KEGG   Actinoplanes sp. SE50/110: ACPL_7861Help
Entry
ACPL_7861         CDS       T02044                                 

Gene name
hemD
Definition
uroporphyrinogen III methyltransferase / synthase (EC:4.2.1.75)
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
ase  Actinoplanes sp. SE50/110
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
Heme biosynthesis, glutamate => protoheme/siroheme
Brite
KEGG Orthology (KO) [BR:ase00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    ACPL_7861 (hemD)
Enzymes [BR:ase01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     ACPL_7861 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     ACPL_7861 (hemD)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
complement(8674274..8675860)
Genome map
AA seq 528 aa AA seqDB search
MTTRTARKPAGRIAFIGAGPGDPELLTRRAYAALTDADQVVHDRGVPESLLAAVRADAKP
DAQFSPAEGAPGDVAKVLLSAAKSGLSAVHLVAGDPFGHESVVKEVQAVARTAVHFEVIP
GIGQAEGVAAYAGVPLPGVRIAADVDDVTSLDFDALAGAAQKGSFAVAVDAGDLAAVRDG
LLAAGVEPGVPVAVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTVGAEVAERDAMSW
WENRPLYGWKVLVPRTKEQAGAMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVD
GRYAWVVFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGEATAEAVRDFGIQPELIPAG
EQSSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLIERGWEVDDVTAYRTVRAAP
PPAEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETAVEFGLRVD
TQPQNASVPDLVEALAEYALELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq 1587 nt NT seq  +upstreamnt  +downstreamnt
atgaccacccgcaccgcccgtaagccagccggacgcatcgcgttcatcggcgccggaccc
ggcgacccggagctgcttacccgccgcgcgtacgccgcgttgaccgatgccgaccaggtg
gtccacgaccggggcgtacccgagtcgctgctggccgcggtccgcgcggacgccaaaccc
gacgcgcagttcagcccggccgagggcgcccccggcgacgtggccaaggtgctgctctcc
gccgccaagtccgggctgtccgccgtccacctggtggccggcgacccgttcggccacgag
tcggtggtcaaggaggtgcaggcggtcgcccggaccgcggtgcacttcgaggtgatcccg
ggcatcgggcaggccgagggtgtcgccgcgtacgccggcgtgccgctgcccggcgtgcgg
atcgccgccgacgtcgacgacgtcacctcgctcgacttcgacgcgctggccggcgcggcc
cagaagggctcgttcgcggtcgccgtggacgccggcgacctcgccgcggtccgcgacggg
ctgctcgcggccggcgtcgaaccgggtgtcccggtcgcggtgaccggcgacggcaccggc
gagacgcagtacaccaccacctcgacggtggacagcttcgtggccgccgcgctcggcttc
accggccgggtggtgctcaccgtcggggccgaggtcgccgagcgggacgcgatgagctgg
tgggagaaccgcccgctgtacggctggaaggtcctggtcccgcggaccaaggagcaggcc
ggcgcgatgagcgcgcggctgcgggcgtacggcgccatcccgtgcgaggtgccgaccatc
gcggtcgagccgccgcgcaccccggcgcagatggagcgcgcggtcaagggcctggtcgac
ggccgctacgcctgggtggtgttcacctcggtgaacgccgtccgcgcggtctgggagaaa
ttcgccgagcacggcctcgacgcccgtcacttcggcggtgtgaagatcgcctgcatcggg
gaggccaccgccgaggcggtccgcgacttcggcatccagcccgagctgatcccggccggc
gagcagtccagcgagggcctgctggccgagttctcgccgcacgacgagatcctcgacccg
gtcggccgggtgctgctgccgcgcgccgacatcgccaccgagaccctggccgccggcctg
atcgagcggggctgggaggtggacgacgtgaccgcgtaccggacggtgcgggccgcgccg
ccgccggccgagatccgcgacgcgatcaagtccgggggcttcgacgcggtgctgttcacc
tcgtcctccacggtccgcaacctggtcggcatcgccggcaagccgcacgcccgcacggtc
gtcgcggtgatcgggccgaaaaccgcggagaccgcggtcgagttcggcctgcgggtcgac
acccagccgcagaacgcctcggtgccggacctggtcgaggcgctcgccgaatacgccctg
gagctgcgcgagaaactggcggcgatgcccgccaagcagcgccgcggctcgaaggtgcag
ggcccgacggccctccgattccgctga

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