KEGG   Balaenoptera acutorostrata scammoni (minke whale): 103018249Help
Entry
103018249         CDS       T03086                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:bacu00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    103018249 (INSR)
   04015 Rap1 signaling pathway
    103018249 (INSR)
   04010 MAPK signaling pathway
    103018249 (INSR)
   04066 HIF-1 signaling pathway
    103018249 (INSR)
   04068 FoxO signaling pathway
    103018249 (INSR)
   04072 Phospholipase D signaling pathway
    103018249 (INSR)
   04022 cGMP - PKG signaling pathway
    103018249 (INSR)
   04151 PI3K-Akt signaling pathway
    103018249 (INSR)
   04152 AMPK signaling pathway
    103018249 (INSR)
   04150 mTOR signaling pathway
    103018249 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    103018249 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    103018249 (INSR)
   04923 Regulation of lipolysis in adipocyte
    103018249 (INSR)
   04913 Ovarian Steroidogenesis
    103018249 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103018249 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    103018249 (INSR)
   04213 Longevity regulating pathway - multiple species
    103018249 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    103018249 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    103018249 (INSR)
   04931 Insulin resistance
    103018249 (INSR)
Enzymes [BR:bacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103018249 (INSR)
Protein kinases [BR:bacu01001]
 Tyrosine protein kinases
  InsR family [OT]
   103018249 (INSR)
Enzyme-linked receptors [BR:bacu01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   103018249 (INSR)
Cytokine receptors [BR:bacu04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   103018249 (INSR)
CD molecules [BR:bacu04090]
 Proteins
  103018249 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 1316 aa AA seqDB search
MFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFE
MVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGD
ICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCS
EPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQGCHQY
VIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTIIN
GSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGN
YSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDI
ALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQNVTE
FDGQDACGSNSWTVVDIDPPMRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERR
TYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQEE
DGELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEDSAGECCSCPKTDSQILKELE
ESSFRKTFEDYLHNVVFIPRKSSSGPVAEDTRPSRKRRALGDVGNVTAAVPTIPGFPNTS
STSAPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPERCSVAAYVSARTM
PEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCVSRRHF
ALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYYVPSNIAKIIIGPLIFVF
LFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLL
RELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHV
VRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADG
MAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPE
SLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVT
DLMRMCWQFNPKMRPTFLEIVDLLKDELHPSFPEVSFFHSEENKVPESEELEMEFEDMES
VPLDRSSHAQREEAGGRDGGSALGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNPS
NT seq 3951 nt NT seq  +upstreamnt  +downstreamnt
atgttcaaaacgagacctgaggacttccgagacctcagtttccccaagctcatcatgatc
actgattacttgctgctcttccgggtctacgggctggagagcctgaaggacctgttcccc
aacctcacggtcatccggggctcccgcctcttctttaactacgcgctggtcatcttcgag
atggttcacctgaaggagcttggcctctacaacttgatgaacatcacccggggctccgtc
cgcatcgagaagaacaatgaactctgctacctggccaccatcgactggtctcgcatcctg
gattccgtggaggataattacatcgtgctgaacaaagacgacaatgaggagtgtggggac
