KEGG T01208: BMQ

Bacillus megaterium QM B1551: BMQ_1293

Entry

BMQ_1293 CDS T01208

Gene name

metH

Definition

methionine synthase, vitamin-B12 dependent (EC:2.1.1.13)

Orthology

K00548

5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]

Organism

bmq Bacillus megaterium QM B1551

Pathway

bmq00270	Cysteine and methionine metabolism
bmq00450	Selenocompound metabolism
bmq00670	One carbon pool by folate
bmq01100	Metabolic pathways
bmq01110	Biosynthesis of secondary metabolites
bmq01230	Biosynthesis of amino acids

Module

bmq_M00017

Methionine biosynthesis, apartate => homoserine => methionine

Class

Metabolism; Amino acid metabolism; Cysteine and methionine metabolism [PATH:bmq00270]
Metabolism; Metabolism of other amino acids; Selenocompound metabolism [PATH:bmq00450]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH:bmq00670]

SSDB

Motif

Pfam:

S-methyl_trans Met_synt_B12 Pterin_bind B12-binding_2 B12-binding CdhD His_biosynth

Other DBs

NCBI-GI:

294498060

NCBI-GeneID:

8985731

UniProt:

D5E063

Position

complement(1275159..1278602)

AA seq 1147 aa
MSSLIEQQLKKRILVIDGAMGTMIQDADLTAEDFGGEEYEGCNEYLTRTAPHVIQRIHEE
YFAAGADIIETNTFGSTSTVLDEYDLGHLAYELNIEAVKLACAARDKYSTPEWPRFVAGA
IGPTTKTLSVTGGITFPELVESYEEQVRGLLDGGVDLLLVETCQDMLNVKAAFLGITAAF
EKLKTEVPIMISGTIEPMGTTLAGQDIESFYLSLEHMKPLSVGLNCATGPEFMTDHIRSL
SDLATSAVSCYPNAGLPDEEGNYHESPELLAQKIKGFADKGWLNFVGGCCGTTPAHIKAL
AEAVKEVAPRSLDRSEHNHAVTGIEPLVYDDSMRPLFVGERTNVIGSRKFKRLIAEGKIE
EASEIARAQVKNGAHVIDICLADPDREEMEDMEEFIQEVVKKVKVPLVIDSTDEKVIEKA
LTYSQGKVIINSINLEDGEERFDAILPLVKKFGAALVVGTIDETGMAVTAERKVEIAKRS
HDLLVEKHGFNPKDIIFDPLVFPVGTGDEQYIGSAEETVKGIKMIKEALPDCLTILGVSN
VSFGLPPVGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASIPEAEIELANALLFNTTDE
TLSTFTDFYRDKKKEAKVEISTLTLEERLAMYIVEGTKEGLLPDLEQALAQYDDPLDIIN
GPLMKGMAEVGRLFNDNQLIVAEVLQSAEVMKASVAFLEPHMEATENDSGKGKVILATVK
GDVHDIGKNLVDIILSNNGFKVIDLGIKVTPQQLIEAVKEEKPDIIGLSGLLVKSAQQMV
LTAQDLTQSSIDVPIMVGGAALSRKFTDFKIAPEYEGAVLYAKDAMDGLALANKLQNKEE
VIQLLADLKTRQEKKVAVRERQPQTAQAATAVLERSAISTDAPVFVPADLKRHVVKHYDL
AQVLPYINWQMLLGHHLGLKGKVNKLLAEKDERAVQLKETVDDLLELALKENLIKPAVIY
QFFPAQADGNDLIIYDPADEKTEIERFTFPRQAKGQFLCLSDFAKPKEKEMDYVCFFSVT
AGTGIRERAAKFKENGEFLKSHVFQALALELAEGLAERVHQQIRDRWGFPDSPDFTMAER
FSAKYQGQRFSFGYPACPDLEDQAKLFKLLKPEDIGIQLTDGFMMEPEASVTALVFAHPE
AKYFNVL

