KEGG   Ailuropoda melanoleuca (giant panda): 100479580Help
Entry
100479580         CDS       T01329                                 

Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:aml00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100479580
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100479580
   04015 Rap1 signaling pathway
    100479580
   04012 ErbB signaling pathway
    100479580
   04370 VEGF signaling pathway
    100479580
   04630 Jak-STAT signaling pathway
    100479580
   04668 TNF signaling pathway
    100479580
   04066 HIF-1 signaling pathway
    100479580
   04068 FoxO signaling pathway
    100479580
   04070 Phosphatidylinositol signaling system
    100479580
   04024 cAMP signaling pathway
    100479580
   04022 cGMP - PKG signaling pathway
    100479580
   04151 PI3K-Akt signaling pathway
    100479580
   04152 AMPK signaling pathway
    100479580
   04150 mTOR signaling pathway
    100479580
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100479580
  Cell growth and death
   04210 Apoptosis
    100479580
  Cell communication
   04510 Focal adhesion
    100479580
 Organismal Systems
  Immune system
   04611 Platelet activation
    100479580
   04620 Toll-like receptor signaling pathway
    100479580
   04650 Natural killer cell mediated cytotoxicity
    100479580
   04660 T cell receptor signaling pathway
    100479580
   04662 B cell receptor signaling pathway
    100479580
   04664 Fc epsilon RI signaling pathway
    100479580
   04666 Fc gamma R-mediated phagocytosis
    100479580
   04670 Leukocyte transendothelial migration
    100479580
   04062 Chemokine signaling pathway
    100479580
  Endocrine system
   04910 Insulin signaling pathway
    100479580
   04915 Estrogen signaling pathway
    100479580
   04914 Progesterone-mediated oocyte maturation
    100479580
   04917 Prolactin signaling pathway
    100479580
   04921 Oxytocin signaling pathway
    100479580
   04919 Thyroid hormone signaling pathway
    100479580
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100479580
  Digestive system
   04973 Carbohydrate digestion and absorption
    100479580
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100479580
  Nervous system
   04725 Cholinergic synapse
    100479580
   04722 Neurotrophin signaling pathway
    100479580
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100479580
  Development
   04380 Osteoclast differentiation
    100479580
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100479580
   05205 Proteoglycans in cancer
    100479580
   05203 Viral carcinogenesis
    100479580
   05210 Colorectal cancer
    100479580
   05212 Pancreatic cancer
    100479580
   05214 Glioma
    100479580
   05221 Acute myeloid leukemia
    100479580
   05220 Chronic myeloid leukemia
    100479580
   05218 Melanoma
    100479580
   05211 Renal cell carcinoma
    100479580
   05215 Prostate cancer
    100479580
   05213 Endometrial cancer
    100479580
   05222 Small cell lung cancer
    100479580
   05223 Non-small cell lung cancer
    100479580
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100479580
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100479580
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100479580
   05166 HTLV-I infection
    100479580
   05162 Measles
    100479580
   05164 Influenza A
    100479580
   05161 Hepatitis B
    100479580
   05160 Hepatitis C
    100479580
   05169 Epstein-Barr virus infection
    100479580
   05146 Amoebiasis
    100479580
   05145 Toxoplasmosis
    100479580
   05142 Chagas disease (American trypanosomiasis)
    100479580
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100479580
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1027 aa AA seqDB search
