KEGG   Bos taurus (cow): 107131843
Entry
107131843         CDS       T01008                                 
Symbol
IRS3
Name
(RefSeq) insulin receptor substrate 1 isoform X1
  KO
K17445  insulin receptor substrate 3
Organism
bta  Bos taurus (cow)
Pathway
bta04022  cGMP-PKG signaling pathway
bta04068  FoxO signaling pathway
bta04140  Autophagy - animal
bta04152  AMPK signaling pathway
bta04211  Longevity regulating pathway
bta04213  Longevity regulating pathway - multiple species
bta04910  Insulin signaling pathway
bta04920  Adipocytokine signaling pathway
bta04923  Regulation of lipolysis in adipocytes
bta04930  Type II diabetes mellitus
bta04935  Growth hormone synthesis, secretion and action
bta05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    107131843 (IRS3)
   04022 cGMP-PKG signaling pathway
    107131843 (IRS3)
   04152 AMPK signaling pathway
    107131843 (IRS3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    107131843 (IRS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    107131843 (IRS3)
   04923 Regulation of lipolysis in adipocytes
    107131843 (IRS3)
   04920 Adipocytokine signaling pathway
    107131843 (IRS3)
   04935 Growth hormone synthesis, secretion and action
    107131843 (IRS3)
  09149 Aging
   04211 Longevity regulating pathway
    107131843 (IRS3)
   04213 Longevity regulating pathway - multiple species
    107131843 (IRS3)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107131843 (IRS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    107131843 (IRS3)
SSDB
Motif
Pfam: IRS PH
Other DBs
NCBI-GeneID: 107131843
NCBI-ProteinID: XP_015315996
Ensembl: ENSBTAG00000046753
VGNC: 108936
UniProt: G3N0N9
Position
25:complement(35984372..35991310)
AA seq 591 aa
MLRAARGQTKSGAGERRGVSRPVRTPPPSPGTALSTPPLPVPSQPSQPLASATWLLWARM
KPGDPTTTPEAQSAAVALGPPRPWVCPADVRLCGHLRKQKSQRRRFFVLRADPPRLECYE
SEKKFRAGRTPPKFSVSLGGACTISKRMDARQRHLIVLYTRDRSLGVAAASEAEQQAWYS
ALLEARATAGPSSHEDPGAWILAPFQDVWPVTLRPKGLGRARGLGSGGYCLCLGSGVLSL
LRKPGGRGSGATGASPPPALRLSLLSVRRCGHADSFFFLELGRSAPTGPGELWLQAPDAV
VAQSIHETVLAAMKRIGDSGAVGRAEPLPRKPPTGAFRPSVPQSYETPDSAAQTSELYRR
NGPSETSEQATLKTLARLGEAVSNPARLEQGGGYITMGAGSDYEPMKGGQAGGYVVMEPP
GLPASTKAASRQPLQDGGVTEYVTMSCCAPRSFSSSFLPLSSGAGEPGPGLQGVHLGIRD
GWGRAGAQPCLQPPSELAGEYVCIEYAAADYIGMGTANPEPPDQGLNYVDLDLVPPLEVR
GHAPGARSRPHSYARLEFQNLAEAGVRRHPTPISLPTPTPASPRQDTTQYS
NT seq 1776 nt   +upstreamnt  +downstreamnt
atgctgcgcgcagcgaggggccaaacgaagtcgggagcaggagagagacgcggagtatcc
agaccggtcaggacgccgcccccgtccccggggaccgctctttctaccccgcctctgcca
gtcccttcccagccgtcccagccccttgcttcggccacctggttgctttgggcaagaatg
aagcccggagaccccacgacgaccccagaggcccagtcggccgccgtggctctgggtccg
ccgcggccctgggtctgcccggctgacgtgcggctctgcggccacctgcggaagcagaag
tcccaacgccgccgcttttttgtgctccgcgccgacccgccgcgccttgagtgttacgaa
agcgagaagaagttccgtgccggccgaacgccgcccaagttcagcgtgagcctggggggc
gcctgcaccatcagcaagcgcatggacgcgcgccagcgccacctgatcgtcctgtacacg
cgcgaccgcagcctgggcgtggcggcggccagcgaggcggagcagcaggcgtggtacagc
gccctgctcgaggcgcgcgccaccgccggtcccagttcccacgaggaccccggggcctgg
atcctcgctccatttcaggacgtctggcctgtgacgctgcgacccaaggggctggggcgg
gcacgaggcctgggcagcggcggctactgcctgtgcctgggttccggggtactgagtctg
ctgcggaagccagggggcagaggctccggggccaccggggcatctccgccgccggccctg
cgcctgtccctgctcagcgtgcgccggtgcggccacgcagactctttcttcttcctggag
ctcggccgctcggcacccacgggtcccggggagctgtggctacaggcccccgacgccgtg
gtggcccaaagcattcacgagaccgtcctggccgccatgaagcgaatcggggacagtggt
gctgttggcagggctgagccactgccaagaaagcccccaacgggagctttcagaccctct
gtcccccaatcttatgagaccccagactccgcggcccaaacaagcgagctgtaccgtcgg
aatggcccgagtgagaccagcgagcaagcaaccctcaagaccctggcgaggcttggggag
gcagtctccaaccctgcgaggttggagcagggcgggggctacataacaatgggagccggg
agtgactacgagcccatgaagggcggccaagccggcggctacgttgtgatggagcccccg
ggccttcccgcttccaccaaagcagcttcccgccagccgctccaggatggaggggtcact
gaatacgtgaccatgagctgttgtgcaccacggtccttttcctcaagtttcttgcctctt
tcctccggggccggggagcctggacccgggctccaaggcgttcatctcggcatccgagac
ggctggggacgggctggggctcagccctgcttgcagccgccatcagagttagccggggag
tacgtatgcattgagtatgcggctgcggactacataggaatgggcactgccaaccccgag
cccccggaccaaggcctcaactacgtggacctggatctggtccctcccctggaggtgcga
ggccacgcccctggggccaggtcccgcccacatagctacgctcggctggagttccagaac
ctcgcggaggccggggtgagaagacatcccacccccatctccctgccaactcccaccccc
gcctcccctcgacaggacaccactcagtatagctga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (2)   
   Pfam (2)   
All databases (46)   

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