KEGG   Bos mutus (wild yak): 102274461Help
Entry
102274461         CDS       T02919                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
bom  Bos mutus (wild yak)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:bom00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102274461 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102274461 (PIK3CD)
   04015 Rap1 signaling pathway
    102274461 (PIK3CD)
   04012 ErbB signaling pathway
    102274461 (PIK3CD)
   04370 VEGF signaling pathway
    102274461 (PIK3CD)
   04630 Jak-STAT signaling pathway
    102274461 (PIK3CD)
   04668 TNF signaling pathway
    102274461 (PIK3CD)
   04066 HIF-1 signaling pathway
    102274461 (PIK3CD)
   04068 FoxO signaling pathway
    102274461 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    102274461 (PIK3CD)
   04024 cAMP signaling pathway
    102274461 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    102274461 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    102274461 (PIK3CD)
   04152 AMPK signaling pathway
    102274461 (PIK3CD)
   04150 mTOR signaling pathway
    102274461 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102274461 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    102274461 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    102274461 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    102274461 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102274461 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    102274461 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    102274461 (PIK3CD)
   04660 T cell receptor signaling pathway
    102274461 (PIK3CD)
   04662 B cell receptor signaling pathway
    102274461 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    102274461 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    102274461 (PIK3CD)
   04670 Leukocyte transendothelial migration
    102274461 (PIK3CD)
   04062 Chemokine signaling pathway
    102274461 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    102274461 (PIK3CD)
   04915 Estrogen signaling pathway
    102274461 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    102274461 (PIK3CD)
   04917 Prolactin signaling pathway
    102274461 (PIK3CD)
   04921 Oxytocin signaling pathway
    102274461 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    102274461 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102274461 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102274461 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102274461 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    102274461 (PIK3CD)
   04722 Neurotrophin signaling pathway
    102274461 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102274461 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    102274461 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102274461 (PIK3CD)
   05230 Central carbon metabolism in cancer
    102274461 (PIK3CD)
   05231 Choline metabolism in cancer
    102274461 (PIK3CD)
   05205 Proteoglycans in cancer
    102274461 (PIK3CD)
   05203 Viral carcinogenesis
    102274461 (PIK3CD)
   05210 Colorectal cancer
    102274461 (PIK3CD)
   05212 Pancreatic cancer
    102274461 (PIK3CD)
   05214 Glioma
    102274461 (PIK3CD)
   05221 Acute myeloid leukemia
    102274461 (PIK3CD)
   05220 Chronic myeloid leukemia
    102274461 (PIK3CD)
   05218 Melanoma
    102274461 (PIK3CD)
   05211 Renal cell carcinoma
    102274461 (PIK3CD)
   05215 Prostate cancer
    102274461 (PIK3CD)
   05213 Endometrial cancer
    102274461 (PIK3CD)
   05222 Small cell lung cancer
    102274461 (PIK3CD)
   05223 Non-small cell lung cancer
    102274461 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102274461 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102274461 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102274461 (PIK3CD)
   05166 HTLV-I infection
    102274461 (PIK3CD)
   05162 Measles
    102274461 (PIK3CD)
   05164 Influenza A
    102274461 (PIK3CD)
   05161 Hepatitis B
    102274461 (PIK3CD)
   05160 Hepatitis C
    102274461 (PIK3CD)
   05169 Epstein-Barr virus infection
    102274461 (PIK3CD)
   05146 Amoebiasis
    102274461 (PIK3CD)
   05145 Toxoplasmosis
    102274461 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    102274461 (PIK3CD)
