailuropoda melanoleuca (giant panda): 100479580Help
Entry
100479580         CDS       T01329                                 

Gene name
PIK3CD
Definition
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
  KO
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100479580 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100479580 (PIK3CD)
   04015 Rap1 signaling pathway
    100479580 (PIK3CD)
   04012 ErbB signaling pathway
    100479580 (PIK3CD)
   04370 VEGF signaling pathway
    100479580 (PIK3CD)
   04630 Jak-STAT signaling pathway
    100479580 (PIK3CD)
   04668 TNF signaling pathway
    100479580 (PIK3CD)
   04066 HIF-1 signaling pathway
    100479580 (PIK3CD)
   04068 FoxO signaling pathway
    100479580 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    100479580 (PIK3CD)
   04071 Sphingolipid signaling pathway
    100479580 (PIK3CD)
   04024 cAMP signaling pathway
    100479580 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    100479580 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    100479580 (PIK3CD)
   04152 AMPK signaling pathway
    100479580 (PIK3CD)
   04150 mTOR signaling pathway
    100479580 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100479580 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    100479580 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    100479580 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    100479580 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100479580 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    100479580 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    100479580 (PIK3CD)
   04660 T cell receptor signaling pathway
    100479580 (PIK3CD)
   04662 B cell receptor signaling pathway
    100479580 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    100479580 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    100479580 (PIK3CD)
   04670 Leukocyte transendothelial migration
    100479580 (PIK3CD)
   04062 Chemokine signaling pathway
    100479580 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    100479580 (PIK3CD)
   04923 Regulation of lipolysis in adipocyte
    100479580 (PIK3CD)
   04915 Estrogen signaling pathway
    100479580 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    100479580 (PIK3CD)
   04917 Prolactin signaling pathway
    100479580 (PIK3CD)
   04921 Oxytocin signaling pathway
    100479580 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    100479580 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100479580 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100479580 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100479580 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    100479580 (PIK3CD)
   04722 Neurotrophin signaling pathway
    100479580 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100479580 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    100479580 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100479580 (PIK3CD)
   05230 Central carbon metabolism in cancer
    100479580 (PIK3CD)
   05231 Choline metabolism in cancer
    100479580 (PIK3CD)
   05205 Proteoglycans in cancer
    100479580 (PIK3CD)
   05203 Viral carcinogenesis
    100479580 (PIK3CD)
   05210 Colorectal cancer
    100479580 (PIK3CD)
   05212 Pancreatic cancer
    100479580 (PIK3CD)
   05214 Glioma
    100479580 (PIK3CD)
   05221 Acute myeloid leukemia
    100479580 (PIK3CD)
   05220 Chronic myeloid leukemia
    100479580 (PIK3CD)
   05218 Melanoma
    100479580 (PIK3CD)
   05211 Renal cell carcinoma
    100479580 (PIK3CD)
   05215 Prostate cancer
    100479580 (PIK3CD)
   05213 Endometrial cancer
    100479580 (PIK3CD)
   05222 Small cell lung cancer
    100479580 (PIK3CD)
   05223 Non-small cell lung cancer
    100479580 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100479580 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100479580 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100479580 (PIK3CD)
   05166 HTLV-I infection
    100479580 (PIK3CD)
   05162 Measles
    100479580 (PIK3CD)
   05164 Influenza A
    100479580 (PIK3CD)
   05161 Hepatitis B
    100479580 (PIK3CD)
   05160 Hepatitis C
    100479580 (PIK3CD)
   05169 Epstein-Barr virus infection
