KEGG   Bos indicus (zebu cattle): 109560497
Entry
109560497         CDS       T04792                                 
Symbol
BACE2
Name
(RefSeq) beta-secretase 2
  KO
K07747  beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45]
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:biu00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109560497 (BACE2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:biu01002]
    109560497 (BACE2)
Enzymes [BR:biu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.45  memapsin 1
     109560497 (BACE2)
Peptidases and inhibitors [BR:biu01002]
 Aspartic peptidases
  Family A1: pepsin family
   109560497 (BACE2)
SSDB
Motif
Pfam: Asp TAXi_C TAXi_N
Other DBs
NCBI-GeneID: 109560497
NCBI-ProteinID: XP_019818369
UniProt: A0A6P5BYI4
Position
1:144149703..144261281
AA seq 514 aa
MGALARALLLPLLAQWLLRAAPALASAPFTLPLRVASATSQGAVXXXXXXPPEEPRAXGL
ALALEPAGGAANFLAMVDNLQGDSGRGYYLEMQIGTPPQKLQILVDTGSSNFAVAGAPHP
YIDSYFDAERSSTYRPKGFDVTVKYTQGSWTGFVGEDVVTIPKGFNSSFLVNIATIFESE
NFFLPGIRWNGILGLAYATLAKPSSSLETFFDSLVAQAKIPNIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPTLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSEGFWTGSQLACWTNSETPWSYFPKISIYLRD
ENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVVFDRAQK
RVGFAASPCAEIAGAPVSEISGPFSTEDIASNCVPALPLNEPVLWIVSYTLMSVCGVILL
VLITLLLLPVRCRHHPRDPEVVNDESSLVRHRWK
NT seq 1545 nt   +upstreamnt  +downstreamnt
atgggcgcgctggcccgggcgctgctgctgccgctgctggctcagtggctcctacgagcg
gccccggcgctggcctccgcgcccttcacgctgcctctccgggtggcctcggccacgagc
caaggggctgtgnnnnnnnnnnnnnnnngaccccctgaagagccccgcgcgsacggcctg
gcgctcgccctggagcccgctgggggtgcggccaacttcttggccatggtggataacctg
cagggggactctggccgcggctactacctggagatgcagatcgggacccccccgcagaag
ctgcagatactcgttgacaccggaagcagcaactttgccgtggctggggccccacatccc
tatatcgactcttactttgacgcggagaggtccagcacgtaccgccccaagggttttgat
gtcactgtgaagtacacacaggggagctggacgggcttcgttggggaggacgtggtcacc
atccccaaaggcttcaacagttcttttcttgtcaacattgccaccatatttgagtcagag
aatttctttctgcctgggattagatggaatgggatacttggactggcttatgctaccctg
gccaagccttcaagttctctggagaccttctttgattccctcgtggcacaagcaaaaatc
cccaacatcttctccatgcagatgtgtggggccggactgccagtagctggatctggtacc
aacggaggtagtcttgtcctaggtggaattgaaccaactttgtacaaaggagacatctgg
tacacccctattaaggaggagtggtattatcagatagaaattctaaaattggaaattgga
ggccagagccttaatctggactgcagagagtacaatgcggacaaggccatcgtggacagt
ggcaccacgctgctgcgcctgccccagaaggtgtttgacgccgtggtggaggctgtggcc
cgcacgtctctgattccagaattctctgaaggtttctggactggttcccagctggcatgc
tggacgaattctgaaacaccttggtcttatttccctaaaatctccatctacctgagagac
gagaactccagcagatcattccgtataactatcctgcctcagctttacattcagcccatg
atgggggctggcctgaattatgaatgttaccggttcggcatctcgccttccaccaacgca
ctggtgattggtgctaccgtcatggagggcttctacgtggtctttgacagagctcagaag
agagtgggcttcgcagccagcccctgtgcagaaatcgcaggtgctccggtgtctgaaatt
tctgggcctttctcaacagaggacatagccagcaactgcgtccctgccctgccgttgaac
gagcctgttttgtggattgtctcctatactctcatgagcgtgtgtggagtcatccttctc
gttttaatcaccctgctgctacttccggtccggtgtaggcatcacccccgagatcccgag
gtggtcaacgatgagtcctcgctcgtacggcatcgctggaaatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (18)   

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