KEGG   Bacillus subtilis BEST7613: BEST7613_5664Help
Entry
BEST7613_5664     CDS       T02410                                 

Gene name
hemD
Definition
uroporphyrin-III synthase
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
bsub  Bacillus subtilis BEST7613
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
Heme biosynthesis, glutamate => protoheme/siroheme
Brite
KEGG Orthology (KO) [BR:bsub00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    BEST7613_5664 (hemD)
Enzymes [BR:bsub01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     BEST7613_5664 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     BEST7613_5664 (hemD)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
5929055..5930542
Genome map
AA seq 495 aa AA seqDB search
MGPVAYLTQRAIAVLGRANVVIYDALVSQELFDLLPPDCERIFVGKRGGQPSTPQAKINQ
LLVDHYRRGKQVVRLKSGDPWIFGRIMPELATLVTHHCAYEVVPGISSAIAGAGLASIPL
TAKDSGAGFFVMDGHDPHRWPWPALAQLPTLVILMGTKNLSLLVNELVRAGKSPHTPMAV
IKNAGRPEQQTWEGTLADMVEKTQGQSLAPAVIVIGDVVSQRIIPALPPLPLTEKTILVT
RAADQASQFTELLHQQGATVLAMAALEIVPPKDWQPLDQAIAKLGDFDWLILTSANGVEF
FFQRLQHHGLDSRALAGLKLAVVGKKTAQSLEKFGLKPDFIPPDFIADALVEHFPHSPAG
LKILFPRVESGGRAQLVQELSQKQALVTEVPSYQSACPGHMPEEVWQSIVNQTVDVITFA
SSKTVSHFRQLLAQTSQANGYQDWRSLINHCQIASIGPQTSERCLRELGRVDIEATEYTL
EGLTGAITNYVYQNP
NT seq 1488 nt NT seq  +upstreamnt  +downstreamnt
ttggggcccgtggcctacctgactcaaagggcgatcgccgtgttgggtagggcaaatgtg
gtaatttatgacgccttggtgtcccaggagctttttgatctcctgccgccagattgtgag
cgaattttcgtcggcaaacgggggggacaacccagcactccccaggccaaaattaatcag
ttattggtggaccattaccgacggggcaaacaggtagtacggctgaaaagcggtgatccc
tggatttttggccgcattatgccggaattggcaaccctagtgacccaccattgtgcctat
gaagtagtaccaggaatttcctcggcgatcgccggggcaggactagcaagcattcccctc
acagccaaagatagcggggcgggtttttttgtcatggacggccatgatccccaccgttgg
ccttggcctgccctggcccaattgcccactttggtaattctcatggggaccaaaaatttg
tcgttgttggtcaatgagttagtccgagcaggtaaatctccccacacccccatggcagtg
attaaaaatgccggcagaccggaacagcaaacctgggaaggaaccctagctgatatggtg
gaaaaaacccaaggacagtccctcgccccagcggtaattgtcattggagatgttgttagt
caaaggattattcccgccttgcctcccctgcccctgaccgaaaaaactattctggttacc
agggccgccgaccaagcgagccagtttaccgagcttttgcaccagcaaggggccaccgtc
ttagccatggctgccctggaaattgtgccccccaaggactggcaacccctcgaccaggcg
atcgccaagttgggggattttgactggctaattctgacttccgccaatggggtggagttc
ttttttcaaagattgcaacaccacggtttggacagtagggccctggcgggattaaagttg
gcggtagtgggcaaaaagaccgcccaaagcctagaaaaatttggtctcaagccagatttc
attcccccggatttcattgccgatgccctggtggaacattttccccactccccagcagga
ctaaaaatactttttccccgggtggaaagtggtggccgggcccaattagtccaagaattg
agccaaaaacaagccttggttacggaagtcccctcctatcaatccgcctgccctggccat
atgcccgaagaagtgtggcaaagtatcgttaatcaaacggtggatgtgatcacctttgcc
agttccaaaaccgtcagccattttcggcaactgttggcccagactagccaagctaacggt
taccaagattggcgttccctaattaaccattgccaaatcgcttccattggcccccaaact
tccgaacgctgtttacgggaattgggtcgggtggacattgaagcaacggagtacacccta
gaaggcctaaccggggccattactaattatgtttaccaaaatccgtga

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