KEGG T00736: Amuc

Akkermansia muciniphila: Amuc_0065

Entry

Amuc_0065 CDS T00736

Definition

2-isopropylmalate synthase

Orthology

K01649

2-isopropylmalate synthase [EC:2.3.3.13]

Organism

amu Akkermansia muciniphila

Pathway

amu00290	Valine, leucine and isoleucine biosynthesis
amu00620	Pyruvate metabolism
amu01100	Metabolic pathways
amu01110	Biosynthesis of secondary metabolites
amu01210	2-Oxocarboxylic acid metabolism
amu01230	Biosynthesis of amino acids

Module

amu_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Class

Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:amu00620]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine biosynthesis [PATH:amu00290]

SSDB

Motif

Pfam:

HMGL-like LeuA_dimer

Other DBs

NCBI-GI:

NCBI-GeneID:

JGI:

UniProt:

Position

87991..89547

AA seq 518 aa
MSDQIYFFDTTLRDGEQCPGASMNLREKLEVARQMERLGMDVIEAGFPCISDGDFEAVHT
IAREIKKCRIAGLARCVKADIEAAAKALEPAGERARIHIFLATSKLHMQFKLKKAESEIL
RMAAEGVSYAKQFVQDVEFSPEDASRTDLDFLTKVVETVIDAGATTVNIPDTVGYTTPDE
FYRIIRHLKENVPNIGKAVISVHCHNDLGLAVANSLAAVRAGARQVEGTINGIGERAGNV
ALEEVIMALRTRAGQFGDVTDNINTKEIVRTSRIVARMSGMQVQRSKAIVGENAFAHSSG
IHQHGILNCRETYEVMDPQAVGWGATELPLTKHSGRAAVKSRLEQLGHVLTEEEVNTVFE
RFKKVGDSKKFVYDDDLSAIVDDSLHASTGLWELDFLQFVAGSHARPTATVGLLKEGKKF
EDSSTGNGAVDAVIKAIERITRRKGTLKGYSVNAASEGKDALGEVTVHVDFGQPKPIVGK
GASTDVIEASARAYLNAVNRSIRMENMPQPNNLDAGTI

NT seq 1557 nt +upstreamnt +downstreamnt
atgtccgatcaaatctacttttttgacactaccctgcgcgatggagaacaatgccccgga
gcatccatgaacctacgcgaaaagctggaagtggcgcgtcaaatggaacggctgggcatg
gacgtgattgaagccggctttccctgcatctccgacggcgactttgaagccgtgcacacc
atcgcccgcgaaatcaaaaaatgccgcatcgctggtctggcccgctgcgtaaaggcggac
attgaagcggcggccaaagccctggaacccgccggggaacgtgcccgcatccacattttc
ctggccaccagcaagctgcacatgcagttcaaactgaaaaaagcggaatccgaaatcctg
cgcatggccgcggaaggcgtatcctatgccaaacaatttgtccaggacgtggaattttcc
ccggaggacgcttcccgcacagacctggacttcctgaccaaagtcgtggaaacagtcatc
gacgccggcgccactaccgtcaacattccggataccgtgggctacaccacaccggacgag
ttctaccgcatcatccgccacctgaaggaaaatgtgccgaacatcggcaaagccgtcatc
tccgtgcattgccacaatgaccttggcctggccgtagcaaactccctggcagccgtccgc
gccggagcccgccaggtggaaggaaccattaacggcatcggcgaacgcgccggaaacgtg
gctctggaagaggtcatcatggccctgcgcacccgcgccggacaattcggagacgtcacg
gacaacatcaacacgaaggaaatcgtccgcacttcccgcatcgtggcccgcatgagcggc
atgcaggtgcagcggtccaaagccatcgtgggggaaaacgctttcgcccactcttcaggc
atccaccagcacggcatcctcaactgccgggagacctatgaagtcatggacccgcaggcg
gtcggctggggagccacggaactcccgctcaccaagcattccggacgcgctgccgtcaaa
tccaggctggaacagctgggccatgtccttacggaagaggaagtcaacaccgtctttgaa
cgcttcaagaaagtgggcgactccaaaaaattcgtttatgatgatgatctttccgccatt
gtggacgactccctgcatgcctccaccggtctatgggaactggacttcctgcaattcgtg
gcaggcagccacgcgcggcccacggctacggtgggactgctcaaggaaggcaagaaattt
gaagacagctccacgggcaatggcgccgtggacgccgttatcaaagccattgagcgcatc
accaggcgcaaaggcacgctgaaaggctacagcgtcaacgccgcttccgaagggaaggac
gctctgggagaagtaacagtgcatgtggacttcggccagcccaagcccattgtgggcaag
ggagcctccacagatgtcattgaagcttccgcccgggcctacctgaacgcggtcaaccgt
tctatccgcatggaaaacatgccccagcccaataatctggatgcaggaaccatctaa

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   JGI-AMU (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (24)   

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