KEGG   Amycolatopsis mediterranei RB: B737_1711
Entry
B737_1711         CDS       T02804                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
amz  Amycolatopsis mediterranei RB
Pathway
amz00290  Valine, leucine and isoleucine biosynthesis
amz00660  C5-Branched dibasic acid metabolism
amz01100  Metabolic pathways
amz01110  Biosynthesis of secondary metabolites
amz01210  2-Oxocarboxylic acid metabolism
amz01230  Biosynthesis of amino acids
Module
amz_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:amz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    B737_1711 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    B737_1711 (leuC)
Enzymes [BR:amz01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     B737_1711 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     B737_1711 (leuC)
SSDB
Motif
Pfam: Aconitase AcnX
Other DBs
NCBI-ProteinID: AGT82375
Position
1857641..1859074
AA seq 477 aa
MTSPTGKARTLAEKVWESHLVRRGEGAEPDLLYIDLHLLHEVTSPQAFDGLRLAGRPLRR
PDLTIATEDHNVPTVDIELPIADPVSRTQVDTLRRNCKEFGVRLHPMGDAEQGIVHVIGP
QLGLTQPGMTVVCGDSHTSTHGAFGAIAFGIGTSEVEHVMATQTLPLRPFKTMAITVDGE
LRPGVTAKDIILAVIAKIGTGGGQGYILEYRGQAIEALSMEARMTVCNMSIEAGARAGMI
APDETTFEYLKGRPHAPQGADWDAAVENWRQLRTDDGAEFDAEVHLDASALTPFVTWGTN
PGQGLPLGAEVPDPEAIPDENDRIAAEKALSYMDLKPGTPLREIAVDTVFLGSCTNGRIE
DLRAAAEVLRGRKVADSVRMLVVPGSMRVRKAAEEEGLDQVFTEAGAEWRQAGCSMCLGM
NPDQLKPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDLLTAAR
NT seq 1434 nt   +upstreamnt  +downstreamnt
atgaccagcccgaccggcaaggcccgcacactggcggagaaggtgtgggaaagccacctc
gtgcgccgaggcgaaggcgccgaaccggacctcctctacatcgacctccacctgctgcac
gaagtcaccagcccgcaggccttcgacggcctccgcctggccgggcgaccgctgcgccgc
cccgacctgaccatcgcgaccgaggaccacaacgtcccgaccgtcgacatcgagctgccc
atcgccgatccggtctcgcgcacccaggtcgacacccttcgccgcaactgcaaggagttc
ggcgtccggctgcacccgatgggtgacgccgagcaggggatcgtgcacgtcatcggcccg
cagctcggcctgacccagcccggcatgaccgtggtctgcggcgacagccacacctccacg
cacggcgcgttcggcgccatcgccttcggcatcggcacgtccgaggtcgagcacgtgatg
gcgacccagacgctgccgctgcgtccgttcaagacgatggcgatcaccgtcgacggcgag
ctgcggcccggcgtcacggcgaaggacatcatcctcgcggtgatcgcgaagatcggcacc
ggcggcggccagggctacatcctggagtaccgcggccaggccatcgaggcgctctcgatg
gaggcgcggatgaccgtctgcaacatgtcgatcgaagccggcgcccgcgccgggatgatc
gcgccggacgagacgacgttcgagtacctgaagggccgtccgcacgcaccgcagggcgcg
gactgggacgcggcggtcgagaactggcggcagctgcgcaccgacgacggcgccgagttc
gacgccgaggtgcacctcgacgcgagtgcgctgacgccgttcgtgacctggggcaccaac
cccggccagggtctcccgctgggcgccgaggtgcccgacccggaggcgatcccggacgag
aacgaccgcatcgccgctgaaaaagccctgtcctacatggacttgaagccgggcacgccg
ctgcgggagatcgccgtcgacaccgttttcctcggctcctgcaccaacggccggatcgag
gacctgcgggccgcggccgaggtgctgcgcggtcggaaagtggcggactcggtccggatg
ctggtggttcccggctcgatgcgggtccgcaaggcggccgaggaggagggcctcgaccag
gtcttcaccgaggcgggcgccgagtggcggcaggcaggctgctcgatgtgcctcggcatg
aacccggaccagctgaagccgggggagcgcagcgcgtcgacgtcgaaccgcaacttcgag
ggccggcagggcaagggcggccggacgcacctggtctcgccgctcgtggccgccgccacg
gccgtccggggcacgctgtcgtcgccggaagacctgctgaccgccgcccgctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (48)   

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