KEGG   Ailuropoda melanoleuca (giant panda): 100480586Help
Entry
100480586         CDS       T01329                                 

Gene name
PLCG1
Definition
(RefSeq) phospholipase C, gamma 1
  KO
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Choline metabolism in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:aml00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100480586 (PLCG1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100480586 (PLCG1)
   04015 Rap1 signaling pathway
    100480586 (PLCG1)
   04012 ErbB signaling pathway
    100480586 (PLCG1)
   04370 VEGF signaling pathway
    100480586 (PLCG1)
   04064 NF-kappa B signaling pathway
    100480586 (PLCG1)
   04066 HIF-1 signaling pathway
    100480586 (PLCG1)
   04020 Calcium signaling pathway
    100480586 (PLCG1)
   04070 Phosphatidylinositol signaling system
    100480586 (PLCG1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100480586 (PLCG1)
   04660 T cell receptor signaling pathway
    100480586 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    100480586 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    100480586 (PLCG1)
   04670 Leukocyte transendothelial migration
    100480586 (PLCG1)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100480586 (PLCG1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100480586 (PLCG1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100480586 (PLCG1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100480586 (PLCG1)
   05231 Choline metabolism in cancer
    100480586 (PLCG1)
   05206 MicroRNAs in cancer
    100480586 (PLCG1)
   05205 Proteoglycans in cancer
    100480586 (PLCG1)
   05214 Glioma
    100480586 (PLCG1)
   05223 Non-small cell lung cancer
    100480586 (PLCG1)
  Infectious diseases
   05169 Epstein-Barr virus infection
    100480586 (PLCG1)
Enzymes [BR:aml01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100480586 (PLCG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
Un
AA seq 1261 aa AA seqDB search
MTLFYSKKSQRPERKTFQVXXXXXKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRD
FDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAAT
PLQIERWLRKQFYSLDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSSDIT
YGQFAQLYRSLMYSAQKTMDLPFLEASALRAGERPELCRVSLPEFQQFLLEYQGELWAVD
RLQVHEFMLSFLRDPLREIEEPYFSLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHY
WISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIK
FSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGL
PSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHY
FVLTSSKIYYSEETSSDQGNEDEEEPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLL
TEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGAPKFFLTDNLVF
DSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDG
AFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVTLGNSEFDSLVDLISYYEKHPLYRK
MKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDE
LTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVSPASLEPEREHLDENSPLG
DLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREV
AQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAE
KYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQM
NQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPYAICIEVLGARHLPKNGRGIVC
PFVEIEVAGAEYDSIKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSD
QNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLVKIDVFPAKQENGDLSPFSMSLR
ERGSDTSGQLFHGRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNR
L
NT seq 3786 nt NT seq  +upstreamnt  +downstreamnt
atgactttgttctactccaagaagtcgcagcggccggagcggaagaccttccaggtcaan
nnnnnnnnnnncaagctggagacgcggcagatcacgtggagccgtggcgccgacaagatc
gagggggccattgacattcgcgaaatcaaggagatccgcccagggaagacctcacgggat