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRQEYLYGGYPLCQFQYICGCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEXXXXXRHEVQERFPEALARLLLVTKWNKHEDVA
GAGSPQMLYLLGSWPELPVLSALELLDCSFPDRHVGSFAIKSLRKLTDDELFRYLLQLVQ
VLKYESYLDCELAKFLLARALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTH
HMKVLVKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHVCMRQETYLEALSNVQSPLDP
STLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHL
FALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHN
VSKDNRQ
NT seq 3084 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggttgactgccccatggaattctggaccaaggaggagaatcagagtgtg
gccgttgacttcctgttgcccacgggggtctatctgaacttccctgtgtcccggaatgcc
aacctcagcaccatcaagaaggtgttgtggcaccgggcccagtatgagccactcttccac
atgctcagcgaccccgaggcctatgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctctgcgacatccagcccttcctgccagtgctgcgg
ctcgtggcccgagagggcgacagggtgaagaagctggtcaactctcagatcagcctcctc
atcggcaaaggcctccacgagttcgactccctgcatgacccagaagtgaatgccttccgc
accaagatgcgccagttctgtgaggaggcggccgcccggcggcagcagctgggctgggag
gcctggctacagtacagcttcccgctgcagctggagccctcggcgcggagctggggggcc
ggcaccctgagggtccccaaccgggccctcctggtcaacgtcaagttcgagggcagtgag
gagagcttcaccttccaggtgtccaccaaggacgtgccgctggcgctgatggcgtgcgcg
ctgcggaagaaggccaccgtgttccggcagcccctggtggagcagcccgaggactacaca
ctgcaggtgaacgggaggcaggagtacctgtacggcggctacccgctctgccagttccag
tacatctgcggctgcctgcacagcggcctgaccccccacctgaccatggtgcactcgtcc
tccatcctcgccatgcgggacgagcagagcgaccctgccccccaagtccagaaaccgcgc
accaaaccaccccccattcccatgaagaagccttcctccttgtccctgtggtccctggag
cagcctttctgcgtggagctgattcagggcagcaaagtgaatgccgatgagcggatgaag
ctggtcgtgcaggcggggctgttccacggcaacgagacgctgtgcaagacagtgtccagc
tcggaggtgagcgtgtgctcagagcccgtatggaaacagcggctggagtttgacatcaac
atctgtgacctgccccgcatggcccgtctctgctttgcactttacgccgtgatcgagaag
gccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgccccatcgcttgg
gccaacctcatgctgtttgactacaaggaccagctcaagaccggtgaatgctgcctgtac
atgtggccgtccgtcccagacgagaaaggggagctgctgaaccccacggggacagtgagg
agtaaccccaacacggagagcgctgcggccctcgtcatctgcctccccgaggtggccccc
taccctgtgtactaccccaccctggacaagattctggagctggggcggcacggggagcac
gggcgcttcagcgaggaagagnnnnnnnnnnnnnnncggcacgaggtccaggagcgcttc
cccgaggcgctggcccgcctgctgctggtcaccaagtggaacaagcacgaggacgtggct
ggtgctggctccccccagatgctctacctgctgggctcctggcccgagctgcccgtcctg
agcgccctggagctgctggactgcagcttccccgaccgccacgtgggctccttcgccatc
aagtctctgcggaagttgacggacgacgagctcttccggtacctgctgcagctggtgcag
gtgctcaagtacgagtcctacctcgactgcgagctggccaagttcctgctggcgcgggcc
ctggccaaccgcaagatcggccacttcctcttctggcacctccgctccgagatgcacgtg
ccgtccgtggctctgcgcttcggcctcatcatggaggcctactgccggggcagcacccac
cacatgaaggtgctcgtgaagcagggggaggcgctgagcaaactgaaggccctgaatgac
ttcgtcaaagtgagctcccagaagaccaccaagccccagaccaaggagctgatgcacgtg
tgcatgcgtcaggagacctacctggaggccctctccaacgtgcagtccccgctggacccc
agcaccctgctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaag
cccttgtgggtcatgtacagcaacgaggaggcaggcagcgacggcagcgtgggcatcatc
tttaagaacggggacgacctccgccaggacatgctgactctgcagatgatccagctcatg
gatgttctgtggaagcaggagggactggacctgaggatgaccccctacggctgcctctcc
acgggggaccgcactggcctcatcgaggtggtgcttcactcagacaccatcgccaacatc
cagttgaacaaaagcaacatggcggccacagctgccttcaacaaggatgccctgctcaac
tggctcaagtccaagaaccctggggaggccttggatcgagccatcgaggagtttaccctc
tcctgtgccggctactgtgtggccacttacgtgctgggcatcggagatcggcacagcgac
aacatcatgatccgcgagaacgggcagctcttccacattgatttcggccactttctgggc
aacttcaagaccaagtttggaatcaaccgtgagcgagtcccgttcatcctcacgtatgac
tttgtgcacgtgatccagcaggggaaaacgaataacagtgagaaatttgaaaggttccgg
ggttactgtgagcgagcctacactatcctgaggcgccacgggctgctctttctccacctc
ttcgccctgatgcgggctgccggcctgcctgagctcagctgctccaaagacatccagtat
ctcaaggactctctggcgttgggaaagacggaggaggaggctctaaagcacttccgagtg
aagttcaacgaagccctccgggagagctggaaaaccaaagtgaactggctggcccacaat
gtgtccaaagataacaggcaatag

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