KEGG   Bos indicus (zebu cattle): 109566012
Entry
109566012         CDS       T04792                                 
Symbol
SLC8A1
Name
(RefSeq) sodium/calcium exchanger 1 isoform X1
  KO
K05849  solute carrier family 8 (sodium/calcium exchanger)
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu04020  Calcium signaling pathway
biu04022  cGMP-PKG signaling pathway
biu04260  Cardiac muscle contraction
biu04261  Adrenergic signaling in cardiomyocytes
biu04371  Apelin signaling pathway
biu04740  Olfactory transduction
biu04961  Endocrine and other factor-regulated calcium reabsorption
biu04974  Protein digestion and absorption
biu04978  Mineral absorption
biu05410  Hypertrophic cardiomyopathy
biu05412  Arrhythmogenic right ventricular cardiomyopathy
biu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:biu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    109566012 (SLC8A1)
   04020 Calcium signaling pathway
    109566012 (SLC8A1)
   04022 cGMP-PKG signaling pathway
    109566012 (SLC8A1)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    109566012 (SLC8A1)
   04261 Adrenergic signaling in cardiomyocytes
    109566012 (SLC8A1)
  09154 Digestive system
   04974 Protein digestion and absorption
    109566012 (SLC8A1)
   04978 Mineral absorption
    109566012 (SLC8A1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    109566012 (SLC8A1)
  09157 Sensory system
   04740 Olfactory transduction
    109566012 (SLC8A1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    109566012 (SLC8A1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    109566012 (SLC8A1)
   05414 Dilated cardiomyopathy
    109566012 (SLC8A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:biu02000]
    109566012 (SLC8A1)
   00536 Glycosaminoglycan binding proteins [BR:biu00536]
    109566012 (SLC8A1)
Transporters [BR:biu02000]
 Solute carrier family (SLC)
  SLC8: Na+/Ca2+ exchanger
   109566012 (SLC8A1)
Glycosaminoglycan binding proteins [BR:biu00536]
 Heparan sulfate / Heparin
  Others
   109566012 (SLC8A1)
SSDB
Motif
Pfam: Calx-beta Na_Ca_ex_C Na_Ca_ex DnaG_DnaB_bind
Other DBs
NCBI-GeneID: 109566012
NCBI-ProteinID: XP_019825607
UniProt: A0A6P5CJE3
Position
11:complement(23623781..24071104)
AA seq 934 aa
MLQFSLSPTLSMGFHVIAMVALLFSHVDHISAETEMEGEGNETGECTGSYYCKKGVILPI
WEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETT
KTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIII
ALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFP
ICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVDSF
LDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAF
YRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVAENDPVSKIFFEQGTYQCLENCG
TVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDD
IFEEDENFLVHLSNVKVSLEASEDGILEASHVSTLACLGSPSTATVTIFDDDHAGIFTFE
EPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIV
KIITIRIFDREEYEKECSFSLVLEEPKWIRRGMKGGFTITDEYDDKQPLTSKEEEERRIA
EMGRPILGEHTRLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGED
DDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIG
DLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVF
LGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGG
PRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF
NT seq 2805 nt   +upstreamnt  +downstreamnt
atgctgcagttcagtctgtcacccaccttgtcgatgggatttcacgtgatagccatggtg
gctctcttgttttcccatgtggaccatataagtgctgagacggaaatggaaggagaaggc
aacgagactggcgagtgtactggctcctattactgtaagaagggggtgattttacccatt
tgggagccccaggacccttcctttggagacaaaattgctagagcgactgtgtattttgtg
gccatggtctacatgtttcttggagtctcaatcattgctgaccggttcatgtcctctata
gaagtcatcacgtctcaagagaaagaaatcaccataaagaaacccaatggagagaccacc
aagacaactgtgaggatctggaatgagacagtgtccaacctgaccttgatggccctgggg
tcttcagctccagagattctcctttcagtaatcgaggtgtgtggccataacttcactgca
ggagaccttggtcctagcaccatcgtggggagtgctgcattcaacatgttcatcatcatt
gccctttgtgtgtatgtcgtcccggatggggagacaaggaagatcaagcatctgcgtgtg
ttctttgtgacagcagcatggagcatctttgcctatacctggctttacatcattttgtct
gtcagctcccctggggtcgtggaggtctgggaaggtttgcttactttcttcttcttcccc
atctgcgttgtgtttgcttgggtggcagacaggaggcttctgttttacaagtatgtctac
aagaggtatcgggctggcaagcagaggggaatgattattgaacacgaaggagacaggcca
tcttccaagacagaaattgaaatggatgggaaagtggtcaattcccatgttgacagtttc
ttagatggagccctggttctggaggttgatgagagggaccaagatgatgaagaagccagg
cgagaaatggctaggattctgaaggaactcaagcagaagcatccagagaaggaaatagag
caattaatagaattagccaattaccaagtcttaagtcagcagcaaaaaagtcgagcgttt
taccgtattcaagctacccgcctgatgaccggagcgggcaacattttaaagaggcatgca
gcagaccaagccaggaaagctgtcagcatgcatgaggtcaacacggaagtggctgaaaat
gaccctgtcagtaagatcttctttgaacaagggacatatcagtgtctggagaactgtggc
acagtagccctgaccattatccgcagaggtggtgatttgaccaacactgtgtttgttgac
ttcagaacagaggatggcacagccaatgctggatctgattacgaatttaccgaaggaact
gtggtctttaagcctggtgagacccagaaggaaatcagagttggcatcattgatgatgac
atctttgaggaggatgagaatttccttgtgcatctcagcaacgtcaaagtatctttggaa
gcctcggaagacggcatcctggaagccagtcatgtctctacccttgcttgcctgggatcc
ccctccactgccaccgtgactatttttgatgatgaccatgctggcatctttacttttgag
gaaccggtgactcatgtgagtgagagcattggcatcatggaggtgaaagttctgagaaca
tctggagcacgtggaaatgttatcgttccctataagaccattgaggggaccgccagaggt
ggaggggaggactttgaggacacatgcggagagctcgagttccagaatgatgaaattgtg
aagatcattaccattagaatatttgaccgtgaggaatatgagaaagagtgcagtttctcc
cttgtgcttgaggaaccaaaatggataagaagaggcatgaaaggtggcttcacaataaca
gatgaatatgatgacaagcagccactgaccagcaaagaggaggaagagaggcgcattgcg
gaaatggggcgccccattctgggagagcacaccagactggaggtgatcattgaagaatcc
tacgagttcaagagtaccgtggacaaactgattaagaagacaaacctagccctcgtggtt
gggacgaacagctggagagagcagttcatcgaggcgatcactgtcagtgctggggaagat
gatgatgacgacgaatgtggggaggagaagctgccctcctgttttgactacgtgatgcac
tttctgactgtgttctggaaggtcctcttcgcctttgtccccccgacagagtactggaac
ggctgggcgtgtttcatcgtctccatcctcatgatcggcctactgacagctttcattgga
gacctcgcttcccacttcggctgcaccatcggcctgaaggattccgtgaccgcggtggtg
ttcgttgcgcttggaacctcagtgccagacacatttgcaagcaaagtggccgccacccag
gaccagtatgcggacgcatccataggtaacgtcacaggcagcaacgcggtgaacgtcttc
ctgggcatcggtgtggcctggtccatcgccgccatctaccacgcggccaacggggaacag
ttcaaagtgtcccctggcacgctagctttttctgtcactctcttcaccatttttgctttc
atcaatgtgggggtgctgctgtatcggcggaggccagaaattggaggtgagctgggtggg
ccccggactgccaagctcctcacatcctgcctctttgtgctcctgtggctcttgtacatt
ttcttctcctccctggaggcctactgccacataaaaggcttctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (4)   
   Pfam (4)   
All databases (35)   

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