KEGG   Actinobacillus pleuropneumoniae L20 (serotype 5b): APL_0587
Entry
APL_0587          CDS       T00476                                 
Symbol
acrB
Name
(GenBank) acriflavine resistance protein
  KO
K18138  multidrug efflux pump
Organism
apl  Actinobacillus pleuropneumoniae L20 (serotype 5b)
Pathway
apl01501  beta-Lactam resistance
apl01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:apl00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    APL_0587 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    APL_0587 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:apl02000]
    APL_0587 (acrB)
   01504 Antimicrobial resistance genes [BR:apl01504]
    APL_0587 (acrB)
Transporters [BR:apl02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   APL_0587 (acrB)
Antimicrobial resistance genes [BR:apl01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    APL_0587 (acrB)
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF Macro DUF678
Other DBs
NCBI-ProteinID: ABN73689
UniProt: A3MZV3
Position
667281..670400
AA seq 1039 aa
MKFTDIFIKRPVLAVCISLLITILGLQSINKLQVREYPEMTISIVTVKVNYSGADASLMQ
ALVTSQIEEAVAQADNIDYVTSSSGPSSSTTTIKMKLNTNPQMALADISAKVNAIRANLP
SGIDDPSISVSSGSNDALMYIRFVSDELSTPQITDYINRVVKPQFFTVNGVSSVDIFGAA
NFGLRIWLDPDKMAGNNLSGAAVLSALSANNLNTAAGNANGYYTVYKNKVESSTPSVEEL
ENVTISTTSDGRIVKLKDIAKVELDKYQDASRAIADGKEAVVLAVSAATTANSLTVAKDI
YPVFDLITKNLPSSVNGQIMYDKTVAINSSINEVIKTIGEATVIVLAVIILFLGSLRAMI
VPIITIPISLIGVLFFLQMFGFSINLLTLLALVLAIGLVVDDAIVVLENVERHVKEGKTP
FDAAIIGTREIALPVISMTITLAAVYSPMALMEGVTGSLFKEFALTLAGAVFISGIAALT
LSPMMSSRVLKEHNEENESRFSKCINTMLDKMTACYTNMLRGVMSVRWLVVIFAMSIFAV
LPTLLTSLSSEVAPTEDRGFVVGIGNGPSNTNLDYTQAATEKFNEDVGKIPEVASMMTVS
GFNGANSALSIISLKDWSERERERKPISADVSAIAKNVVGMDINAISFPEISTGENGLPF
SLVITTADNYVKLADVANDFLKKAQASGQFFFSSLDLKFDTVTMKWKFDREKMGTYGVTM
QQVSGTLGAYLSGAIITRVDIDSRAYPIVSQAVRQDRLNPQDLVNYYVTTASGESVPLSS
FVSLELSTEPAALPRMNQLNSATISGVVSSSIGDAVNWAKAELDRSLPQGYQYDFKSEAR
QYVQEGNAMAMTFALAVVIIYLVLAIQFESWRDPMVILVSVPLALSGALVVLNVLGIAGI
AGATLNIYSQVGLVTLVGLITKHGILMCEVAKEEQLHNGLSRFDAIVHSATIRLRPIMMT
TAAMVAGLIPLLFAMGAGAIARFSMGMVIVAGLSIGTLFTLFVLPVIYTFLGQEHKPLRE
FDEEKYAKASVEKIEHTGM
NT seq 3120 nt   +upstreamnt  +downstreamnt
atgaaatttactgatatttttattaaacgtccggtacttgccgtttgtattagtttgcta
attaccattttaggtttgcaatctattaacaaacttcaagtacgcgaatatcccgaaatg
acgatttccattgtcacggtaaaagtcaattattcgggtgcggatgcaagccttatgcag
gcattggtaacttctcaaattgaagaagcggtagcgcaggcggataatatcgactatgtt
acttcatcaagcggtcctagttcttccacgacaacgattaagatgaagttaaataccaat
ccgcaaatggcgctcgcggatatttctgcgaaggtaaatgcgattcgtgcgaatttgccg
agcggtattgacgatccgtccattagcgtttcgtccggttcgaacgatgcgttaatgtat
atccgtttcgtttcggatgaactttctacaccgcaaattaccgactatatcaatcgtgtg
gttaaacctcaattctttacggtaaacggcgtttcgagcgtagatattttcggtgcggcg
