KEGG   Balaenoptera acutorostrata scammoni (minke whale): 102998192
Entry
102998192         CDS       T03086                                 
Symbol
LCK
Name
(RefSeq) LCK proto-oncogene, Src family tyrosine kinase
  KO
K05856  lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu04064  NF-kappa B signaling pathway
bacu04380  Osteoclast differentiation
bacu04650  Natural killer cell mediated cytotoxicity
bacu04658  Th1 and Th2 cell differentiation
bacu04659  Th17 cell differentiation
bacu04660  T cell receptor signaling pathway
bacu05135  Yersinia infection
bacu05166  Human T-cell leukemia virus 1 infection
bacu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bacu05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:bacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    102998192 (LCK)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    102998192 (LCK)
   04660 T cell receptor signaling pathway
    102998192 (LCK)
   04658 Th1 and Th2 cell differentiation
    102998192 (LCK)
   04659 Th17 cell differentiation
    102998192 (LCK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102998192 (LCK)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102998192 (LCK)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102998192 (LCK)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102998192 (LCK)
  09163 Immune disease
   05340 Primary immunodeficiency
    102998192 (LCK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    102998192 (LCK)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:bacu03036]
    102998192 (LCK)
Enzymes [BR:bacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     102998192 (LCK)
Protein kinases [BR:bacu01001]
 Non-receptor tyrosine kinases
  SRC family
   102998192 (LCK)
Chromosome and associated proteins [BR:bacu03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    102998192 (LCK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH3_16 SH3_3 Kdo Haspin_kinase
Other DBs
NCBI-GeneID: 102998192
NCBI-ProteinID: XP_007170673
UniProt: A0A383Z669
Position
Un
AA seq 509 aa
MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKAMLSIWNGSEVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRVLEQNGEWWKAQSVTTGQEGYIPFNFVARAN
SLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTTGSFSLSVRDFDQTQGEVVKH
YKIRNLDKGGFYISPRITFPGLHELVRHYMNSSDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTSAGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLEQGYRMVRPDNCPDELYHLMMLCWKEL
PEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq 1530 nt   +upstreamnt  +downstreamnt
atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtatgt
gagaactgccattaccccatagtcccactggatggcaaggccatgctgtccatctggaat
ggctctgaagtgcgtgatccactggtcacctacgagggctccaaccccccagcttctccg
ctgcaagacaacctggttatcgccctgcacagctatgagccttcccacgatggagacctg
ggcttcgagaagggtgaacagctacgtgtcctggagcagaacggcgagtggtggaaggcg
cagtccgtgaccacgggccaggaaggctacatccccttcaactttgtggccagagcgaac
agcctggagcccgaaccctggttcttcaagaccctgagccgcaaggacgcggagaggcag
ctcctggcgcccgggaacacgcacggctccttcctgatccgagagagtgaaagcaccact
ggatcgttttcactgtccgtccgggacttcgaccagacccagggagaagtggtgaaacat
tacaagatccgtaacctggacaaaggcggcttctacatctccccccgcatcacttttcct
ggcttgcatgagctggtccgccattacatgaattcttcggacgggctgtgcacgaggttg
agccgcccctgccagacccagaagccccagaagccgtggtgggaggatgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggggctggccagttcggagaggtgtgg
atggggtactacaacgggcacacgaaggtggcagtgaagagcctgaagcagggcagcatg
tcccccgatgccttcctggccgaggccaacctcatgaagcagctgcagcaccagcggctg
gtccggctctacgcggtggtcacccaggagcccatctatatcatcacggaatacatggag
aatgggagcctggtggattttctcaagacctccgcaggcatcaagctgaccatcaacaaa
ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagagcggaattac
atccaccgtgacttgagggccgccaacatcctggtgtctgacaccctgagctgcaagatc
gcagactttggcctagcacgcctcattgaggacaatgagtacacagccagggagggggcc
aagtttcccattaagtggacagcaccagaagccattaactatgggacatttaccatcaag
tcggacgtgtggtctttcgggatcctgctgacggagattgtcactcatggccgcatccct
tacccagggatgaccaatcctgaggtgattcagaacctggaacaaggctaccgcatggta
cgacctgacaactgtccagatgagttgtaccaccttatgatgctgtgctggaaggagctc
ccggaggaccggcccacctttgactacctgcgcagcgtgctggaggacttcttcacagcc
acagagggccagtaccagccgcagccctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (37)   

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