KEGG   Actinobacillus pleuropneumoniae JL03 (serotype 3): APJL_0414
Entry
APJL_0414         CDS       T00644                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
apj  Actinobacillus pleuropneumoniae JL03 (serotype 3)
Pathway
apj00290  Valine, leucine and isoleucine biosynthesis
apj00620  Pyruvate metabolism
apj01100  Metabolic pathways
apj01110  Biosynthesis of secondary metabolites
apj01210  2-Oxocarboxylic acid metabolism
apj01230  Biosynthesis of amino acids
Module
apj_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:apj00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    APJL_0414 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    APJL_0414 (leuA)
Enzymes [BR:apj01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     APJL_0414 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer NAD_binding_10
Other DBs
NCBI-ProteinID: ABY69003
UniProt: B0BTP8
Position
453021..454562
AA seq 513 aa
MSNIIIFDTTLRDGEQSLKASLTVKEKLQIALALERLGVDVMEVGFPVSSAGDFESVKTI
AQHIKNSSVCALSRAVDKDIDVAAEALKVAEAFRIHTFIASSAIHVESKLKRSFDDVVEM
AVHAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGYCLPYQYG
EIIANVMNRVPNIDKAVVSVHCHNDLGMATANSLTAVLNGARQIECTINGIGERAGNTAL
EEVVMAIKTRQDMFNGRDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIH
QDGMVKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKNHMSEMGYQENDYDLDKLYDAF
LKLADKKGQVFDYDLEALAFIDMQAGDEGRLHLDVITSQMISHLPASAFVQVELDGEKLS
QVSSGGNGPVDAVFNAILAITGMDIKMLHYNLTAKGEGAEALGQVDIVVEHEGRRFHGVG
LATDIVESSARALIHAINAIYRAHKVADLKAKK
NT seq 1542 nt   +upstreamnt  +downstreamnt
atgagtaacattattatttttgatacgacattacgtgacggtgaacaatcgcttaaagca
agtttaaccgtaaaagaaaaactacaaattgcgttagcattagagcgtttaggcgttgat
gttatggaagtcggttttccggtttcatcggcaggggatttcgagtcggtaaaaaccatt
gctcaacacattaaaaacagcagtgtttgcgcattatcccgcgcagtggataaagatatt
gatgtggcggcggaagcattgaaagtcgcagaagcatttcgtattcatacatttatcgcc
agttccgctattcatgttgagtctaaattaaaacgttcgtttgatgatgtcgttgaaatg
gcggtgcatgcggttaaacgtgccagaaactataccgatgatgtggagttttcctgtgaa
gatgcgggacgtaccggtattgataacatttgtcgtattgtcgaagcggcaatcaatgcc
ggtgcgactacggtaaatattccggatacggtcggttactgtttaccgtatcagtacggc
gagattatcgccaatgtgatgaaccgtgtgccgaatattgataaagcggttgtttcggtg
cattgtcataacgatttaggtatggcgacggcaaactcgctcacggcagtgttaaatggt
gcgagacaaatcgaatgtacgattaacggtatcggtgagcgtgcggggaataccgcatta
gaagaagtggtcatggcaatcaaaactcgccaagatatgttcaatggtagagatacgcgc
attaacacgcaagaaattcatcgtgtcagccaaatggtcagccaattatgtaatatgccg
attcaaccgaataaagcgattgtcggttcgaatgcctttgcccattcatccggtatccac
caagacggtatggtaaaaaataaaaatacctatgaaattatgtcgcctgaaaccatcggt
ttgaagaaagaaaaattaaatttaaccgcccgttcaggacgtgccgccgtgaaaaatcat
atgagcgaaatgggttatcaagaaaacgactatgatttggataaactttatgacgcattc
ctaaaattggcggataagaaaggtcaagtgtttgattacgatttagaagcgcttgctttt
attgatatgcaggcaggtgatgaaggcagattacatttagacgtgattacttcgcaaatg
attagccatttaccagcttcggcatttgttcaagtcgaattagacggtgaaaaattaagc
caagtttccagtggcggtaacgggccagtcgatgcggtctttaatgcgattctagccatt
acggggatggatattaaaatgttacattataaccttaccgcaaaaggcgaaggtgcggaa
gcattaggtcaagtggatattgtggttgaacacgaaggtcgccgcttccacggtgtcggt
ttggcaaccgatattgtcgagtcttcggcgcgtgcgttaatccatgcgatcaatgcgatt
tatcgagcgcataaagtggcggatttaaaagctaaaaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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