KEGG T02250: HIMB5

Alpha proteobacterium HIMB5: HIMB5_00012840

Entry

HIMB5_00012840 CDS T02250

Definition

Biotin-requiring, e3 domain-containing 2-oxoacid dehydrogenase with acyltransferase acitivity family protein

Orthology

K00627

pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]

Organism

apm Alpha proteobacterium HIMB5

Pathway

apm00010	Glycolysis / Gluconeogenesis
apm00020	Citrate cycle (TCA cycle)
apm00620	Pyruvate metabolism
apm01100	Metabolic pathways
apm01110	Biosynthesis of secondary metabolites
apm01120	Microbial metabolism in diverse environments

Module

apm_M00307

Pyruvate oxidation, pyruvate => acetyl-CoA

Class

Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:apm00010]
Metabolism; Carbohydrate metabolism; Citrate cycle (TCA cycle) [PATH:apm00020]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:apm00620]

SSDB

Motif

Pfam:

2-oxoacid_dh Biotin_lipoyl Biotin_lipoyl_2 HlyD GCV_H PYNP_C E3_binding HlyD_2 NQRA HlyD_3 Crystall_2

Other DBs

NCBI-GI:

406706848

NCBI-GeneID:

13674615

UniProt:

J9YWB6

Position

complement(1177424..1178683)

AA seq 419 aa
MSQTEIKVPNIGDFKDVEVIEVLVKEGDEVKKNDPLITIESDKSSVEIPSTVDGKIIKLN
LKIGDKVSEGDNILQIEINTKSNEKPSKNIEVKKEEKGSQKQIKEIQPSSVVEINTEGGF
ALASPKTRKFARELGVNINLIKGSQLKGRVDETDIKNFISSGNNSLHYEDKKNKKLELEF
QHDEFGSIEVKDIPRVKKLASTYLSNSWSNIPHVTNHDEADITELENFRSSLTDIYTGEK
KKITPLAFIVKALTASLKKFPSFNSSIDEIEDGKMTLKKYFHIGIAVDTKHGLMVPKLRN
ANNKSISNIAAELKNLSELCKNLKIDKKELFGGSMTITSLGGIGGSFFTPIINYPEVAIL
GIGKAEKKQKFINGKFETRTILPISLSYDHRIIDGAEAARFNNDLKENLGKNFAYKLAV

NT seq 1260 nt +upstreamnt +downstreamnt
atgtcacaaactgaaataaaagttccaaacataggagattttaaagatgtggaggtaata
gaagttttagttaaagaaggtgatgaagttaaaaaaaatgatccgctaataacaattgaa
agtgataaatctagtgttgaaattcctagcacggtagatggtaaaattattaagcttaat
ttaaaaattggtgacaaagtttcagaaggagacaatattttacaaattgaaataaatact
aaatctaatgaaaaaccatcaaaaaatattgaagtaaaaaaagaggaaaaaggaagtcaa
aaacaaatcaaagaaatacaaccaagttcggtagtagaaataaatacagagggaggattt
gctttagcatcaccaaaaactcgaaagtttgcgagagaattaggcgttaatattaattta
attaaaggcagtcaactaaaaggaagagtagatgaaactgatataaagaattttatttca
tcaggaaataatagtttacattatgaagataaaaaaaataaaaaattagaattagaattt
caacatgatgagtttgggtctattgaggtaaaagatattcctcgggtaaaaaaattagca
tctacttacctttcaaactcttggtctaatattcctcatgtaacaaatcatgatgaagct
gacataactgaactagaaaattttcgatcatcattgactgacatttatactggagaaaaa
aaaaagataactccattagcgtttattgttaaagccctaactgcatcattaaaaaaattt
cctagttttaattcttcaattgatgaaattgaagatggaaaaatgacattaaaaaaatat
tttcatataggtattgctgttgatactaagcatggtttgatggtgcctaaattaagaaat
gcaaataataaaagtatatctaatatagctgctgagctaaaaaatttgagtgaattatgt
aaaaatcttaaaattgataaaaaagaattatttggtggatctatgaccattacaagctta
ggaggtataggtggttcattttttactcctattattaattacccagaagttgccatttta
gggattggtaaagcagaaaagaagcagaaatttataaatggaaagtttgaaactagaaca
attctaccaatttcactatcatatgatcacagaataattgatggtgctgaagcagcaaga
tttaataatgatttaaaagaaaatcttggcaaaaattttgcgtataaacttgctgtttaa

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (31)   

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