    100479580 (PIK3CD)
   05146 Amoebiasis
    100479580 (PIK3CD)
   05145 Toxoplasmosis
    100479580 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    100479580 (PIK3CD)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100479580 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
Un
AA seq 1039 aa AA seqDB search
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRQEYLYGGYPLCQFQYICGCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEVSWGPWAAGRPAGHSSTRHEVQERFPEALARLL
LVTKWNKHEDVAGAGSPQMLYLLGSWPELPVLSALELLDCSFPDRHVGSFAIKSLRKLTD
DELFRYLLQLVQVLKYESYLDCELAKFLLARALANRKIGHFLFWHLRSEMHVPSVALRFG
LIMEAYCRGSTHHMKVLVKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHVCMRQETYL
EALSNVQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLR
QDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMA
ATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYT
ILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRE
SWKTKVNWLAHNVSKDNRQ
NT seq 3120 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggttgactgccccatggaattctggaccaaggaggagaatcagagtgtg
gccgttgacttcctgttgcccacgggggtctatctgaacttccctgtgtcccggaatgcc
aacctcagcaccatcaagaaggtgttgtggcaccgggcccagtatgagccactcttccac
atgctcagcgaccccgaggcctatgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctctgcgacatccagcccttcctgccagtgctgcgg
ctcgtggcccgagagggcgacagggtgaagaagctggtcaactctcagatcagcctcctc
atcggcaaaggcctccacgagttcgactccctgcatgacccagaagtgaatgccttccgc
accaagatgcgccagttctgtgaggaggcggccgcccggcggcagcagctgggctgggag
gcctggctacagtacagcttcccgctgcagctggagccctcggcgcggagctggggggcc
ggcaccctgagggtccccaaccgggccctcctggtcaacgtcaagttcgagggcagtgag
gagagcttcaccttccaggtgtccaccaaggacgtgccgctggcgctgatggcgtgcgcg
ctgcggaagaaggccaccgtgttccggcagcccctggtggagcagcccgaggactacaca
ctgcaggtgaacgggaggcaggagtacctgtacggcggctacccgctctgccagttccag
tacatctgcggctgcctgcacagcggcctgaccccccacctgaccatggtgcactcgtcc
tccatcctcgccatgcgggacgagcagagcgaccctgccccccaagtccagaaaccgcgc
accaaaccaccccccattcccatgaagaagccttcctccttgtccctgtggtccctggag
cagcctttctgcgtggagctgattcagggcagcaaagtgaatgccgatgagcggatgaag
ctggtcgtgcaggcggggctgttccacggcaacgagacgctgtgcaagacagtgtccagc
tcggaggtgagcgtgtgctcagagcccgtatggaaacagcggctggagtttgacatcaac
atctgtgacctgccccgcatggcccgtctctgctttgcactttacgccgtgatcgagaag
gccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgccccatcgcttgg
gccaacctcatgctgtttgactacaaggaccagctcaagaccggtgaatgctgcctgtac
atgtggccgtccgtcccagacgagaaaggggagctgctgaaccccacggggacagtgagg
agtaaccccaacacggagagcgctgcggccctcgtcatctgcctccccgaggtggccccc
taccctgtgtactaccccaccctggacaagattctggagctggggcggcacggggagcac
gggcgcttcagcgaggaagaggtgagctgggggccgtgggcggcggggcgcccggctggc
cacagctccacccggcacgaggtccaggagcgcttccccgaggcgctggcccgcctgctg
ctggtcaccaagtggaacaagcacgaggacgtggctggtgctggctccccccagatgctc
tacctgctgggctcctggcccgagctgcccgtcctgagcgccctggagctgctggactgc
agcttccccgaccgccacgtgggctccttcgccatcaagtctctgcggaagttgacggac
gacgagctcttccggtacctgctgcagctggtgcaggtgctcaagtacgagtcctacctc
gactgcgagctggccaagttcctgctggcgcgggccctggccaaccgcaagatcggccac
ttcctcttctggcacctccgctccgagatgcacgtgccgtccgtggctctgcgcttcggc
ctcatcatggaggcctactgccggggcagcacccaccacatgaaggtgctcgtgaagcag
ggggaggcgctgagcaaactgaaggccctgaatgacttcgtcaaagtgagctcccagaag
accaccaagccccagaccaaggagctgatgcacgtgtgcatgcgtcaggagacctacctg
gaggccctctccaacgtgcagtccccgctggaccccagcaccctgctggctgaagtctgc
gtggagcagtgcaccttcatggactccaagatgaagcccttgtgggtcatgtacagcaac
gaggaggcaggcagcgacggcagcgtgggcatcatctttaagaacggggacgacctccgc
caggacatgctgactctgcagatgatccagctcatggatgttctgtggaagcaggaggga
ctggacctgaggatgaccccctacggctgcctctccacgggggaccgcactggcctcatc
gaggtggtgcttcactcagacaccatcgccaacatccagttgaacaaaagcaacatggcg
gccacagctgccttcaacaaggatgccctgctcaactggctcaagtccaagaaccctggg
gaggccttggatcgagccatcgaggagtttaccctctcctgtgccggctactgtgtggcc
acttacgtgctgggcatcggagatcggcacagcgacaacatcatgatccgcgagaacggg
cagctcttccacattgatttcggccactttctgggcaacttcaagaccaagtttggaatc
aaccgtgagcgagtcccgttcatcctcacgtatgactttgtgcacgtgatccagcagggg
aaaacgaataacagtgagaaatttgaaaggttccggggttactgtgagcgagcctacact
atcctgaggcgccacgggctgctctttctccacctcttcgccctgatgcgggctgccggc
ctgcctgagctcagctgctccaaagacatccagtatctcaaggactctctggcgttggga
aagacggaggaggaggctctaaagcacttccgagtgaagttcaacgaagccctccgggag
agctggaaaaccaaagtgaactggctggcccacaatgtgtccaaagataacaggcaatag

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