KEGG   Ailuropoda melanoleuca (giant panda): 100479804
Entry
100479804         CDS       T01329                                 
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
  KO
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml00790  Folate biosynthesis
aml01100  Metabolic pathways
aml01240  Biosynthesis of cofactors
aml01523  Antifolate resistance
Brite
KEGG Orthology (KO) [BR:aml00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100479804 (FPGS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100479804 (FPGS)
Enzymes [BR:aml01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.17  tetrahydrofolate synthase
     100479804 (FPGS)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C
Other DBs
NCBI-GeneID: 100479804
NCBI-ProteinID: XP_002915221
Ensembl: ENSAMEG00000015069
Position
7:53055427..53070860
AA seq 588 aa
MSQARCHLRAALFLAAVSPRGATTGVTAWRGLSAWPAPQEPGMEYQDAVRTLNTLQTNAG
YLEQVKRQRGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPVSPELFTKHFWRLYHRLEETKDSSSCVSMPAYFR
FLTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGISSLGIDHTSLLGDTVEEI
AWQKGGIFKCGVPAFTVLQPDGPLAVLRDRAQHISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKGHQGLGELKVSRPSVLRQMPLAPVFQPTSHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTASSVQACVRWFRQALHRSHRPSHGPEVRVLLFNATGDR
DPAALLKLLQPCQFDYAVFCPNLTDVSSAGSADQQNFMVTLDQVLLRCLAHQRHWSHLAE
EQASPDPWSPASPEPGEPTSLLLASRPPRTHSTSSLVFSCISHALQWISQGRDPVFQPPN
PPQGLLAHPVAGSGAGVLQEAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq 1767 nt   +upstreamnt  +downstreamnt
atgtcgcaggcacgctgccacctgcgcgccgctctcttcctggcagcagtttctccgcgc
ggtgcaacgaccggggtcacggcgtggcgagggttgagcgcgtggcccgcgccgcaggag
ccgggcatggagtatcaggatgctgtgcgcacactgaacaccctgcagaccaatgctggc
tacctggagcaggtgaagcgccagcggggtgaccctcagacacagctggaagcgatgaag
ctgtatttggcccggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacttgtgccttcaccgaacgtattctccgcagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcagcccgtaagccccgagctcttcaccaagcacttctggcgcctctac
caccggctggaggagaccaaggacagcagcagctgcgtctccatgcccgcatacttccgc
ttcctcacgctcatggccttccacatcttcctccaagagaaggtggacctggcggtggta
gaagtgggcattggtggcgcttacgactgcaccaacatcatcaggaagcctgtggtgtgt
ggcatctcctctctcggcatcgaccacaccagccttctgggggacacagtggaagagatc
gcgtggcagaaagggggcatcttcaagtgtggcgtccctgctttcacggtgctccagccc
gacggtcccctggcagtgctgcgggaccgtgcccagcacatctcctgtcctctctacctg
tgcccgccactggaagccctggaggaaggggggccgccgctgaccctgggcctggaggga
gagcaccagcggtccaacgccgccttggccttgcagctggctcgctgctggctgcagcaa
aagggccaccagggcctcggggagctgaaggtgtctcggcccagcgtcttgcggcagatg
cccctggcacccgtgttccagcccacgtcccacatgcggcatgggcttcgggacacagag
tggctgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggacggcgcg
cataccgccagcagcgttcaggcctgcgtgcgttggttccgccaggcgctgcaccgcagc
cacaggccgagccacggccctgaggtgcgcgtcttgctcttcaatgccactggggaccgg
gatcccgcggccctgctgaagctgctgcagccctgtcagtttgactatgctgtcttctgc
cctaacctgacagacgtgtcgtctgctggcagcgcagaccagcagaacttcatggtgacc
ctggaccaggtgctgctccgctgccttgcgcaccagcggcactggagccacctggctgag
gagcaggccagcccggacccctggagccccgccagcccggagcctggtgagcccacatcc
ttgctgctggcttcccgcccaccccgcacccacagcaccagctccctcgtcttcagctgc
atctcccatgccctgcagtggatcagccaaggccgggaccccgtctttcagccacccaat
ccccctcagggcctccttgcccacccggtggcaggcagcggggccggcgtgctccaggag
gccgccgccatccacgtactggtcacgggcagcttgcacctggtgggcggcgtcctgaag
ctgctggagcctgccctgtcccagtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (2)   
   Pfam (2)   
All databases (51)   

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