atttgtcccggcaccgcgaagggcaagaccaactgccctgccaccgtcatcaacgggcaa
tttgtggagcggtgttggacgcacagccactgccagaaagtgtgtccgaccatctgtaag
tctcacggctgcaccgctgagggtctctgttgccacagtgagtgcttgggcaactgctct
gagcctgacgaccccaccaagtgtgtggcctgtcgcaacttctacctggatggcaggtgc
gtggagacctgcccgcccccctactaccacttccaagactggcgctgtgtgaacttcagc
ttctgccaggacctgcacaacaaatgcaagaactctcggaggcagggctgccaccagtat
gtcattcacaataacaagtgcatccctgagtgcccctctgggtacacgatgaattccagc
aacttgatgtgcactccatgcctgggcccctgtcccaaggtgtgccacctcctggaaggc
gagaagaccattgactcagtgacatctgcccaggagctccgaggctgcaccatcatcaac
ggaagcttaatcatcaacatccgagggggcaacaacctggcagctgagctagaggccaac
cttggactcattgaagaaatttcagggtatctgaaaatccgtcgatcatatgcactcgtg
tcactttccttcttccggaagttacgtctgattcgaggggagaccttggaaatcgggaac
tactctttctatgccttggacaaccagaacctaaggcagctgtgggactggagcaaacac
aacctcaccatcactcaggggaaactcttcttccactataatcccaaactctgcttgtca
gaaattcacaagatggaggaagtttccggaaccaaggggcgccaggagagaaacgacatt
gccctgaagaccaatggggaccaggcgtcctgcgaaaatgaattacttaaattttcttac
attcggacatcttatgacaagatcttgctgaaatgggagccgtattggccccccgacttc
cgagacctcctgggattcatgctcttctacaaagaggccccttatcagaacgtgacggag
tttgatgggcaggacgcgtgtggttccaacagctggaccgtggtggatattgacccgcct
atgaggtccaacgaccccaagtcacagaaccaccctgggtggctaatgcgtggtctcaag
ccctggacccagtacgccatctttgtcaagaccttggtcaccttttctgatgaacgccgc
acatacggggccaagagcgacatcatctatgtccagacagatgccactaatccttctgtc
cccctggatcccatctcggtgtctaattcttcgtcccagattattctgaagtggaagcct
ccctctgaccccaatggcaacatcacacactacttggtattctgggagagacaggaggaa
gacggtgaactgtatgaattagattattgcctcaaagggttgaagctgccctcccggacc
tggtctccaccgttcgagtctgaggggtcccagaagcacaatcagagtgagtacgaagac
tctgccggtgaatgctgttcctgcccgaagaccgactctcagatcctcaaggagctggag
gagtcctcattccggaaaacgttcgaagattacctgcacaacgtggttttcatccccaga
aaatcctcttcaggccctgttgccgaggacactaggccgtcgaggaaacgcagggccctt
ggtgatgtggggaatgtgacagcagccgtgcccaccattccgggattccccaatacgtcc
tcaaccagcgcacctacgagctcagaggagcacagaccattcgagaaagtggtgaacaag
gagtctctggtcatctctggcctgcggcactttactggctatcgcattgagctgcaggct
tgcaaccaagactcccccgagaggtgcagcgttgctgcatatgtcagtgccaggaccatg
cccgaagccaaggcagatgatattgttggccccgtgacccacgaaatcttcgaaaacaac
gtcgttcacttgatgtggcaggagcccaaggaacccaacggtctgatcgtgctgtacgaa
gtgagttatcgacgatacggcgaagaggagctgcatctctgcgtctcccgcaggcatttt
gctctggagcggggctgcaggctgcgtggtctgccacccgggaattacagtgtgcgagtt
cgggccacctccctggcgggcaatggctcctggacggaagccacctatttctacgtcaca
gactattacgtaccatcaaatattgcaaaaattatcatcggccccctcatctttgtcttt
ctcttcagtgttgtgatcggaagcatttatctattcctgagaaagaggcagccggatggg
ccactgggaccactgtatgcttcttcaaaccctgagtacctcagtgccagcgatgtgttt
ccctgctctgtgtacgtgccggatgagtgggaggtgcctcgagagaagatcacgctcctg
cgagaactggggcagggctccttcggcatggtgtacgagggcaacgccagggacattgtc
aagggcgaggcggagacccgagtggcagtgaagacggtcaacgagtctgccagcctgcga
gagcggatcgaatttctcaacgaggcctcggtcatgaagggcttcacctgccaccacgtg
gtccgcctcctgggggtggtatccaaaggccagccgacgctggtggtgatggagttgatg
gctcacggggacttgaagagctacctccgttccctgcggcctgaggccgagaataacccc
ggccgccctccccctaccctgcaagagatgattcagatggctgcggagatcgccgacggg
atggcatacctgaacgccaagaagtttgtacaccgggacctcgcagctcgaaactgtatg
gtcgcccacgattttactgtcaaaattggagactttggaatgaccagagacatctacgaa
acggattactaccggaaagggggaaagggtctgctccccgtgcggtggatggcacctgaa
tccctgaaggacggggtctttaccacttcttcggacatgtggtcctttggcgtggtcctt
tgggaaattaccagcttggcggaacagccttaccaaggcctatcaaacgagcaggtgtta
aaatttgtcatggatggagggtatctggatcaacccgacaattgtccagagagagtcacc
gacctgatgcgcatgtgctggcagttcaaccccaagatgcggccgaccttcctggagatt
gtcgacctgctcaaggacgagctgcaccccagtttccccgaagtttccttcttccacagc
gaggagaacaaggtgcccgagagcgaggagctggagatggaatttgaggacatggagagt
gtccccctggaccggtcgtcacatgcgcagagggaggaggccgggggccgggatggaggg
tccgcgctggggctaaagagaaactatgaggagcacatcccctacacccacatgaacggg
ggcaagaaaaacggacgcattctgactctgccccggtctaatccttcctaa

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