KEGG   Bos mutus (wild yak): 102285317Help
Entry
102285317         CDS       T02919                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
bom  Bos mutus (wild yak)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:bom00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102285317 (INSR)
   04015 Rap1 signaling pathway
    102285317 (INSR)
   04010 MAPK signaling pathway
    102285317 (INSR)
   04066 HIF-1 signaling pathway
    102285317 (INSR)
   04068 FoxO signaling pathway
    102285317 (INSR)
   04072 Phospholipase D signaling pathway
    102285317 (INSR)
   04022 cGMP - PKG signaling pathway
    102285317 (INSR)
   04151 PI3K-Akt signaling pathway
    102285317 (INSR)
   04152 AMPK signaling pathway
    102285317 (INSR)
   04150 mTOR signaling pathway
    102285317 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    102285317 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    102285317 (INSR)
   04923 Regulation of lipolysis in adipocyte
    102285317 (INSR)
   04913 Ovarian Steroidogenesis
    102285317 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102285317 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    102285317 (INSR)
   04213 Longevity regulating pathway - multiple species
    102285317 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102285317 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102285317 (INSR)
   04931 Insulin resistance
    102285317 (INSR)
Enzymes [BR:bom01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102285317 (INSR)
Protein kinases [BR:bom01001]
 Tyrosine protein kinases
  InsR family [OT]
   102285317 (INSR)
Enzyme-linked receptors [BR:bom01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   102285317 (INSR)
Cytokine receptors [BR:bom04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   102285317 (INSR)
CD molecules [BR:bom04090]
 Proteins
  102285317 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 1382 aa AA seqDB search
MGAGGGRGAAAVLLMVVVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDARPSRKRRALGDVGNVTAAVPTALGL
PNTSSTSTPMSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV
SRRHYALERGCRLRGLLPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSICLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN
CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME
FEDMESVPLDRASHAQREEAGGRDGGSALGLKRNYDEHIPYTHMNGGKKNGRILTLPRSN
PS
NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt
atgggcgccgggggcgggaggggggcggcagccgtgctgctgatggtggtcgtcgccgcg
ctgctggtgggcgccgcgggccacctgtaccctggagaagtgtgccccggtatggatatc
cggaataatctcacccggctgcatgagctggccaactgctcagtcatcgaaggacatttg
cagattctgttgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag
gacttgttccccaacctcacggttatccgaggctcacgcctcttctttaattatgcgctg
gtcatctttgagatggttcacctgaaggagcttggcctctacaacctgatgaacatcacc
cgggggtctgtccgcattgagaagaacaatgaactctgctacctggccaccatcgactgg
tctcgcatcctggattccgtggaggataattatatcgtgctgaacaaagacgacaatgag
gagtgtggggacatttgtccaggcaccgccaagggcaagaccaactgccctgccactgtc
atcaacgggcaatttgtggagcggtgctggacacacagccactgccagaaagtgtgtccg
accatctgcaagtcacatggctgcacctctgagggtctctgctgccacagcgagtgcttg
ggcaactgctcagagcccgacgaccccaccaagtgtgtggcctgtcgcaacttctacctg
gacggcaggtgtgtggagacctgcccgcccccttactaccacttccaagactggcgctgc
gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcaaggc
tgccaccagtatgtcattcacaataacaagtgcatccccgagtgcccctctggctacacg