tttgatcgctaccaagaggaccctgctttccgaccagaccagtcacactgctttgtcatc
ctgtatgggatggaattccgcctgaagaccctgagcctgcaagctacgtctgaggatgaa
gtgaacatgtggatcaagggtttaacatggttgatggaggatacattgcaggcagccacg
cctctgcagatcgagaggtggctgcggaagcagttctactcgctggatcggaatcgtgag
gatcgtatatcagccaaggacctgaagaacatgctgtcccaggtcaactaccgggtcccc
aacatgcgcttcctccgagagcgtctgacggacctggagcagcgcagcagtgacatcacc
tacgggcagtttgctcagctgtaccgcagcctgatgtacagcgcccagaagacgatggac
ctccccttcttggaagccagtgccctgagggctggggagcggccggagctctgtcgcgtg
tcccttcctgagttccagcagttcctcctcgagtaccagggggagctgtgggctgttgac
cggcttcaggtgcatgagttcatgctcagcttccttcgagaccccttgcgagaaattgaa
gagccatacttctccctggatgagtttgtcaccttcctgttctccaaagagaacagtgtg
tggaactcgcagctggatgcagtgtgcccggataccatgaacaaccctctctcccactac
tggatctcttcctcccacaacacgtacctgaccggggaccagttctccagcgagtcctcc
ctagaagcctacgctcgctgcctgcggatgggctgtcgctgcattgagttggactgctgg
gacggcccagatgggatgccagtcatttaccatggacacacccttaccaccaagatcaag
ttctcggatgttctgcacaccatcaaggagcatgcctttgtggcctcagagtacccggtc
atcctgtccatcgaggaccactgcagcattgctcagcagagaaacatggcacagtatttc
aagaaggtgcttggggacacactccttaccaagcccgtggacatcgctgccgacgggctc
ccctcacccaaccagctcaagaggaagatcctcatcaagcacaagaagctggcggagggc
agtgcctacgaagaggtgcctacgtcggtgatgtactccgagaatgatatcagcaactcc
atcaagaatggcatcctctacctggaggaccccgtgaaccatgagtggtacccccactat
ttcgttctgaccagcagcaagatctactactctgaggagaccagcagtgaccagggcaat
gaggatgaggaggagcccaaggaggccagtggcagcacagagctgcactccagtgagaag
tggttccatgggaagctcggggcgggacgggacggacggcacatcgctgagcgcctgctc
accgagtactgcatcgagaccggggcccctgatggctccttcctcgtgcgggagagcgag
acctttgtgggcgactacaccctctctttctggaggaacgggaaagtccagcactgccgg
atccactcccggcaggacgctggggcccccaagttcttcttgacagacaacttggtcttt
gactcgctctatgacctcatcacgcactaccagcaggtgcccctgcgctgcaacgaattt
gagatgcgcctctccgagcctgtcccgcagaccaatgcccacgagagcaaagagtggtac
cacgccagcctgaccagagctcaggccgagcacatgctgatgcgtgtcccccgggatggg
gccttcctggtgagaaaacggaatgagcccaactcctacgccatctccttccgggccgag
ggcaagatcaagcattgccgcgtccagcaggagggccagacggtgacgctgggcaactcg
gagttcgacagcctcgtggacctcatcagctactatgagaagcacccgctgtaccgcaag
atgaagctgcgctaccccatcaacgaggaggcgctagagaagatcggcaccgctgagcct
gactatggagccttgtatgagggacgcaaccctggcttctacgtagaggcaaatcctatg
ccgactttcaagtgtgcggtcaaagccctctttgactacaaggcccagagggaggacgag
ctgacgttcacaaagagcgccatcatccagaacgtggagaagcaagaaggcggctggtgg
cggggggactacggggggaagaagcagctgtggttcccgtcaaactacgtggaggagatg
gtcagccctgcatccctggagccggagagggagcacttggacgagaacagccccctgggg
gacttgctccggggggtcttggatgtgccggcttgtcagattgccatccgtcctgagggc
aagaacaaccggctcttcgtcttctccatcagcatggcttcagtggcgcactggtccttg
gacgtcgccgctgactcacaggaggagctgcaggactgggtgaagaagatccgagaagtg
gcccagacggcagacgccaggctcacagaggggaagatgatggagcgcagaaagaagatt
gccctagagctctccgagctggttgtctactgtcggcctgttcccttcgatgaagagaag
attggcacagaacgtgcctgctaccgggacatgtcgtcctttccggaaaccaaggctgag
aaatacgtgaacaaggccaaaggcaagaagttcctccagtacaaccgtctgcagctctcc
cgcatctaccccaagggccagcggctagactcctccaattacgaccccttgcccatgtgg
atctgcggcagtcagctggtggccctcaacttccagacgccagacaagcctatgcagatg
aaccaggcgctcttcatggccggtggccactgcggctacgtgctgcagcccagcaccatg
cgggatgaggcctttgacccttttgacaagagcagcctccgaggcctagagccatatgcc
atctgcattgaggtgctgggggcccggcacctgccaaagaatggccgaggcatcgtgtgt
ccttttgtggagattgaggtggccggagcggagtatgacagcatcaagcagaagacagag
tttgtggtggacaatggactgaaccctgtgtggcctgccaagcccttccacttccagatc
agtaacccggaatttgcctttctgcgctttgtggtgtatgaggaagacatgtttagtgac
cagaacttcttggctcaggctaccttcccggtgaaaggcctgaagacaggatacagagcc
gtgcctttgaagaacaactacagtgaggacttggagctggcctccctgctcgtcaagatc
gatgttttccctgccaagcaggaaaacggggacctcagtcccttcagtatgtctctgcgg
gagcggggctccgatacctcaggccagctgtttcatggccgggcccgggaaggttccttt
gaagcccgctaccagcagccatttgaggactttcgtatctcccaggagcacctggcagac
cattttgacagtcgggaacggagggccccacgaaggactcgggtcaacggagacaaccgc
ctctag

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