Enzymes [BR:bom01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102274461 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1013 aa AA seqDB search
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKFHMLSDPEAYVFT
CVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSL
QDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRVLL
VNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLY
GSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKP
SSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVW
KQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQ
LKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKI
LELGRLGEHGRFTEEEQLQLRESLERRGXGRSLEPDAARTPALTARILLQMLYLLCSWPE
LPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFK
NLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSK
LKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTF
MDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMT
PYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRA
IEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVP
FILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSC
SKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
NT seq 3042 nt NT seq  +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagaacgtg
gcagttgatttcttgctccccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcactatcaagaagttccacatgctcagtgaccctgaggcctacgtgttcacc
tgcgtcaaccagacggcggagcagcaggagctggaggacgagcagcggcggctctgcgac
atccagcccttcctgcccgtcctgcggctggtggcccgcgagggtgaccgcgtgaagaag
ctcatcaactcgcagatcagcctgctcatcggcaaaggcctccacgagtttgactccttg
caagacccggaggtgaatgacttccgaggcaagatgcgccagttctgcgaggaggcggct
gcccgcaggcagcagctgggctgggaggcctggctgcagtacagcttccctctgcagttg
gagccctcggcgcggagctgggggccaggcaccctgcgcgtccccaatcgggtcctcctg
gtcaatgtcaagtttgagggcagcgaggagagcttcaccttccaggtatccaccaaggat
gtgcccctggcactgatggcctgtgccctccgaaagaaggccacggtgttccggcagccg
ctggtggagcagcctgaggactacacgctgcaggtgaacggcaagcacgagtacctgtac
ggcagctaccccctctgccagttccagtacatctgcagctgcctgcacagtgggctgacc
ccgcacctgaccatggtgcactcctcctccatcctcgccatgcgggacgagcagagcaac
cccgccccccaagtccagaagccacgcaccaaaccaccccccatccccatgaagaagccc
tcctctgtgtccctctggtccctggagcagcctttctacatcgagctgatccagggcagc
aaagtgaatgccgacgagcggatgaagctggtggtgcaggccgggctcttccatggcaat
gagacgctatgcaagacggtgtccagctcggaggtgagcgtgtgctcggagcccgtgtgg
aagcagcggctggagtttgacatcaacatctgtgacctgccccgcatggcccggctctgc
ttcgcgctttacgctgtgatcgagaaggccaagaaggcccgctccaccaagaagaagtcc
aagaaggcggactgccccattgcctgggccaacctcatgctgtttgactacaaggaccag
ctcaagacgggcgagcactgtctctatatgtggccctctgtcccagacgagaaaggggaa
ctactgaacccctgtgggaccgtgcggagtaaccccaacactgagagtgcagccgccctg
gtcatctttctccctgaggtggcccctcaccctgtatactacccttccctggacaagatc
ctggagctggggcggcttggagagcatggacgcttcacggaggaggagcagctgcagctg
cgggagagcctggagcggcggggnnaggggcggagcctggagccagacgcagcccgcacc
cccgccctgaccgctcgcatcctcctccagatgctctacctgctctgctcctggcctgaa
ctgcccgttctgagcgccctggagttgctagacttcagcttccccgaccgccacgtggga
tccttcgccatcaagtccctgcggaaactaacggacgacgagcttttccagtacctgctg
cagctggtgcaggtgctcaagtacgagtcctacctcgactgcgagctgaccaaattcaaa
aacctgctggaccgggccctggccaatcgcaggatcggccacttcctcttctggcacctc
cgctccgagatgcacgtgccgtcggtggccctgcgcttcggccttatcatggaagcctat
tgccggggcagcactcaccacatgaaagtgctgatgaagcagggggaagcactgagcaaa
ctgaaggccctgaacgacgtcgtcaaagtgagctcccagaagaccaccaagccccagacc
aaggagctgatgcacctgtgcatgcgccaggagacctacctggaggccctctcccacttg
cagtccccactcgaccccagcaccctgctggctgaagtctgcgtggagcagtgcaccttc
atggactccaagatgaaacccctgtgggtcatgtacagcaacgaggaggcaggcagcgac
ggcaccgtgggcatcatctttaagaatggggacgacctccgccaggacatgctgaccctg
cagatgatccagctcatggacattctgtggaagcaggagggcttggacctgaggatgacc
ccctacggctgcctctccactggggaccgcacaggccttatcgaggtggtgcttcactcg
gacaccattgccaacatccagctgaacaagagcaacatggcggccacggctgccttcaat
aaggatgctctgctcaactggctcaagtccaagaaccctggggaggccctggatcgagcc
attgaggagttcaccctctcctgtgctggctactgtgtggctacctatgtgctgggcatt
ggcgatcgtcacagcgacaacatcatgatccgagagaacgggcagctgttccacattgat
ttcggccactttctggggaatttcaagaccaagtttggaatcaaccgtgagcgggtcccg
ttcatcctcacctatgactttgtccacgtgatccagcaagggaagacgaataatagtgag
aagtttgaaaggttccggggctactgtgagagggcctacaccatcctgcggcgccatggg
ctccttttcctccacctctttgccctgatgcgggcggcaggcctgcctgagctcagctgc
tccaaagacatccagtatctcaaggattctctggcattggggaaaacggaggaggaggct
ctgaagcacttccgagtgaagtttaatgaagccctccgggaaagctggaaaaccaaagtg
aattggctggcccacaacgtgtccaaagataacaggcaataa

DBGET integrated database retrieval system