KEGG   Amycolatopsis mediterranei S699: AMES_5370
Entry
AMES_5370         CDS       T02190                                 
Symbol
fabF
Name
(GenBank) 3-oxoacyl-[acyl-carrier-protein] synthase II
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
amm  Amycolatopsis mediterranei S699
Pathway
amm01056  Biosynthesis of type II polyketide backbone
amm01100  Metabolic pathways
amm01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:amm00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    AMES_5370 (fabF)
   00253 Tetracycline biosynthesis
    AMES_5370 (fabF)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:amm01004]
    AMES_5370 (fabF)
   01008 Polyketide biosynthesis proteins [BR:amm01008]
    AMES_5370 (fabF)
Enzymes [BR:amm01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     AMES_5370 (fabF)
    2.3.1.260  tetracycline polyketide synthase
     AMES_5370 (fabF)
Lipid biosynthesis proteins [BR:amm01004]
 Polyketide synthase
  Component type
   AMES_5370 (fabF)
Polyketide biosynthesis proteins [BR:amm01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     AMES_5370 (fabF)
    Nonaketide PKS
     AMES_5370 (fabF)
    Decaketide PKS
     AMES_5370 (fabF)
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_N
Other DBs
NCBI-ProteinID: AFO78906
Position
complement(6037743..6039002)
AA seq 419 aa
MTRTAVITGIGVVAPGGIGTKAFWALLTEGRTATRPISAFDASRFRSRIAAECDFEGELN
GLTAEESGRLDRAAQFALVCADEAVVDGGLDPGALDPYRLGVTIGSAVGATIGLENEYLT
VSAGARDWVVDPAKAAPQLYEYLVPSSFAAEVAWRCGAQGPVATISTGCTSGLDAIGHAA
GLIESGEADVMLAGATDAPISPITVACFDAIKATSPDNDDAARASRPFDRTRNGFVLGEG
AAVFVVEEAESARRRGAHVYCAVSGFATRANAYHMTGLKPDGRELAEAIDVALRRASLPG
DRVGYVNAHGSGTKQNDRHETAAVKRSLGAHAYRVPVSSIKSMIGHSLGAIGSLEVAACA
LALEHQVVPPTANLHERDPECDLDYVPNVARETGLDTVLTVGSGFGGFQTAVVLTREPV
NT seq 1260 nt   +upstreamnt  +downstreamnt
gtgacgaggaccgcggtcatcaccggcatcggcgtcgtcgccccgggcggcatcggcacc
aaggccttctgggcgttgctcaccgaaggccgcaccgcgacccggccgatctcggccttc
gacgcctcccggttccgctcgcgcatcgcggccgagtgcgacttcgagggcgagctcaac
ggcctgaccgccgaggagtccgggcgcctcgaccgcgcggcgcagttcgcgctcgtctgc
gcggacgaagccgtggtcgacggcggcctggacccgggtgcgctcgacccgtaccggctc
ggcgtcacgatcggcagcgccgtcggcgccaccatcgggctggagaacgagtacctcacc
gtctccgcgggggcccgcgactgggtggtcgaccccgccaaggccgccccgcagctgtac
gagtacctcgtcccgagcagtttcgcggccgaagtcgcctggcgctgcggcgcacagggc
ccggtcgccacgatctccaccggctgcacctccgggctcgacgcgatcggccacgcggcc
gggctcatcgagtccggcgaggccgacgtcatgctcgccggcgccaccgacgcgccgatc
tcgccgatcaccgtcgcctgcttcgacgcgatcaaggccacgtcccccgacaacgacgac
gccgcgcgcgcgtcccgtccgttcgaccgcacgcgcaacggtttcgtgctcggcgaaggg
gccgccgtcttcgtcgtcgaggaagccgagagcgcccggcgacgcggcgcgcacgtctac
tgcgcggtctccggcttcgcgaccagggcgaacgcctaccacatgacggggctgaaaccc
gacggccgcgagctggccgaggccatcgacgtcgctctccgccgggccagcctgcccggc
gaccgcgtcggctacgtcaacgcccacggttcgggcaccaagcagaacgaccggcacgag
accgccgcggtcaaacgcagcctcggcgcgcacgcctaccgcgtgccggtcagctcgatc
aagtcgatgatcgggcactcgctcggcgcgatcggctcgctggaggtcgcggcctgcgcg
ctggcgctggagcaccaggtcgtgccgccgacggcgaacctgcacgagcgcgacccggaa
tgcgatctcgactacgtgccgaacgtcgcccgggaaaccgggctggacaccgtgctcacc
gtcggcagcggcttcggcgggttccagacggccgttgtcctgacccgggagccggtatga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (12)   
   KEGG ENZYME (2)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (45)   

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