aacttcggtttacgtatttggttagacccggacaaaatggcgggaaataacctttccggt
gcggcggtattatcggcgttaagtgcgaataacttaaatacggctgccggtaatgcgaac
ggttattacacggtttataagaacaaagtggaatccagtacgccgtctgtcgaagaactg
gaaaacgtaaccatttcgacaacttccgacggtcgtatcgttaaacttaaagatattgca
aaagttgaattggataaatatcaagacgcttcccgagctatcgcagacggtaaagaagcg
gttgtattagcggttagtgccgcaacaacggctaactcgcttacggtggcaaaagatatt
tatccggtatttgaccttatcactaaaaatttaccgtcgtcagtgaacggtcaaattatg
tatgataaaacggttgcaattaacagctcgattaatgaggtaattaaaactatcggagag
gcgacagttatcgtattagcggtaatcattcttttcttaggatcattacgcgcaatgatt
gtgccgattattactattccgatttcattgatcggggtgttattcttcctgcaaatgttc
ggattctctattaacttattaaccttgttagcgttagtgttggcaatcgggcttgtggtg
gacgatgcgattgtggtgttggaaaacgtcgaacgccacgtaaaagaagggaaaacaccg
tttgatgcggcgatcatcggtacacgtgaaatcgccttaccggtaatttcaatgactata
acacttgctgcggtatattctccgatggcattaatggaaggcgttaccggctctttattt
aaagagtttgcactaacgcttgccggtgcggtatttatttcagggattgcggcattaacc
ttatctccgatgatgtccagccgagtattaaaagagcataatgaagaaaacgaaagtcgt
ttctcaaaatgtatcaatacaatgctagataaaatgaccgcttgttataccaatatgtta
agaggtgtgatgtcggtacgttggttagtggttatctttgcaatgagcatttttgcggta
ttaccgacgttattaacttctctttccagtgaggttgcaccgaccgaagaccgtggattc
gtggtcggtatcggtaacggcccgtccaataccaacttagattatacgcaagcggcaaca
gaaaaatttaatgaagatgtcgggaaaattccggaagtcgcatcgatgatgactgtttcc
ggttttaacggcgcaaacagtgccttatcaattatttcattaaaagactggagcgagcgt
gagcgtgaacgtaaaccgatttcggcggacgtttctgcaattgcgaaaaacgtagtcggt
atggatattaacgcaatttccttcccggaaatttcaaccggtgaaaacggtttaccgttc
tcattggtaattactacggcggataattatgtgaagctagccgatgtcgcgaacgacttc
ttgaaaaaagcgcaagcatcgggtcaattcttcttctcaagtctggatttgaaatttgat
acggtcacgatgaaatggaaatttgatcgtgagaaaatggggacttacggtgtaacgatg
caacaggtaagcggtacgttaggagcatatttatccggcgcgattattacgcgtgttgat
atcgactctcgtgcttatccgattgtgtcgcaagcggttcgtcaagatcgattaaatccg
caggatttggttaattactatgtaaccaccgcaagtggcgagtccgtgccgttaagttcg
tttgtttctttagaattatcaacggaaccggcggcgttacctcgtatgaaccagttaaat
tccgcaacgatttccggtgtggtatccagctcaatcggtgatgcggtaaattgggctaaa
gcggagcttgatcgcagcttaccgcaaggttatcaatacgactttaaatccgaagcgcgc
caatatgtacaagaaggtaatgcaatggcgatgacatttgctttagccgtcgtgattatc
tatcttgttcttgcgattcagtttgaatcttggcgtgatccgatggtaattttggtttcg
gtaccgcttgcattaagtggcgctttagtcgtactaaatgtgttaggtattgccggaata
gccggtgcaactttaaatatctattcgcaagtaggtttagtaacgttagtcggtttgatt
actaagcacggtatcttaatgtgcgaagtggcgaaagaagaacagttacataacggctta
tcccgttttgatgcgatcgttcattcggcaactattcgtttacgcccgattatgatgacg
accgcggcgatggtggccggcttgatcccgttattgtttgcaatgggtgcaggggctatt
gctcgtttcagtatggggatggtgattgttgccggtttaagcatcgggacattatttacc
ttgtttgtactaccggttatttataccttcttaggacaagagcataaaccgcttcgtgaa
ttcgacgaagaaaaatatgctaaagcgtccgtagaaaaaatcgagcataccggtatgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (26)   

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