NT seq 3444 nt +upstreamnt +downstreamnt
atgagctcacttatcgaacaacaactaaagaagcgaatactcgtcatcgatggagcaatg
ggaacgatgattcaagatgctgatttaaccgctgaagattttggcggcgaagaatatgaa
ggctgtaacgaatatttgactcgaacagcgcctcatgtgattcagcgcattcatgaagag
tactttgcagcaggtgccgacatcattgaaaccaatacgtttggctcaacatctaccgta
cttgatgaatacgatttaggtcacttggcttatgaattgaatatcgaagctgtgaagctt
gcttgtgcagcccgcgataaatattcaactcccgaatggcctaggttcgtagctggagct
atcggtcctaccactaaaactctctctgttaccggaggcattacattccctgagttagta
gaatcgtacgaagagcaagttcggggtttgttagacggcggcgttgacttacttttagtc
gaaacctgtcaagacatgctgaacgtaaaagccgcgtttctagggattacagcggcgttt
gaaaaactaaaaaccgaagttcctattatgatttcaggaacaattgagcctatgggaaca
actctcgctggtcaagatatcgaatctttttacttatcactggaacacatgaagcctctt
tcagtcggacttaactgcgcgacaggccctgaatttatgacggatcatattcgctctctt
tcagacctagccacttcagcagttagctgttatccaaacgctggacttccggatgaagaa
ggcaattatcatgaatcccctgagctgcttgctcaaaaaattaaagggtttgctgataaa
ggctggctgaactttgtaggcggatgctgtggtacaacgcctgctcatattaaagcactg
gctgaagcggtaaaagaggttgcgcctcgttcgctcgatcgctccgagcataaccatgct
gtaaccggtattgaaccacttgtatatgacgattctatgcgccctctttttgtgggagaa
cgtacgaatgtaatcggttctcgcaagttcaagcgtctgattgcagaaggaaaaattgaa
gaagcatctgaaattgcgcgtgctcaagttaaaaatggtgctcacgttattgatatttgc
ttagcagatccagaccgtgaagaaatggaagacatggaggaatttattcaagaagttgta
aaaaaagtgaaggttcctcttgtaatcgattcaacggacgagaaagttattgaaaaagct
ttaacgtactcacaaggtaaggtcattattaactccattaacttagaagatggtgaagag
cgttttgatgcaatcttaccgctagtaaaaaaattcggtgcagctctggttgtcggtaca
atcgatgaaacaggcatggccgttactgcagaacgaaaagtagagattgctaaacgctca
catgatttgcttgttgaaaaacatggctttaatccaaaagatattatttttgaccctctt
gtgtttcctgtagggactggtgatgaacaatatattggttctgctgaagaaacagttaag
ggaattaaaatgattaaagaagccctgcctgattgcctgaccattcttggcgtaagtaac
gtgtcattcggtcttcctccagtcggacgtgaagtactaaatgccgtttacctttatcac
tgtacgcaggctggactcgattatgccattgtcaataccgaaaagttagagcgctatgct
tctattccagaagctgaaattgagcttgctaatgcgttattatttaacacaactgatgaa
acgttaagcacgtttaccgacttttatcgtgataaaaagaaagaagcaaaagtagaaatt
tctacgttaacactcgaagaacgattggcaatgtatattgtcgaaggtacaaaagaagga
ttgcttcctgatttagaacaggctttagctcaatatgatgatccgttagatattattaac
ggaccgcttatgaagggcatggcggaagttggacgtttgtttaatgacaaccagctgatt
gtagcagaagtgcttcaaagtgcggaagtgatgaaagcatccgttgcctttttagaacct
catatggaagcaactgaaaatgattctggaaaaggcaaagttattcttgcaacggttaaa
ggcgacgtgcatgatatcggtaaaaacttagtagacatcattttaagcaacaatggtttt
aaagtaattgatttagggattaaagtaacgccgcagcagctgattgaagcagtaaaagaa
gaaaagccagacatcattggcctgtcaggtcttctagtaaagtcagctcagcaaatggtt
ttgactgcccaagatttaacacaatcaagcattgatgttccaattatggtaggaggcgct
gccctttcccgtaaatttactgactttaaaattgccccggaatatgaaggtgcggtcctc
tacgccaaagatgcgatggacggattagcgttagcaaataagctgcagaacaaagaagaa
gttattcagcttttagcagatttaaaaacgcggcaagaaaagaaagtagcggttcgagaa
cgccagcctcaaaccgctcaagcagctacggctgttttagaaagatccgccatttcaacg
gacgctcctgtttttgtaccggctgatttaaagcggcacgttgtcaaacactacgatttg
gcacaggttcttccgtatattaactggcagatgcttttaggccatcacttaggactaaaa
ggaaaagtgaataagctgcttgctgaaaaagacgagcgtgctgttcaattaaaagaaacc
gttgatgacctgctcgaactggcactaaaagaaaacttaattaagccagcggttatttat
cagttcttccctgctcaagcagacggaaatgatttaattatttatgatcctgctgatgaa
aaaacagaaattgaacgctttaccttccctcgacaagcaaaaggacagttcctgtgctta
tctgattttgcaaagcctaaagaaaaagagatggactatgtatgtttcttctctgtaaca
gcaggaacaggcattcgcgaacgcgccgcgaaattcaaagaaaacggcgagtttttaaag
agtcacgtgttccaagctcttgcgcttgaactagctgaaggattagcagaacgtgttcat
cagcaaattcgtgaccgctggggattccccgattcgcctgactttacaatggcggagcgt
ttttcagccaaataccaaggtcagcgtttttcattcggatatcctgcatgtccagacctt
gaggaccaagcaaaactgtttaaattacttaaacctgaagacatcggcattcagttaaca
gacggtttcatgatggaaccagaagcttctgttacagcccttgtttttgcacatcctgaa
gcgaaatattttaacgtgttataa

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (32)   

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