KEGG   Bacillus subtilis subsp. subtilis 168: BSU04570
Entry
BSU04570          CDS       T00010                                 
Symbol
murF
Name
(RefSeq) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
bsu  Bacillus subtilis subsp. subtilis 168
Pathway
bsu00300  Lysine biosynthesis
bsu00550  Peptidoglycan biosynthesis
bsu01100  Metabolic pathways
bsu01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:bsu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    BSU04570 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    BSU04570 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    BSU04570 (murF)
Enzymes [BR:bsu01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     BSU04570 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase Glyco_hydro_30 VMAP-C
Other DBs
NCBI-GeneID: 939947
NCBI-ProteinID: NP_388338
Pasteur: BG12084
UniProt: P96613 A0A6M4JIN4
Position
509384..510757
AA seq 457 aa
MIKRTVKNIAEMVKGTLANPQYEQTVIHGVATDTRKLEQHQLFIPLKGERFDGHSFVEQA
FEAGVAAVLWDRSVPNPPENHAVILVDDTLTALQQLAKAYLQELGTRVIGVTGSNGKTTT
KDMIHAVLGTQYRVHKTGGNFNNHIGLPLTVLAMPENTEIAVLEMGMSAKGEIDLLSRLA
NPDAAVITNIGESHMQDLGSREGIAEAKLEIINGLKEDGVLIYIGDEPLLQNAYSCQTKT
YGTGTHNDYQLQDVSQSEEGTHFTIKGIENTFFIPILGKHNVMNAMAAIAAGAYFGIAPE
DAAKGLSGLKVTGMRLELIKTDSGLSIINDAYNASPTSMKAAIQLTESLEGYGKKMLVLG
DMLELGDLEETFHKECGAVISPDKIDRVFTYGKLGAFIAEGALKHFEKDRVSHYTEKKDL
LQAVKENASKGDLILFKASRGMKLEEIVKDLIESPLS
NT seq 1374 nt   +upstreamnt  +downstreamnt
ttgattaagcgaacagtaaaaaacattgccgaaatggttaaaggcacactagcaaatccg
caatatgaacaaacagtcattcatggagtggcaaccgatacaagaaaactggaacaacat
cagctctttattccgctgaaaggggaacgttttgacggccactcttttgtggagcaggcc
tttgaagctggtgtagcggctgttctttgggatcggtcagtaccaaatccgcccgagaat
cacgccgtcattttagtggacgatacccttactgcacttcagcagcttgcaaaagcttat
ttgcaggagcttggcacgcgtgtcatcggagtaaccggaagcaatggcaaaacgacaaca
aaagatatgattcacgccgtattggggacccagtaccgtgtccacaaaactggaggaaac
ttcaataatcatatcggtttgccgctgacggttttagcgatgcctgaaaatacggagatc
gccgtattggagatgggaatgagcgccaaaggagaaattgacctcttgagccgactggca
aacccggatgcggcagtgattacgaatatcggcgaatcgcatatgcaagacctcggctct
agagagggcatcgcggaggcgaagcttgaaatcataaacgggcttaaagaagacggagtg
ctgatttatatcggggacgaaccgcttcttcaaaatgcatacagctgccagacgaaaacg
tacggtacgggaacgcataatgattatcagcttcaggatgtcagccagagtgaggaagga
acccattttacaatcaaagggatagaaaacacgttttttattccaatactcggcaagcac
aatgtgatgaacgccatggctgcaattgctgcaggggcttattttggcatcgcgcctgag
gatgcggcaaaaggactgagcggcctaaaggtaaccgggatgaggcttgaactcatcaaa
acagacagcggcctttcgataatcaatgacgcttataatgcgagcccgacttccatgaaa
gctgcaattcaattgacagaaagccttgaaggctacggcaaaaaaatgctcgtgctcggt
gatatgcttgaactcggcgatcttgaagaaacgttccataaagagtgcggcgctgtgatc
agccctgataaaattgaccgcgtctttacgtacggaaaactgggagcttttatcgcggaa
ggcgccctgaaacactttgagaaagaccgcgtcagccattacactgagaaaaaagatctc
cttcaagctgtgaaggaaaacgcatcaaaaggcgatttgattttattcaaagcgtccaga
ggtatgaagcttgaagaaatcgttaaagatttaatagagagcccgctttcataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   PASTEUR (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (41)   

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