atgaattccagcaacttgatgtgtaccccttgcctgggcccctgtcccaaggtatgccac
ctcctggaaggcgagaagaccatcgattcggtgacatctgcccaggagctccgaggctgc
accatcatcaacggaagcttaatcatcaacattcgagggggcaacaacctggcagctgag
ctagaggccaaccttggactcattgaagaaatttcaggatatctgaaaatccgccggtcc
tatgccctggtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg
gaaattgggaactactctttctacgccttggacaaccagaacctaaggcagctgtgggac
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa
ctctgcctgtcggaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag
agaaatgacattgctctaaagaccaatggggaccaggcatcctgtgaaaatgaattactt
aaattttcttacattcggacatcttacgacaagatcttgctgaaatgggagccgtattgg
cctcctgacttccgagacctcctggggttcatgttgttctacaaagaggccccttaccag
aacgtgacagaattcgatgggcaggatgcgtgcggctccaacagctggacagtggtggat
attgacccgcctacgaggtccaacgaccccaagtcacagaaccaccctgggtggctgatg
cgtggtctcaagccctggacccagtatgccatctttgtcaagaccctggtcaccttttct
gatgaacgccgtacatacggggccaagagtgacatcatctatgtccagacagacgccact
aatccttccgtgcccctggatcccatctcagtttctaattcctcgtcccagattattctg
aaatggaagcctccctccgaccccaatggcaatatcacacactacttggtgttctgggag
agacaggcggaagacagtgagctgtatgaactggattattgcctcaaagggttgaagctg
ccctcccggacctggtctccaccattcgagtcggagggctcccagaagcacaatcagagt
gagtatgaggagtctgctggtgaatgctgctcctgcccaaagaccgactcgcagatcctc
aaggagctggaggagtcctcgttcaggaaaacgtttgaagattacctgcacaacgtggtt
tttatccccagaaaatcatcttcaggccctgttgccgaggacgctaggccttcgaggaaa
cgcagagcccttggtgacgtggggaatgtgacagcagccgtgcccaccgctctggggctc
cccaatacctcctccaccagcacgcccatgagctcggaggagcacagacccttcgagaaa
gtggtgaacaaggagtcgctggtcatctccggcctgcgtcactttactggctatcgaatc
gagcttcaggcttgcaaccaagattcccccgaggagaggtgtagcgtggctgcctatgtc
agcgccaggaccatgcctgaagccaaggcagatgatattgttggccccgtgacccatgaa
atcttcgagaacaacgttgttcacttgatgtggcaggagcccaaggaacccaacggtctg
attgtgctgtatgaagtgagttaccgacgatacggcgaggaggagctgcacctctgcgtc
tcccgccgacattatgctctggagcgtggctgccggctgcgtgggctgctgcctgggaat
tacagtgtgcgagttcgggccacctccctggcaggcaatgggtcttggacggaagccacc
tatttctacgtgacagactatttagacgtgccatcaaatattgcaaaaatcatcatcggt
cccctcatctttgtctttctcttcagtgttgtgattggaagtatttgtctattcctgaga
aagaggcagccagatgggccattgggaccactgtatgcttcttcaaacccagagtacctc
agtgccagcgatgtgtttccatgctctgtgtatgtgccggacgagtgggaggtgcctcga
gagaagatcacactcctgcgagaattggggcaaggctcctttggcatggtgtacgagggc
aacgccagggacattgtcaagggtgaggcggagacgcgcgtggcagtgaagacggtcaac
gagtcagccagcctgcgagagcggatcgagtttctcaacgaggcttcggtcatgaagggc
ttcacctgccaccatgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctg
gtggtgatggagttgatggctcacggagacctgaagagttacctccgttccctgcggcct
gaggctgagaataaccccggccgccctccgcctaccctgcaagaaatgattcagatggcg
gcagagatcgccgatgggatggcatacctgaacgctaagaagttcgtgcaccgggatctt
gcagcccggaactgcatggttgcccacgactttacagtcaaaattggagactttggaatg
acaagagacatctatgaaacggattactaccggaaagggggcaaaggtctgctccccgtg
cggtggatggcacctgaatccctgaaggacggagtcttcaccacctcttcagacatgtgg
tcttttggtgtggtcctttgggaaattaccagcttggcagaacagccttaccaaggtcta
tcaaatgagcaggtgctgaaatttgtcatggatggagggtacctggatcaacctgacaat
tgtccagagagagtcaccgacctgatgcggatgtgctggcagttcaaccccaagatgcgt
ccaaccttcctggagatcgtggacctgctcaaggacgacctgcaccccagctttcccgaa
gtgtccttcttccacagcgaggagaacaaggcgcccgagagcgaggagctggagatggag
tttgaggacatggagagcgtgcccctggaccgggcctcgcacgcgcagagagaggaggcc
gggggccgggatggagggtcggcgctggggctaaagcgaaactatgacgagcacatcccc
tacacccacatgaacgggggcaagaaaaacggacggattctgactttgccccggtcaaat
ccttcctaa

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